Systems and methods for biological adaptive radiotherapy

Abstract

Disclosed herein are systems and methods for adapting and/or updating radiotherapy treatment plans based on biological and/or physiological data and/or anatomical data extracted or calculated from imaging data acquired in real-time (e.g., during a treatment session). Functional imaging data acquired at the time of radiation treatment is used to modify a treatment plan and/or dose delivery instructions to provide a prescribed dose distribution to patient target regions. Also disclosed herein are methods for evaluating treatment plans based on imaging data acquired in real-time.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application No. 62 / 523,691, filed June 22, 2017, the entire disclosure of which is hereby incorporated by reference. technical field [0003] Adaptive adjustment and / or anatomical data during a treatment session based on biological and / or physiological data and / or anatomical data extracted or calculated from imaging data acquired in real-time (eg, at the time of treatment) is disclosed herein. Or systems and methods for updating radiation therapy treatment planning and / or radiation delivery. Also disclosed herein are methods for evaluating a treatment plan based on real-time acquired imaging data. Background technique [0004] Radiation therapy treatment planning typically precedes treatment sessions (eg, weeks, days, hours). Thus, in the time period between the treatment planning session and the treatment session, various parameters may have changed, and th...

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Thus, in the time period between the treatment planning session and the treatment session, various parameters may have changed, and these

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