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Application of herba schizonepetae-radix saposhnikoviae preparation in preparation of gastric ulcer treatment medicines and preparation method of herba schizonepetae-radix saposhnikoviae preparation

A gastric ulcer and preparation technology, which is applied to the application of Jingfang preparations in the preparation of medicines for treating gastric ulcers and the field of preparation thereof, can solve the problems of insignificant effects, adverse reactions, complex components and the like

Inactive Publication Date: 2021-02-12
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, the traditional Chinese medicine treatment of gastric ulcer has gradually attracted people's attention and attention. However, the traditional Chinese medicine preparations currently on the market for the treatment of gastric ulcer have complex ingredients, many adverse reactions, and the effect is not obvious.

Method used

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  • Application of herba schizonepetae-radix saposhnikoviae preparation in preparation of gastric ulcer treatment medicines and preparation method of herba schizonepetae-radix saposhnikoviae preparation
  • Application of herba schizonepetae-radix saposhnikoviae preparation in preparation of gastric ulcer treatment medicines and preparation method of herba schizonepetae-radix saposhnikoviae preparation
  • Application of herba schizonepetae-radix saposhnikoviae preparation in preparation of gastric ulcer treatment medicines and preparation method of herba schizonepetae-radix saposhnikoviae preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] The preparation of embodiment 1 Jingfang capsule

[0086]

[0087]

[0088] A. Nepeta, Fangfeng, Notopterygium, Duhuo, Peucedanum, Chuanxiong and Citrus aurantium were extracted to obtain volatile oils of 7 kinds of medicinal materials, and the distilled medicinal residues, Chuanxiong and Citrus aurantium distilled aqueous solution were used for later use;

[0089] B. Get the volatile oil gained in step A, add β-cyclodextrin respectively to make clathrate;

[0090] C. the distilled aqueous solution of Rhizoma Chuanxiong and Fructus Fructus Fructus obtained in step A is made into 29% ethanol solution as solvent, and the medicinal residues of Rhizoma Chuanxiong and Fructus Fructus Fructus Fructus obtained in step A are percolated with Poria cocos to obtain percolation liquid for subsequent use;

[0091] D. Add the dregs of Schizonepeta, Fangfeng, Notopterygium, Duhuo and Peucedanum obtained in step A, and the rest of Bupleurum, Campanulaceae, Licorice and other thre...

Embodiment 2

[0094] The preparation of embodiment 2 Jingfang tablets

[0095]

[0096] A. Nepeta, Fangfeng, Notopterygium, Duhuo, Peucedanum, Chuanxiong and Citrus aurantium were extracted to obtain volatile oils of 7 kinds of medicinal materials, and the distilled medicinal residues, Chuanxiong and Citrus aurantium distilled aqueous solution were used for later use;

[0097] B. Get the volatile oil gained in step A, add β-cyclodextrin respectively to make clathrate;

[0098] C. the distilled aqueous solution of Rhizoma Chuanxiong and Fructus Aurantii obtained in step A is made into 22% ethanol solution as a solvent, and the medicinal residues of Rhizoma Chuanxiong and Fructus Fructus Fructus obtained in step A are percolated with Poria cocos to obtain percolation liquid for subsequent use;

[0099] D. Decoct the medicinal residues of Schizonepeta, Fangfeng, Notopterygium, Duhuo and Peucedanum obtained in step A with the rest of Bupleurum, Campanulaceae, Licorice and other three flavors...

Embodiment 3

[0102] The preparation of embodiment 3 Jingfang capsules

[0103]

[0104] A. Nepeta, Fangfeng, Notopterygium, Duhuo, Peucedanum, Chuanxiong and Citrus aurantium were extracted to obtain volatile oils of 7 kinds of medicinal materials, and the distilled medicinal residues, Chuanxiong and Citrus aurantium distilled aqueous solution were used for later use;

[0105] B. Get the volatile oil gained in step A, add β-cyclodextrin respectively to make clathrate;

[0106] C. the distilled aqueous solution of Rhizoma Chuanxiong and Fructus Aurantii obtained in step A is made into 26% ethanol solution as a solvent, and the medicinal residues of Rhizoma Chuanxiong and Fructus Fructus Fructus obtained in step A are percolated with Poria cocos to obtain percolation liquid for subsequent use;

[0107] D. Decoct the medicinal residues of Schizonepeta, Fangfeng, Notopterygium, Duhuo and Peucedanum obtained in step A with the rest of Bupleurum, Platycodon grandiflora, and licorice, and deco...

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Abstract

The invention discloses an application of a herba schizonepetae-radix saposhnikoviae preparation in preparation of gastric ulcer treatment medicines and a preparation method of the herba schizonepetae-radix saposhnikoviae preparation, and belongs to the field of medicines. The herba schizonepetae-radix saposhnikoviae preparation is prepared from 11 raw medicinal materials including herba schizonepetae, radix saposhnikoviae, notopterygium root, doubleteeth pubescent angelica root, Chinese thorowax root, common hogfenneI root, szechuan lovage rhizome, fructus aurantii, poria cocos, platycodon grandiflorum and liquoric root and has the effects of inducing sweat, dispelling exogenous evils, dispelling wind and eliminating dampness. The herba schizonepetae-radix saposhnikoviae preparation can effectively treat stress gastric ulcer and acetic acid induced chronic gastric ulcer, inhibit gastric acid secretion and reduce free acid and total acidity in gastric juice, has the effect of reducingpepsase activity, treats both symptoms and root causes, and has an exact treatment effect on gastric ulcer.

Description

technical field [0001] The invention relates to the application of Jingfang preparation and its preparation method, in particular to the application of Jingfang preparation in the preparation of medicine for treating gastric ulcer and its preparation method, belonging to the field of traditional Chinese medicine. Background technique [0002] Gastric ulcer (Gastric Ulcer) is a type of peptic ulcer, specifically referring to ulcers that occur in the gastric angle, gastric antrum, cardia, and hiatal hernia. Compared with other peptic ulcers, gastric ulcers have more clinical symptoms, with chronic, periodic, and rhythmic postprandial mid- and upper-abdominal pain as typical symptoms, which may also be accompanied by indigestion, nausea, vomiting, belching, and other related digestive symptoms. tract symptoms. In the pathogenesis of gastric ulcer, Helicobacter pylori infection is the main cause of gastric ulcer, and mucosal autodigestion caused by gastric acid and pepsin is th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/16A61K9/50A61K47/36A61K47/42A61K47/69A61P1/04
CPCA61K9/1652A61K9/5052A61K36/076A61K36/23A61K36/232A61K36/233A61K36/236A61K36/237A61K36/238A61K36/346A61K36/484A61K36/538A61K36/752A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K47/6951A61P1/04A61K2300/00
Inventor 关永霞邵明杰杜昊忱郝大伟
Owner LUNAN PHARMA GROUP CORPORATION
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