69 results about "Astragalus verus" patented technology

The invention discloses an efficient extraction method of large-molecular-weight astragalus polysaccharide, which belongs to the technical field of plant extraction, and comprises the following steps: cleaning astragalus, filtering, and crushing; the preparation method comprises the following steps: mixing a beta-1, 3-glucanase aqueous solution and trehalose ethylene diamine, and stirring for 10-30 minutes to obtain an enzyme protection system; soaking the radix astragali powder in a citric acid solution, adding an enzyme protection system, applying a bipolar pulsed electric field, and reacting at 40-60 DEG C for 30-40 minutes; adjusting the concentration of the ethanol to 40-50%, standing, centrifuging and collecting crude astragalus polysaccharide; purifying, decolorizing, concentrating, freeze-drying and crushing the crude astragalus polysaccharide to obtain refined astragalus polysaccharide; the mass ratio of the trehalose ethylene diamine to the beta-1, 3-glucanase is (15: 1) to (30: 1). The enzyme protection system maintains the activity of the enzyme, the enzyme and the pulsed electric field act synergistically, the extraction time is shortened, and the extraction rate is increased while the astragalus polysaccharide with large molecular weight is obtained.

The present application relates to the field of microbiological technology, and particularly relates to a pathogenic bacterium causing root rot symptoms of red heart disease of Astragalus membranaceus and application thereof, the pathogenic bacterium is Fusarium sp. Fusarium sp. FUS-001-2025, preserved in China General Microbiological Culture Collection Center on March 16, 2026, with the preservation number of CGMCC No. 42529; it is determined to be a new recorded strain of Fusarium sp. through morphological and molecular identification, and the bactericide sensitivity determination shows that 25% silthiofam·prochloraz has the strongest inhibition effect, 25% bromothalonil, 50% azoxystrobin and 70% methylthiophanate have significant inhibition at high concentrations. The present application provides an important pathogenic bacterium resource for the pathogenic mechanism, disease resistance evaluation and development of control agents of red heart disease of Astragalus membranaceus.

The present application relates to the technical field of polysaccharide modification, and specifically discloses amino acid modified astragalus polysaccharide, a preparation method thereof and antibacterial application. The present application uses astragalus polysaccharide, formaldehyde and specific amino acids as raw materials, and prepares amino acid grafted modified astragalus polysaccharide through a Mannich reaction. The amino acid grafting site only occurs on the fifth carbon of the sugar ring. Not only does this retain the amino and carboxyl groups of the amino acid, so that the biological activity of the amino acid is retained, but also the active carboxyl group of the astragalus polysaccharide can be retained, so that the antibacterial property of the synthesized amino acid modified astragalus polysaccharide is significantly improved, and broad-spectrum antibacterial property can be achieved. The amino acid modified astragalus polysaccharide has excellent antibacterial activity on gram-positive bacteria and gram-negative bacteria, is a green new type of efficient antibacterial material, and is expected to become a substitute for antibiotics. The amino acid modified astragalus polysaccharide has important significance for solving the problems of increasing bacterial drug resistance and environmental accumulation caused by antibiotics, and has good application prospect.

This invention discloses a processing technology for antibody-enhancing probiotic feed, which includes raw material pretreatment, substrate preparation, sterilization, cooling, strain activation, aseptic inoculation, constant-temperature anaerobic fermentation, immune-enhancing compounding, filtration and homogenization, and aseptic filling and storage. The fermentation substrate liquid includes purified water, molasses, yeast extract, compound trace elements, and buffer salts. A compound microbial community composed of *Lactobacillus plantarum*, *Bacillus subtilis*, *Bifidobacterium*, and yeast is used for fermentation. The temperature is controlled at 35–39°C during fermentation, and intermittent stirring is employed. After fermentation, astragalus polysaccharide, echinacea extract, and trehalose are added for compounding. This invention reduces the loss of active ingredients by adding immune-enhancing components after fermentation, and improves the survival rate of probiotics and fermentation stability through intermittent stirring. The resulting liquid feed has a high live bacteria content and immune-enhancing effect.

