Clindamycin sugar-free granules for dogs and cats and preparation method thereof

Abstract

The invention relates to clindamycin sugar-free granules for dogs and cats and a preparation method of the clindamycin sugar-free granules, and the sugar-free granules take clindamycin phosphate as amain drug and further comprise fructo-oligosaccharide, a diluent, an adhesive, a flavoring agent and other pharmaceutic adjuvants. The clindamycin oral drops overcome the defect that existing clindamycin oral drops on the market are poor in palatability, and meanwhile the clindamycin oral drops can be used for dogs and cats suffering from diabetes and obesity. The clindamycin sugar-free granules prepared by the method disclosed by the invention are good in taste, good in solubility, more convenient to package, store, transport and carry, simple and convenient in process and suitable for industrial production.

Description

Technical field [0001] The invention belongs to the technical field of pet medicine, and specifically relates to a sugar-free clindamycin granule for dogs and cats and a preparation method thereof. Background technique [0002] Clindamycin, also known as clindamycin, is a derivative obtained by replacing the hydroxyl group at the 7 position of lincomycin with chlorine. Clindamycin is antibacterial against many Gram-positive aerobes (excluding Enterococcus), Streptococcus (including pneumococcus), Bacillus (including Diphtheria), and certain Staphylococcus species (including penicillinase-producing strains) active. It is also active against many anaerobic bacilli, chlamydia, mycoplasma, plasmodium and toxoplasma. The antibacterial mechanism of clindamycin is similar to that of macrolide antibiotics. It acts on the 50S subunit of the bacterial ribosome and inhibits the synthesis of bacterial protein by inhibiting the elongation of the peptide chain, thereby removing the A protein...

AI Technical Summary

Problems solved by technology

[0006] The object of the present invention is to provide a kind of clindamycin sugar-free granules for the treatment of skin infection (wound, abscess), deep infection and tooth infection of dogs and cats and osteomyelitis of dogs, which solves the problem of clindamycin sugar-free granules existing in the market. Clindamycin oral drops as the main drug has the disadvantages of poor palatability and inconvenient transportation and storage. The granules are soluble granules with good palatability, high bioavailability, and are safe and convenient to use

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