Ultrasonic non-invasive transcranial imaging method and system based on broadband acoustic metamaterials

Abstract

The invention relates to an ultrasonic noninvasive transcranial imaging method and system based on broadband acoustic metamaterials. The method includes obtaining reflection signals corresponding to different combinations of acoustic metamaterial parameters and the skull as a whole; determining the combination of acoustic metamaterial parameters to be determined according to the reflection signals to be determined and the trained three-layer BP neural network; judging Whether the combination of acoustic metamaterial parameters to be determined is in the threshold space; if so, use the combination of acoustic metamaterial parameters to be determined to prepare acoustic metamaterials; perform ultrasonic non-invasive transcranial imaging on the resolution mold; if not, re- Make sure. The invention enhances the penetrating effect of sound waves on the skull to realize ultrasonic non-invasive transcranial imaging.

Description

technical field [0001] The invention relates to the field of brain imaging, in particular to an ultrasonic noninvasive transcranial imaging method and system based on broadband acoustic metamaterials. Background technique [0002] Because the skull has a strong attenuation and distortion effect on ultrasound, it is difficult for existing ultrasound imaging theories to effectively penetrate various parts of the skull to achieve intracranial tissue and blood flow imaging (hereinafter referred to as transcranial ultrasound imaging). In recent years, world-renowned research institutions such as Harvard University, the Massachusetts Institute of Technology, and the French Langevin Institute have successively carried out frontier explorations of transcranial ultrasound imaging: in 2014, Shen et al. proposed the design idea of ​​a new type of transcranial ultrasound metamaterial; In 2015, Cai et al. proposed a general method for making underwater metamaterials using 3D printing, wh...

AI Technical Summary

Problems solved by technology

However, affected by many factors such as the strong distortion effect of the skull on sound waves and the unknown mechanism of acoustic metamaterials, the transcranial ultrasound brain imaging system is still in the stage of theoretical exploration and most of them are invasive transcranial imaging.

Images