The application relates to the field of astragalus extract technology, in particular to a preparation process of astragalus polysaccharide powder. The preparation process of the astragalus polysaccharide powder comprises the following steps: soaking astragalus medicinal materials in a soaking liquid, heating to extract astragalus polysaccharide and astragalus glycoside, separating liquid phase, concentrating the liquid phase to obtain concentrated liquid, adding a biological wrapping agent, spray drying, and obtaining astragalus polysaccharide powder; the soaking liquid comprises a co-crystal solvent and water; the biological wrapping agent can wrap the astragalus polysaccharide and the astragalus glycoside. The co-crystal solvent changes the crystal structure of the astragalus polysaccharide and the astragalus glycoside through non-covalent interaction, improves the solubility of the astragalus polysaccharide and the astragalus glycoside, and the soaking liquid heating extraction can significantly improve the extraction rate of the astragalus polysaccharide and the astragalus glycoside compared with pure water heating extraction. The biological wrapping agent is a substance that can be eaten by livestock and poultry.

The invention belongs to the technical field of microbial agents, and particularly relates to a microbial agent containing bacillus velezensis and application of the microbial agent to astragalus membranaceus. The invention discloses a microbial agent for astragalus membranaceus. The microbial agent is prepared by mixing bacillus velezensis powder, bacillus subtilis powder and bacillus pumilus powder according to the mass ratio of 1: (1-10): (1-5), the bacterium content of the bacillus velezensis powder, the bacillus subtilis powder and the bacillus pumilus powder is 0.2-0.5 billion cfu / g. The bacillus velezensis, the bacillus subtilis and the bacillus pumilus are fermented respectively, fermentation liquor is taken to be prepared into powder, and the powder is mixed according to a certain mass ratio to form the compound microbial agent, so that the compound microbial agent can improve the prevention and treatment effect on the radix astragali root knot nematode disease, is green and environment-friendly, can effectively overcome the defects of chemical agents, and has a good application prospect. Support is provided for biological prevention and control of the radix astragali root knot nematode disease, and meanwhile healthy growth of radix astragali plants can be guaranteed.

The present application belongs to the technical field of biological medicine, and particularly relates to a pharmaceutical composition for treating pulmonary fibrosis and a preparation method thereof. The composition comprises the following raw materials in parts by weight: 12-18 parts of Astragalus membranaceus, 6-12 parts of Ophiopogon japonicus, 4-10 parts of Poria cocos, 1-3 parts of Radix Glycyrrhizae, 10-16 parts of Salvia miltiorrhiza, 6-12 parts of Scutellaria baicalensis, 4-10 parts of Morus alba, 2-6 parts of Pericarpium Citri Reticulatae Viride, 1-4 parts of Sophora flavescens and 1-4 parts of Fritillaria cirrhosa. The present application is a three-phase and fixed-ratio compound of polysaccharides, phenolic acids and flavonoids. The polysaccharides are obtained by water extraction and alcohol precipitation, and are used as a mucosal retention adhesion carrier. The phenolic acids and flavonoids are extracted by low-degree ethanol refluxing, so as to ensure the structural integrity and maintain stability. The alkaloids are extracted by ethanol and then mildly salified, so as to reduce irritation and adsorption loss. The polysaccharides are then subjected to selective light fermentation to build a slightly acidic environment. In the compounding process, a buffer system is used to adjust pH, and cyclodextrin is used to stably bind the components. The three phases synergistically intervene in oxidation-inflammation-fibrosis.

