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Traditional Chinese medicine composition for treating scleroderma and its preparation method and application

A composition and technology of scleroderma, applied in the field of medicine, can solve problems such as ineffective effects

Active Publication Date: 2022-05-17
厦门市中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of Western medicine treatment, the use of immunosuppressants (such as methotrexate, cyclophosphamide, etc.), glucocorticoids and anti-fibrosis (such as penicillamine, colchicine, pirfenidone, etc.) is an important treatment method. Although there are a variety of immunosuppressants and drugs with potential effects that can be used for anti-fibrosis, there is no recognized effective drug, especially in improving skin sclerosis
The treatment of modern western medicine needs to be further improved in terms of economic pressure, potential side effects, and drug failure of patients with scleroderma

Method used

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  • Traditional Chinese medicine composition for treating scleroderma and its preparation method and application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]The traditional Chinese medicine composition for the treatment of scleroderma of the present embodiment, the raw materials include: ephedra 4g, aconite (decocted first) 12g, asarum 5g, rhubarb (wine) 3g, turmeric 10g, cicada slough 5g, silkworm 10g, Coix seed 40g, Centella asiatica 40g.

[0032] First put the aconite in the special casserole for decoction of traditional Chinese medicine and boil it for 30 minutes, then boil it together with the rest of the medicinal materials until it boils, and then simmer for 30 minutes, and filter out 200mL of medicinal liquid; Add water to the medicinal liquid again to about 2-3 cm above the medicinal residues, boil with high heat and decocted with low heat until the medicinal liquid is 150 mL, and mix the two filtered medicinal liquids. 1 dose a day, in the morning and evening after meals.

Embodiment 2

[0034] The traditional Chinese medicine composition for the treatment of scleroderma of the present embodiment, the raw materials include: ephedra 3g, aconite (decocted first) 14g, asarum 5g, rhubarb (wine) 3g, turmeric 10g, cicada slough 5g, silkworm 10g, Coix seed 40g, Centella asiatica 50g.

[0035] The preparation method and the taking method refer to Example 1.

Embodiment 3

[0037] The traditional Chinese medicine composition for the treatment of scleroderma of the present embodiment, the raw materials include: ephedra 4g, aconite (decocted first) 12g, asarum 5g, rhubarb (wine) 3g, turmeric 10g, cicada slough 5g, silkworm 10g, Coix seed 50g, Centella asiatica 45g.

[0038] The preparation method and the taking method refer to Example 1.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating scleroderma, a preparation method and application thereof. The raw materials of the traditional Chinese medicine composition include ephedra, aconite, asarum, rhubarb (made from wine), turmeric, cicada slough, silkworm, coix seed, centella asiatica and the like. The present invention uses the idea of ​​syndrome differentiation and treatment in traditional Chinese medicine, and combines the pathogenesis and etiology of scleroderma to provide an efficient and reliable Chinese medicine composition, which effectively solves the problem of medication for scleroderma, and improves the skin sclerosis of scleroderma and improves the treatment of scleroderma. The scheme provides an idea to improve the effective rate of scleroderma treatment.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating scleroderma. Background technique [0002] Scleroderma is a connective tissue disease characterized by focal or diffuse skin hardening or thickening that can also affect blood vessels and internal organs. It can be divided into systemic sclerosis and focal scleroderma according to the location of the lesion. The skin pathological changes are mainly collagen fibrils. Its pathogenesis has not yet been fully elucidated. Three points of pathogenesis are currently known: vascular injury and destruction, activation of the immune system, and extensive vascular and interstitial fibrosis. The disease is more common in women, with a male-to-female ratio of 1:(3-6), and it is more common between the ages of 30 and 50, and can also be seen in adolescents. The increased risk of multisystem damage is associated with a later age of onset, and s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K36/9068A61P37/02A61P17/00A61K35/64
CPCA61K36/17A61K36/714A61K36/268A61K36/708A61K36/9066A61K35/64A61K36/8994A61K36/23A61K36/232A61K36/236A61K36/487A61K36/9068A61P37/02A61P17/00A61K2236/331A61K2236/39A61K2300/00Y02A50/30
Inventor 邱明山陈进春杨燕婷张倩李依寒张怡燕陈静彭海聪
Owner 厦门市中医院