Angelica sinensis and astragalus membranaceus blood-enriching granules and preparation method thereof

Abstract

The invention discloses Angelica sinensis and astragalus membranaceus blood-enriching granules and a preparation method thereof. The preparation method comprises the following steps: (1) soaking radix astragali decoction pieces and wine radix angelicae sinensis in water, then carrying out reflux extraction, and collecting aromatic water in the extraction process, so as to obtain an extract solution and aromatic water; (2) concentrating the extract solution under reduced pressure to obtain a concentrated solution; (3) uniformly mixing the concentrated solution with aromatic water, and performing spray drying to obtain spray-dried powder; and (4) uniformly mixing the spray-dried powder with auxiliary materials, and performing dry granulation to obtain the angelica sinensis and astragalus membranaceus blood-enriching granules. The aromatic water is collected by adopting a condensing device in the extraction process, so that the volatilized ligustilide is retained, and the aromatic water is directly added back into the concentration device for drying and granulating, so that the loss of the volatile component ligustilide is avoided to a greater extent, the retention rate of the ligustilide is increased from 0-1% to more than 40%, and the quality of the ligustilide is improved. Effective utilization of water-soluble components and volatile components is effectively guaranteed, and it is guaranteed that the angelica sinensis and astragalus membranaceus blood-enriching soup granules effectively exert the clinical effect.

Description

technical field

[0001] The invention relates to the field of angelica blood-enriching preparations, in particular to an angelica-huangqi blood-enriching granule and a preparation method thereof. Background technique

[0002] Danggui Buxue Decoction comes from "Distinguishing Puzzles from Internal and External Injuries" written by Li Dongyuan, a famous doctor in the Jin Dynasty. It is composed of astragalus and angelica in a ratio of 5:1. Those who use it in combination can nourish both qi and blood. It is mainly used to treat fever due to blood deficiency. It has the functions of invigorating qi and generating blood and taking blood to reduce fever. It is a classic famous prescription for invigorating qi and generating blood. Modern clinical research has proved that Danggui Buxue Decoction can treat various types of anemia, menopausal syndrome, immune system disorders, cardiovascular and cerebrovascular system diseases, surgical orthopedic operations and postoperative compl...

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