The invention discloses a preparation technology of astragalus polysaccharide camouflage monosaccharide, and relates to the technical field of biological product production, the preparation technology comprises the following steps: S1, extraction, S2, purification: carrying out purification treatment on astragalus polysaccharide extracted in the step 1, S3, degradation camouflage: dissolving the astragalus polysaccharide purified in the step 2 in a solvent, carrying out degradation treatment on the astragalus polysaccharide by adopting ultrasonic waves, and carrying out purification treatment on the astragalus polysaccharide to obtain the astragalus polysaccharide camouflage monosaccharide. A specific glucan structural unit in a polysaccharide chain is degraded and disguised into a monosaccharide or oligosaccharide structure; and S4, separating to obtain a product. Astragalus polysaccharide is directionally camouflaged as a monosaccharide / oligosaccharide structure, the recognition and uptake efficiency of astragalus polysaccharide by cancer cells is remarkably enhanced, so that the targeting of inducing apoptosis of cancer cells is improved, the structure can effectively activate and train immune cells such as dendritic cells and strengthen anti-tumor immune response, and meanwhile, the product can interfere with a metabolic pathway of cancer cells and reverse the drug resistance of cancer cells, so that the anti-tumor effect is improved. Nutrition supply is blocked to inhibit tumor growth, the production process is green and controllable, and good clinical transformation and industrialization prospects are achieved.

The invention relates to the technical field of extraction and purification of natural medicines, and discloses a preparation method of high-purity astragalus polysaccharide raw material powder, which comprises the following steps: hot water extraction: extracting astragalus root powder of 80-120 meshes for 2-3 times at 80-90 DEG C for 1.5-2.0 hours each time according to a solid-to-liquid ratio of (1: 10)-(1: 30), merging filtrates, and concentrating under reduced pressure until the volume is 1 / 3-1 / 5 of the original volume; deproteinizing and decoloring: adding neutral protease to act for 1-4 hours at the temperature of 45-55 DEG C and the pH value of 6.5-7.5, and inactivating at the temperature of 90 DEG C for 10 minutes; adding 0.5%-2.0% of cross-linked polyvinylpyrrolidone, performing contact for 10-20 minutes, and performing solid-liquid separation to obtain clear liquid; and two-phase distribution and post-treatment: adding polyethylene glycol 4000 and sodium dihydrogen phosphate / disodium hydrogen phosphate into the clear liquid. The invention aims to shorten the process, improve the yield and purity and reduce protein / polyphenol and salt / polymer residues under the condition of not using ion exchange resin.

The invention discloses a preparation method of a physical adsorption and biodegradation composite mildew removing agent. The preparation method comprises the following steps: preparing modified montmorillonite: modifying sodium montmorillonite by using hexadecyl trimethyl ammonium bromide; culturing a bacillus subtilis fermentation culture: culturing bacillus subtilis CICC20683 by adopting a two-step method of seed culture and fermentation culture, and collecting thalli; culturing a lactic acid bacteria fermentation culture: culturing lactic acid bacteria CICC6078 by adopting a two-step method of seed culture and fermentation culture, and collecting thalli; and composite preparation: uniformly mixing 30-50 parts by weight of modified montmorillonite, 10-20 parts by weight of yeast cell wall polysaccharide, 20-30 parts by weight of bacillus subtilis fermentation culture, 10-20 parts by weight of lactic acid bacteria fermentation culture, 5-10 parts by weight of astragalus polysaccharide and 3-5 parts by weight of vitamin C, carrying out vacuum drying at 40 DEG C until the moisture content is lower than 8%, and crushing to 80 meshes. The preparation method is simple in process and convenient to operate, the used raw materials and equipment are common industrial raw materials and equipment, the production cost is low, and the preparation method has a good market application prospect.

