Mass spectrometer and optical system thereof

An optical system and mass spectrometer technology, applied in the field of mass spectrometry, to achieve the effects of convenient use, short pulse time and stable structure

Pending Publication Date: 2020-03-31
广州禾信康源医疗科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Based on this, it is necessary to provide a mass spectrometer and its optical system to solve many problems existing in traditional mass spectrometers using N2 lasers

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  • Mass spectrometer and optical system thereof
  • Mass spectrometer and optical system thereof
  • Mass spectrometer and optical system thereof

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Embodiment Construction

[0029] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the associated drawings. Preferred embodiments of the invention are shown in the accompanying drawings. However, the present invention can be embodied in many different forms and is not limited to the embodiments described herein. On the contrary, these embodiments are provided to make the understanding of the disclosure of the present invention more thorough and comprehensive.

[0030] It should be noted that when an element is referred to as being “disposed on” another element, it may be directly on the other element or there may also be an intervening element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or intervening elements may also be present.

[0031] Unless otherwise defined, all technical and scientific terms used herein have the same meaning...

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Abstract

The invention relates to a mass spectrometer and an optical system thereof. The optical system adopts a mass spectrum ion source design based on a solid laser, has the advantages of long service life,short pulse time, small size, high repetition frequency and the like compared with an N2 laser, and is beneficial to improving the resolution of a mass spectrometer and reducing the maintenance frequency. Particularly, according to the optical system, a solid laser, a whole optical path system and a shell are completely fixed to an optical fixing platform, the optical path system is located in the shell, the structure is very stable, and installation and maintenance are convenient. During use, the size of a laser spot can be adjusted by adjusting the distance between a first focusing lens anda collimating lens, so that the invention is convenient to use.

Description

technical field [0001] The invention relates to the technical field of mass spectrometry, in particular to a mass spectrometer and its optical system. Background technique [0002] Matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOFMS) is a widely used biological mass spectrometer. It forms a co-crystal by mixing the sample to be analyzed with the matrix. When the laser irradiates the co-crystal, the matrix absorbs the energy of the laser, and then transfers the energy to the sample, causing the sample to undergo desorption and ionization processes. Particles from the ionization of the sample are accelerated by the electric field and eventually reach the detector of the time-of-flight mass spectrometer. The arrival time of different substances to the mass spectrometer detector is also different, so the molecular weight of ions can be accurately calculated according to the arrival time of different ions. This soft ionization mass spectrometry techni...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01J49/02H01S3/02H01S3/101H01S3/13
CPCH01J49/02H01S3/025H01S3/101H01S3/13
Inventor 喻佳俊洪义朱星高
Owner 广州禾信康源医疗科技有限公司
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