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Capture device and capture catheter for capturing target object by adopting immunomagnetic adsorption principle

A technology for capturing devices and targets, applied in trocars, filters in blood vessels, surgery, etc., can solve the problem of small number of circulating tumor cells, and achieve the effect of convenient operation and large capture range

Pending Publication Date: 2020-10-16
蒋霆辉 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a capture device and a capture catheter that use the principle of immunomagnetic adsorption to capture target objects in vivo, so as to improve the problem that the number of circulating tumor cells obtained by using existing products is too small

Method used

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  • Capture device and capture catheter for capturing target object by adopting immunomagnetic adsorption principle
  • Capture device and capture catheter for capturing target object by adopting immunomagnetic adsorption principle
  • Capture device and capture catheter for capturing target object by adopting immunomagnetic adsorption principle

Examples

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Embodiment 1

[0047] The steps in Example 1 can be adjusted in actual operation. The operation of the capture device of the present invention is not limited to the following methods.

[0048] Take the case of inferior vena cava capture.

[0049] 1. Capture basket in place

[0050] After disinfecting the groin with drape and local anesthesia, the femoral vein was punctured and inserted into the catheter sheath, and the ordinary ultra-smooth guide wire and guide catheter were guided up to the hepatic vein segment of the inferior vena cava under the guidance of fluoroscopy, and DSA angiography was performed to clarify the vessel diameter and Select a magnetic capture basket (Interventional Magnetic Collecting Basket, IMCB) of different specifications, insert it into the blood vessel and flush the tube with heparin.

[0051] 2. Capture process

[0052] Intravenous infusion of immunomagnetic adsorbent. 5 ~ 10min retreat the overtube 2 to open the IMCB. Perspectively observe the opening stat...

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Abstract

The invention discloses a capture device and a capture catheter for capturing a target object by adopting an immunomagnetic adsorption principle. The capture device comprises an immunomagnetic adsorbent combined with the target object and the capture catheter for adsorbing the target object combined with the immunomagnetic adsorbent; the capturing catheter comprises a magnetic capturing basket, anouter sleeve, a guide wire and a control part, wherein the magnetic capture basket comprises 2-15 magnetic capture wires; and after the magnetic capture wires extend out of the outer sleeve, the magnetic capture wires are automatically expanded and are basically arranged at equal intervals, so that the magnetic capture basket is fusiform. The invention further provides the capture catheter in thecapture device. The invention further provides a capture catheter which is provided with a single capture wire with magnetism, the initial shape of the capture catheter is spiral or wavy, and the capture wire can be stretched so as to be contained in the outer sleeve. The capture catheter has a relatively large capture cross section, and more targets in blood or body fluid can be obtained.

Description

technical field [0001] The invention relates to the technical field of medical devices and the field of liquid biopsy, in particular to a capture device and a capture catheter which adopt the principle of immunomagnetic adsorption to capture target objects. Background technique [0002] The metastasis of cancer is largely due to the transfer of cancer cells from the primary tumor to other organs through the blood, forming new metastatic tumors. At present, a large number of cancer-related studies are based on this kind of abnormal cells with metastatic potential: Circulating Tumor Cells (CTCs). The abnormal cells captured and detected have been used in liquid diagnostic methods. Through the detection of such abnormal cells, more information related to metastasis can be obtained, and at the same time, the direction of cancer metastasis can be tracked and the prognosis of treatment can be predicted. Secondly, there are still many difficulties in tumor biopsy that cannot be co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/01A61B10/02
CPCA61B10/02A61F2/01A61F2002/016
Inventor 蒋霆辉梁晓飞蒋世成宋萍陆珺刘艳李秋营
Owner 蒋霆辉
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