The invention provides a Babylonia areolata larva disease-resistant cultivation method based on immunostimulation, and aims to solve the problems of frequent larva diseases and low survival rate in intensive cultivation. The method comprises the following steps: selecting Babylonia areolata of Thailand and Hainan populations for reciprocal cross to obtain hybrid filial generations; in the larva stage, a compound immunologic stimulant compounded by astragalus polysaccharide, peptidoglycan and beta-glucan is adopted, the concentration is accurately regulated and controlled according to the early, middle and late stages of the daughter larvae and the creeping stage, and alternate induction is conducted through water splashing and bait mixing and feeding; when the larva shell length is 30-50mm, vibrio harveyi sublethal infection is used for enhancing immune memory, and environmental parameters such as water temperature and salinity are synchronously regulated and controlled. Tests show that the method can significantly improve the growth performance, immune enzyme activity and disease resistance of larvae, the survival rate of cultivation reaches 95% or above, the natural morbidity is lower than 6%, and technical support is provided for large-scale healthy cultivation of Babylonia areolata.

The invention relates to the technical field of feed additives, and discloses a Liaoning medicinal plant extract compound feed additive, which is prepared by the following steps: uniformly mixing an acanthopanax senticosus extract, a schisandra chinensis extract, an astragalus membranaceus extract, ginseng polysaccharide and ginsenoside to obtain a compound plant extract; stearic acid and soya bean lecithin are adopted to coat the composite plant extract to form lipid nanoparticles; and mixing the lipid nanoparticles with the composite carrier, and sieving to obtain the composite feed additive. The lipid nanoparticles are loaded on the composite carrier, so that the formed composite feed additive is not easily influenced by environmental factors such as light, heat and oxygen, has relatively high activity, improves the quality of feed and the appetite of bred livestock and poultry, is relatively high in bioavailability, and improves the meat growth speed of the bred livestock and poultry.

The active oligopeptide TDGLTSLD and the astragalus polysaccharide which can improve the resistance or the immunity or the growth capacity of animals are separated from the astragalus seedlings serving as a natural source, the feed containing the oligopeptide and the polysaccharide can effectively improve the immunity of the animals, the growth capacity such as the feed conversion ratio of the animals can be improved, and the feed has a wide application prospect.

The invention discloses a tobacco leaf fermentation anti-mildew method based on an astragalus membranaceus-honeysuckle compound extract and application of the tobacco leaf fermentation anti-mildew method. The method comprises the steps that astragalus membranaceus and honeysuckle with specific indexes are screened and mixed in proportion, then ultrasonic extraction is conducted through an ethanol-water solution, and the compound extract is obtained through purification; preparing the extract into a solution, spraying the solution to pre-balanced tobacco leaves, then regulating and controlling fermentation temperature and humidity and gas concentration in stages, and monitoring microorganism and physicochemical indexes until the tobacco leaves reach the standard. According to the tobacco leaf fermentation anti-mildew method, aspergillus niger is inhibited in a targeted mode (the inhibition rate is larger than 90%), lactic acid bacteria proliferation is promoted, and the tobacco leaf mildew rate is reduced to 0%; aroma substances such as solanesol are reserved, and sensory evaluation is improved by 20%; chemical preservatives are replaced, the problems of safety dispute and flavor damage are avoided, and cigarette production requirements are met.

The invention relates to an astragalus polysaccharide continuous quantitative feeding reaction device, and belongs to the field of quantitative feeding reaction devices.The astragalus polysaccharide continuous quantitative feeding reaction device comprises a reaction kettle, the reaction kettle is communicated with a feeding shell, a material receiving hopper is arranged in the feeding shell, the lower end of the material receiving hopper is communicated with a material receiving pipe, and an auger is arranged in the material receiving pipe; a quantifying assembly is arranged at the lower end of the material receiving pipe and is used for separating the material receiving pipe from the reaction kettle. The method has the effect of conveniently controlling the dosage of the astragalus polysaccharide in the reaction process.

