Free space type Mueller OCT imaging system for full-automatic time division detection and imaging method

A free space, imaging system technology, applied in the fields of biomedicine and optics, can solve the problems of reducing experimental efficiency, unable to fully describe the polarization characteristics of biological samples, manually adjusting the scale error, etc., to achieve the effect of improving the acquisition rate

A free space, imaging system technology, applied in the fields of biomedicine and optics, can solve the problems of reducing experimental efficiency, unable to fully describe the polarization characteristics of biological samples, manually adjusting the scale error, etc., to achieve the effect of improving the acquisition rate

CN112147080APending Publication Date: 2020-12-29FUJIAN NORMAL UNIV

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  • Free space type Mueller OCT imaging system for full-automatic time division detection and imaging method

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Embodiment Construction

[0031] In order to make the purpose, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application.

[0032] Such as figure 1As shown, the present invention discloses a free-space Mueller OCT imaging system of fully automatic time-division detection, which includes: a low-coherence broadband polarized light source 1, a first collimator mirror 2, a first non-polarization beam splitter 3, a second non-polarization Beam splitter 4, third non-polarizing beam splitter 5, first aperture 6, first optical switch 7, first mirror 8, second aperture 9, second optical switch 10, first quarter Wave plate 11, second mirror 12, fourth non-polarizing beam splitter 13, third aperture 14, third optical switch 15, second quarter wave plate 16, third mirror 17, fourth optical ...

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Abstract

The invention discloses a free space type Mueller OCT imaging system for full-automatic time division detection and an imaging method. Four optical channels with different polarization types, namely horizontal type, vertical type, 45-degree linear polarization type and right-handed circular polarization type, are arranged in a reference wall, and meanwhile, a sample wall realizes polarized light of the four states by using a software program to control a rotating wave plate of a precision rotating worktable; a software program is also used in the reference wall to control an optical switch toselect different channels in the reference wall, and polarized light of the channels returns to interfere with the polarized light scattered by the sample wall correspondingly, so that time division detection of polarization information is realized; and meanwhile, 16 element images of a Mueller matrix of a sample are reconstructed, so that the collection of complete polarization information is realized. According to the free space type Mueller OCT imaging system for full-automatic time division detection and the imaging method, full-automatic control is realized, image acquisition can be rapidly carried out, and the sampling rate is improved.

Description

technical field [0001] The invention relates to the fields of biomedicine and optics, in particular to a free-space Mueller OCT imaging system and an imaging method for full-automatic time-division detection. Background technique [0002] At present, biological imaging technologies mainly include: ultrasound imaging, X-ray imaging, magnetic resonance diffusion imaging technology and optical coherence tomography technology. Among them, ultrasonic imaging, X-ray imaging and other methods are easy to cause deformation to the tissue, and will damage the tissue structure. The imaging resolution of the tissue structure is not high, and it is impossible to observe the tiny structure in the tissue. The new optical coherence tomography technology is With the advantages of no damage and high resolution, it can perfectly image the tissue microstructure, especially a new polarized optical coherence tomography technology developed by the Mueller OCT imaging system on the basis of traditi...

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Application Information

Patent Timeline
29 Dec 2020
Publication
CN112147080A
IPC
G01N21/21; G01N21/01
CPC
G01N21/21; G01N21/01; G01N2021/216
Inventors
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