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Traditional Chinese medicine formula for solving nasal obstruction symptoms, traditional Chinese medicine spray preparation and preparation method of spray preparation

A technology for symptoms and preparations, applied in pharmaceutical formulations, medical preparations containing active ingredients, and aerosol delivery, etc., can solve problems such as side effects, high prices, and effects that need to be verified, and achieve the goal of relieving nasal congestion symptoms and reducing waste of resources. Effect

Inactive Publication Date: 2020-09-22
SICHUAN NEO GREEN PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The above-mentioned patents all record the traditional Chinese medicine formula that adopts the compatibility of various Chinese herbal medicines for the purpose of treating syndromes, but there are few reports on the traditional Chinese medicine formula for the purpose of treating a single symptom, and the market is often dominated by western medicine. High defect, patent document CN101337064A (a spray for treating nasal congestion, 2009.01.07) discloses a traditional Chinese medicine composed of Nepeta, Fangfeng, Angelica dahurica, Radix Aconiti, Dried Ginger, Xanthium, Xinyihua, Chaoziqin, etc. The spray composed of the formula can quickly improve the nasal congestion symptoms of colds and rhinitis, but it has not been clinically verified, and its effect remains to be verified

Method used

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  • Traditional Chinese medicine formula for solving nasal obstruction symptoms, traditional Chinese medicine spray preparation and preparation method of spray preparation
  • Traditional Chinese medicine formula for solving nasal obstruction symptoms, traditional Chinese medicine spray preparation and preparation method of spray preparation
  • Traditional Chinese medicine formula for solving nasal obstruction symptoms, traditional Chinese medicine spray preparation and preparation method of spray preparation

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Effect test

Embodiment 1

[0055] This embodiment relates to a formulation of a traditional Chinese medicine spray preparation for solving nasal congestion symptoms caused by various rhinitis and a method for preparing the oily spray preparation.

[0056] Take 100 parts of Fructus Xanthii, 120 parts of goose not eating grass, 5 parts of artificial musk, and 40 parts of borneol for compatibility, and prepare the oily spray preparation of the traditional Chinese medicine formula with the compatibility ratio, the steps are as follows:

[0057] (1) According to the compatibility ratio, take cocklebur and goose not herbivorous, crush and cut into coarse powder, pass through a 10-mesh pharmacopoeia sieve, take the sieved coarse powder, soak in 1.5L lettuce oil, stir evenly, Shake on a shaker for 6h, and then place it for 10h. Centrifuge at 4000 rpm for 10 minutes, take the supernatant, and set aside.

[0058] (2) Take a small amount of the supernatant obtained in step (1), heat it to 60°C, pour the borneol i...

Embodiment 2

[0061] This embodiment relates to a formulation of a traditional Chinese medicine spray preparation for solving nasal congestion symptoms caused by various rhinitis and a method for preparing the oily spray preparation.

[0062] Take 130 parts of cocklebur, 90 parts of goose not eating grass, 10 parts of artificial musk, and 40 parts of borneol for compatibility. The traditional Chinese medicine formula of this compatibility ratio is prepared for oily spray preparation. The steps are as follows:

[0063] (1) According to the compatibility ratio, take cocklebur and goose herbivore, crush them, cut them into coarse powder, pass through a 20-mesh pharmacopoeia sieve, take the sieved coarse powder, soak in 2.0L lettuce oil, stir evenly, Shake on a shaker for 8 hours, then place for 16 hours. Centrifuge at 5000 rpm for 10 minutes, take the supernatant, and set aside.

[0064] (2) Take a small amount of the supernatant liquid obtained in step (1), heat it to 80°C, pour the borneol ...

Embodiment 3

[0067] This embodiment relates to a formulation of a traditional Chinese medicine spray preparation for solving nasal congestion symptoms caused by various rhinitis and a method for preparing the oily spray preparation.

[0068] Take 100 parts of Fructus Xanthii, 100 parts of goose not eating grass, 5 parts of artificial musk, and 30 parts of borneol for compatibility, and prepare the oily spray preparation of the traditional Chinese medicine formula with the compatibility ratio, the steps are as follows:

[0069] (1) According to the compatibility ratio, take cocklebur and goose herbivore, crush them, cut them into coarse powder, pass through a 20-mesh pharmacopoeia sieve, take the sieved coarse powder, soak in 2.0L lettuce oil, stir evenly, Shake it on a shaker for 8 hours, and then place it for 15 hours. Centrifuge at 4000 rpm for 10 minutes, take the supernatant, and set aside.

[0070] (2) Take a small amount of the supernatant liquid obtained in step (1), heat it to 80°...

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Abstract

The invention discloses a traditional Chinese medicine formula for solving nasal obstruction symptoms, a traditional Chinese medicine spray preparation and a preparation method of the spray preparation. Siberian cocklebur fruits, centipeda minima, artificial musk and borneol are matched according to a formula ratio, and in the preparation process, raw rapeseed oil is used as a solvent, so that active ingredients in the components can be effectively extracted, are used for preparing oily / gel spray preparations and are specially used for relieving nasal obstruction symptoms caused by various kinds of rhinitis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine formula for solving nasal congestion symptoms, a traditional Chinese medicine spray preparation and a preparation method thereof, in particular to a traditional Chinese medicine formula, a traditional Chinese medicine spray preparation and a preparation method for alleviating nasal congestion symptoms caused by various rhinitis, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Rhinitis is an inflammatory disease of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. Its types include chronic rhinitis, acute rhinitis, drug-induced rhinitis, atrophic rhinitis, allergic Rhinitis, etc., usually manifested as nasal congestion, nasal discharge, decreased sense of smell, headache, dizziness, etc. [0003] With the continuous development of modern medicine, the basic theory of tradit...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61K9/12A61P11/02A61K35/55A61K31/045
CPCA61K9/0043A61K9/12A61K31/045A61K35/55A61K36/28A61P11/02A61K2300/00
Inventor 周厚成胡昌江黄宇
Owner SICHUAN NEO GREEN PHARMA TECH DEV
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