This application relates to a CCHG / APS composite hydrogel, its preparation method, and its application. A method for preparing the CCHG / APS composite hydrogel includes adding a chitosan solution dropwise to a carbomer solution, mixing, then adding an astragalus polysaccharide solution, adjusting the pH to 6.5-7.2, and performing cross-linking to obtain the CCHG / APS composite hydrogel. Firstly, performance characterization of the CCHG / APS hydrogel shows that it exhibits a unique loose and porous structure with good stability. Simultaneously, its rheological properties, swelling properties, and water retention capacity are all within suitable ranges, and it demonstrates excellent antibacterial properties, providing a favorable microenvironment for wound healing. In animal experiments, the CCHG / APS hydrogel exhibited a significant healing-promoting effect, and no obvious in vivo toxicity was observed throughout the experiment, confirming its good biocompatibility.

The invention provides radix astragali homogeneous polysaccharide as well as a preparation method and application thereof, and belongs to the field of separation and purification of natural products. The radix astragali homogeneous polysaccharide is composed of glucose and galactose, and the molecular weight of the radix astragali homogeneous polysaccharide is 1900-2200 Da. The preparation method comprises the following steps: performing water extraction and alcohol precipitation on astragalus membranaceus to obtain astragalus membranaceus crude polysaccharide, and performing column chromatography elution on the astragalus membranaceus crude polysaccharide to obtain the homogeneous astragalus membranaceus polysaccharide with the molecular weight of 1900-2200Da. The radix astragali homogeneous polysaccharide has excellent effects of resisting inflammation, regulating intestinal flora, regulating intestinal absorption function, scavenging free radicals, regulating immunity, improving prebiotic activity and resisting pulmonary fibrosis.

The application provides a medicine composition for treating hepatobiliary diseases and a preparation method thereof, and the active ingredients are composed of a compound shown in formula (I) and Astragalus membranaceus and Saussurea involucrata extract, the weight ratio of the compound shown in formula (I) to the Astragalus membranaceus and Saussurea involucrata extract is 1: (1.5-2.0) by weight; compared with the prior art, the medicine composition of the application has a synergistic effect on hepatobiliary diseases, especially gallstones, and the effect is remarkable.

The invention provides a preparation method of gecko health-care wine, which comprises the following steps: disinfecting cleaned gecko with 50-degree white spirit, and carrying out wall-breaking crushing together with auxiliary medicinal materials, the auxiliary medicinal materials comprise radix ginseng rubra, radix rehmanniae preparata, fructus lycii, rhizoma dioscoreae, radix achyranthis bidentatae, rhizoma cibotii, fructus corni, deer glue, radix astragali, semen cuscutae, tortoise-shell glue, rhizoma gastrodiae, cortex eucommiae, fructus alpiniae oxyphyllae, herba epimedii, spica prunellae, radix angelicae sinensis, cortex cinnamomi, mulberry, herba cistanche, radix polygoni multiflori, fructus rubi and herba cynomorii Sub-packaging the crushed mixture into breathable medicine bags; baijiu with the alcoholic strength of 50 degrees or above is injected into a ceramic wine jar, and the medicine bag is added; soaking for 10 days, and gently turning the medicine bag once every day during soaking; and filtering and sub-packaging to obtain finished wine. 24 medicinal materials are scientifically matched according to monarch, minister, assistant and guide, the blood oxygen saturation degree is improved, the problems of fatigue, sleep quality, respiratory function and kidney qi deficiency are solved in a multi-target mode, the mulberry ellagic acid attenuation technology is adopted, the content of free anthraquinone in polygonum multiflorum is reduced, the fishy smell of mulberry and fructus lycii is neutralized, and palatability is improved.

The present application relates to the technical field of polysaccharide modification, and specifically discloses a glutamic acid modified astragalus polysaccharide, a preparation method thereof and an antioxidant application thereof. The preparation method comprises the following steps: adding a glutamic acid aqueous solution and epichlorohydrin into an alkaline solution, uniformly mixing, reacting at 50-60 DEG C for 2-3 hours to obtain an intermediate product; uniformly mixing astragalus polysaccharide, an alkaline solution and an alcohol solution, adding the intermediate product, reacting at 50-60 DEG C for 3-5 hours to obtain the glutamic acid modified astragalus polysaccharide. The present application uses naturally degradable astragalus polysaccharide as a substrate, and modifies the astragalus polysaccharide by using glutamic acid through a reasonable and feasible green process, so that the antioxidant property of the astragalus polysaccharide is significantly improved, and the water-insoluble content is obviously reduced, thereby effectively increasing the addition amount of the astragalus polysaccharide in cosmetics, significantly improving the practicability, and having a wide application prospect in antioxidant and anti-aging cosmetics.

