Novel oral rehydration salt powder and preparation method thereof

A rehydration salt and a new type of technology, applied in the field of medicine, can solve the problems of reducing the amount of defecation, shortening the time of diarrhea, and unable to effectively improve the intestinal environment, and achieve the effects of reducing the amount of defecation, shortening the time of diarrhea, and enhancing the repair function of the gastrointestinal tract.

Pending Publication Date: 2020-09-25
福州华为医药技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The third-generation oral rehydration salts mainly contain glucose, which can correct and prevent the water shortage caused by diarrhea, but cannot effectively improve the intestinal environment, shorten the duration of diarrhea or reduce the amount of defecation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0016] The present invention provides a kind of preparation method of novel oral rehydration salt powder, comprising the following steps:

[0017] Step 1, the dried trehalose and burdock root freeze-dried powder, pulverized, passed through 80-100 mesh sieve, set aside;

[0018] Step 2. Grinding the dried sodium chloride, potassium chloride, sodium citrate and anhydrous glucose into powders with a particle size of less than 40 mesh and 8-15% of particles with a particle size of less than 120 mesh;

[0019] Step 3: Add 18.20-20.33 parts by weight of anhydrous glucose, 17.08-17.94 parts by weight of burdock root freeze-dried powder, and 6.98-7.25 parts by weight of sodium citrate into the multidirectional motion mixer in sequence , 6.2-6.5 parts by weight of sodium chloride, 5.5-6.2 parts by weight of trehalose, and 3.58-3.75 parts by weight of potassium chloride, are mixed to obtain a mixture.

[0020] It can be seen from the above description that the beneficial effect of the ...

Embodiment 1

[0025] A new type of oral rehydration salt powder, composed of 0.64g of sodium chloride, 0.347g of potassium chloride, 0.713g of sodium citrate, 1.975g of anhydrous glucose, 0.56g of trehalose and 1.765g of burdock root jelly dry powder composition.

Embodiment 2

[0027] A preparation method of novel oral rehydration salt powder, specifically comprising the following steps:

[0028] Step 1, drying (drying) the freeze-dried powder of trehalose and burdock root until the water content is lower than 0.5%, crushing the dried freeze-dried powder of trehalose and burdock root, passing through a 80-100 mesh sieve, and setting aside;

[0029] Step 2, drying (drying) sodium chloride, potassium chloride, sodium citrate and anhydrous glucose to a water content lower than 0.5%, drying sodium chloride, potassium chloride, sodium citrate and Dextrose anhydrous, respectively pulverized into a powder with a particle size of less than 40 mesh and particles with a particle size of less than 120 mesh accounting for about 10%;

[0030] Step 3. Add 182g of anhydrous glucose, 179.4g of burdock root freeze-dried powder, 69.8g of sodium citrate, 62g of sodium chloride, 62g of trehalose, Potassium chloride 35.8g, after mixing for 40min, the mixture was obtaine...

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Abstract

The invention discloses a novel oral rehydration salt powder and a preparation method thereof, and belongs to the technical field of medicine. The novel oral rehydration salt powder comprises the following components in parts by weight: 6.2 to 6.5 parts of sodium chloride, 3.58 to 3.75 parts of potassium chloride, 6.98 to 7.25 parts of sodium citrate, 18.20 to 20.33 parts of anhydrous dextrose, 5.5 to 6.2 parts of trehalose and 17.08 to 17.94 parts of burdock root freeze-dried powder. The novel oral rehydration salt powder not only can relieve the mild and moderate dehydration problem caused by diarrhea, but also can effectively shorten the diarrhea time, reduce the defecation amount and enhance the gastrointestinal repair function, and is beneficial to accelerating the rehabilitation of diarrhea patients. According to the preparation method of the novel oral rehydration salt powder, the fluidity of a mixture can be remarkably improved, and the mixing uniformity and good solubility ofthe obtained powder are guaranteed.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a novel oral rehydration salt powder and a preparation method thereof. Background technique [0002] Oral Rehydration Salts (ORS) has been recommended by the World Health Organization (WHO) for the treatment of mild to moderate dehydration caused by acute diarrhea since the 1970s. For more than 40 years, oral rehydration salts have been widely used around the world, greatly reducing the mortality rate of acute diarrhea and saving the lives of millions of diarrhea patients in developing countries. Named the greatest medical advance of the 20th century. Clinical application and practice summary found that oral rehydration salts Ⅰ and Ⅱ have obvious effects in correcting dehydration, but they have obvious shortcomings in curative effect and safety. , announced the hypotonic formulation of oral rehydration salts in 2002; on March 23, 2006, it officially issued a docume...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61K9/14A61P1/12A61P1/00A61K33/14A61K31/194A61K31/7004A61K31/7016
CPCA61K9/14A61K31/194A61K31/7004A61K31/7016A61K33/14A61K36/28A61P1/00A61P1/12A61K2300/00
Inventor张娜蔡燕峰李小玲符友伟谢治平林健勇叶燕军张会会
Owner福州华为医药技术开发有限公司