Biodegradable magnetic control PVA micro-motor stent and preparation method and use of biodegradable magnetic control PVA micro-motor stent
A magnetic control and product technology, applied in the fields of pharmaceutical formulation, drug delivery, medical science, etc., can solve the problems of insufficient biocompatibility of vascular stents, reduce the effectiveness of treatment, and vascular restenosis, etc., and achieve the inhibition of adverse reactions of intimal hyperplasia , Simplify the adjustment process and implantation process, and the effect of high movement rate
Active Publication Date: 2021-03-05
SUN YAT SEN UNIV
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Problems solved by technology
[0003] Vascular stent implantation is an effective medical intervention for the treatment of vascular stenosis-related diseases. However, in the prior art, vascular stents prepared from traditional materials have problems such as insufficient biocompatibility and the need to introduce additional shape expansion devices. Moreover, in order to ensure The accuracy of implantation requires highly invasive treatment methods, and the existence of these problems can easily cause restenosis and arterial damage, thereby reducing the effectiveness of treatment
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[0045] In order to make the object, technical solution and technical effect of the present invention clearer, the present invention will be further described in detail below in conjunction with specific embodiments. It should be understood that the specific implementations described in this specification are only for explaining the present invention, not for limiting the present invention.
[0046] The experimental materials and reagents used, unless otherwise specified, are conventional consumables and reagents that can be obtained from commercial channels.
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Abstract
The invention discloses a biodegradable magnetic control PVA micro-motor stent and a preparation method and use of the biodegradable magnetic control PVA micro-motor stent. A magnetic control PVA material is obtained by mixing and cross-linking polyvinyl alcohol, magnetic particles, a cross-linking agent and water. An intravascular stent prepared from the material can adopt ultrasonic waves to trigger shape memory, an adjusting process and an implantation process of a material formula can be simplified in cooperation with a movement performance of a magnetic drive motor, the intravascular stent is controlled to move in vivo to reach a target position, a fixed-point implantation is not needed, invasiveness and implantation risks are further reduced, and the stent better meets actual application requirements.
Description
technical field [0001] The invention belongs to the field of biological materials, and in particular relates to a biodegradable magnetically controlled PVA micro-motor support and a preparation method and application thereof. Background technique [0002] Micromotor is an artificial power device with excellent motion performance and precise navigation performance. It has broad application prospects in the biomedical field. In order to make micromotors more widely used in biomedical fields, improve the performance of micromotor systems Biocompatibility has important research significance. [0003] Vascular stent implantation is an effective medical intervention for the treatment of vascular stenosis-related diseases. However, in the prior art, vascular stents prepared from traditional materials have problems such as insufficient biocompatibility and the need to introduce additional shape expansion devices. Moreover, in order to ensure The accuracy of implantation requires hi...
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IPC IPC(8): A61L31/14A61L31/04A61L31/02C08J3/075C08J3/24C08L29/04C08K5/3492C08K3/22
CPCA61L31/145A61L31/048A61L31/14A61L31/028C08J3/075C08J3/24C08J2329/04C08K5/34922C08K2201/011C08K2003/2275C08K2201/01A61L2400/12A61L2400/16C08L29/04
Inventor 彭飞苏沛锋覃枫莹王珍
Owner SUN YAT SEN UNIV




