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A traditional Chinese medicine composition with smoking cessation effect and its preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems such as low long-term withdrawal rate of auricular point sticking, uncertain efficacy of traditional Chinese medicine tea, long-time decoction, etc., and achieve the relief of respiratory problems, the exact effect of smoking cessation, and the curative effect. Enhanced effect

Active Publication Date: 2022-06-07
LUNAN HOPE PHARM CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some problems in traditional Chinese medicine smoking cessation therapy, such as acupuncture has a certain pain, traditional Chinese medicine decoction needs to be boiled for a long time, the long-term withdrawal rate of auricular point sticking is not high, and the curative effect of traditional Chinese medicine tea is not sure, so it needs to be continued. Explore scientifically reasonable, painless and efficient traditional Chinese medicine smoking cessation therapy

Method used

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  • A traditional Chinese medicine composition with smoking cessation effect and its preparation method and application
  • A traditional Chinese medicine composition with smoking cessation effect and its preparation method and application
  • A traditional Chinese medicine composition with smoking cessation effect and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The preparation of embodiment 1 smoking cessation tablet

[0037] Saponin 0.1kg Zhe Fritillaria 0.8kg

[0038] Mulberry white peel 1.2kg Bellflower 1.1kg

[0039] A. Weigh 4 kinds of raw medicinal materials of saponin, fritillary, mulberry white peel and platycodon grandiflorum, among which, platycodon grandiflorum is cleaned and cut into sections, mulberry white peel is cleaned and shredded, and fritillary is cleaned, coarsely chopped, saponin Clean selection, pulverize at low temperature into fine powder of saponin with an average particle size of less than 240μm, sieve, and set aside;

[0040]B. Take 3 kinds of raw medicinal materials, such as fritillary fritillary, mulberry white peel and platycodon grandiflorum, add 10 times the amount of water, decocted for 2 times, decocted for 1.5 hours each time, filter, combine the filtrates, and concentrate under reduced pressure to 60-70 ℃ The extract with a relative density of 1.22 was dried in a vacuum belt dryer, the va...

Embodiment 2

[0042] Example 2 Preparation of Quit Smoking Granules

[0043] Saponin 0.25kg Zhe Fritillaria 1.05kg

[0044] Mulberry white peel 0.95kg Bellflower 0.85kg

[0045] A. Weigh 4 kinds of raw medicinal materials of saponin, fritillary, mulberry white peel and platycodon grandiflorum, among which, platycodon grandiflorum is cleaned and cut into sections, mulberry white peel is cleaned and shredded, and fritillary is cleaned, coarsely chopped, saponin Clean selection, pulverize at low temperature into fine powder of saponin with an average particle size of less than 230μm, sieve it for later use;

[0046] B. Take 3 kinds of raw medicinal materials of Fritillaria, mulberry white peel and Platycodon grandiflorum, add 8 times the amount of water, decocted for 2 times, decocted for 2 hours each time, filter, combine the filtrates, and concentrate under reduced pressure to 60-70 ℃ The extract with a relative density of 1.17 was dried in a vacuum belt dryer, the degree of vacuum was -0....

Embodiment 3

[0048] Example 3 Preparation of Quit Smoking Capsules

[0049] Saponin 0.20kg Fritillaria 1kg

[0050] Mulberry white peel 1kg, Bellflower 0.9kg

[0051] A. Weigh 4 kinds of raw medicinal materials of saponin, fritillary, mulberry white peel and platycodon grandiflorum, among which, platycodon grandiflorum is cleaned and cut into sections, mulberry white peel is cleaned and shredded, and fritillary is cleaned, coarsely chopped, saponin Clean selection, pulverize at low temperature into fine powder of saponin with an average particle size of less than 220 μm, sieve it for later use;

[0052] B. Take 3 kinds of raw medicinal materials, such as Fritillaria, mulberry white peel and Platycodon grandiflorum, add 9 times the amount of water, decocted for 2 times, decocted for 1.5 hours each time, filter, combine the filtrates, and concentrate under reduced pressure to 60-70 ℃ The extract with a relative density of 1.21 was dried in a vacuum belt dryer, the vacuum degree was -0.09Mp...

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Abstract

The invention provides a traditional Chinese medicine composition with the effect of smoking cessation and a preparation method thereof. The traditional Chinese medicine composition is prepared from four raw materials of saponins, fritillary fritillaria, cortex mulberry and platycodon grandiflorum. Pharmacodynamic test results show that the Chinese medicine composition of the present invention can significantly alleviate the respiratory inflammation of smoking model rats by reducing the content of airway inflammatory factors TNF-α, IL-6, and IL-1β, and has obvious effect on smoking rats simultaneously. expectorant effect. Clinical observations show that the traditional Chinese medicine composition of the present invention has a significant smoking cessation effect, which makes patients feel disgusted by the smell of cigarettes and thus completely gives up smoking. At the same time, it can significantly alleviate the patient's respiratory problems and lighten withdrawal symptoms. It is accurate and safe, and suitable for long-term use.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicinal composition with smoking cessation effect and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] China is the largest tobacco producer and consumer in the world. On average, more than 1 million people die each year from tobacco-related diseases. Tobacco has become the most preventable risk factor for Chinese deaths. At present, the number of smokers in my country is about 350 million, and the passive smoking rate of the population is relatively high. Tobacco use causes huge economic and social burdens. Therefore, how to effectively prevent tobacco harm has become a public health problem that needs to be solved urgently. At present, many countries around the world are making progress in reducing smoking. Many countries have passed legislation, increas...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8966A61P25/34A61P11/00A61P11/10
CPCA61K36/483A61K36/8966A61K36/605A61K36/346A61K9/0053A61P25/34A61P11/00A61P11/10A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00Y02A50/30
Inventor 严冬钱玉良严正仲严士海常钰
Owner LUNAN HOPE PHARM CO LTD