This application discloses a method for preparing a novel topical Tiger Yellow Healing Traditional Chinese Medicine (TCM) preparation for treating wounds, comprising the following steps: S1, preparation of medicinal materials: Seven medicinal materials powders are obtained by grinding or pulverizing Bauhinia bark, Astragalus membranaceus, Angelica pubescens, Saxifraga stolonifera, Paeonia lactiflora, Acorus tatarinowii, and Angelica dahurica; S2, preparation of homologous carbon quantum dots; S3, preparation of a TCM compound; S4, mixing the homologous carbon quantum dots obtained in step S2 with the TCM compound obtained in step S3, dialysis the mixture with distilled water to remove unloaded small molecules of the TCM compound, and then drying to obtain the Tiger Yellow Healing TCM preparation. This application also provides an application of this novel topical Tiger Yellow Healing TCM preparation for treating wounds. This application is the first to propose a method for preparing a TCM compound loaded with homologous carbon quantum dots, increasing the efficacy of the TCM compound itself. It can be used to treat various acute wounds and chronic, difficult-to-heal wounds, promote rapid wound healing, and has good antibacterial, antioxidant, and wound angiogenesis effects.

The invention belongs to the technical field of probiotic preparations, and particularly relates to lactobacillus paracasei and application of the lactobacillus paracasei in a probiotic delivery system for reducing blood pressure. The lactobacillus paracasei provided by the invention is screened from Tibetan traditional fermented dairy products, and is proved to have good hypertension reducing capacity. According to a probiotic delivery system constructed by using the strain, the astragalus polysaccharide is subjected to oxidation modification; the oxidized astragalus polysaccharide and carboxymethyl chitosan with amino groups can quickly form gel through a Schiff base reaction, and a dense microsphere structure of a cross gel network is formed in a sodium alginate-metal ion hydrogel system, so that the embedding of lactobacillus paracasei is realized, and the delivery efficiency of probiotics is improved; meanwhile, the functional characteristics of the probiotics in the aspect of reducing hypertension can be effectively enhanced by virtue of the prebiotic characteristics of the astragalus polysaccharide. Therefore, the invention can provide a new thought and method for microbial treatment of hypertension, and provides a theoretical basis for development of drugs or health care products for reducing hypertension.

The invention discloses a tablet suitable for rheumatoid arthritis and a preparation method thereof. The tablet comprises a formula I and a formula II, wherein the formula I comprises codonopsis pilosula, radix angelicae pubescentis, loranthus parasiticus, gentiana macrophylla, asarum, angelica sinensis, radix paeoniae alba, ligusticum wallichii, radix rehmanniae recen, eucommia ulmoides, achyranthes bidentata, poria cocos, bighead atractylodes rhizome, cinnamon and liquorice; a formula II: astragalus membranaceus, radix rehmanniae preparata, medlar, pulp of dogwood fruit, semen brassicae, rhizoma arisaematis, ground beetle, dendrobe, rhizoma anemarrhenae and divaricate saposhnikovia root; a formula III: peach kernel, safflower, rhizoma cyperi, earthworm, trogopterus dung, oriental stephania root, notopterygium root, pinellia ternate, fructus aurantii, corydalis tuber, curcuma zedoary, leech, herba lycopi and centipede; and a formula IV is prepared from honeysuckle flower, radix scrophulariae, cortex acanthopanacis, turmeric, rhizoma cibotii, scorpio and stiff By analyzing the pharmacological characteristics of all the traditional Chinese medicine raw materials, integrating the disease characteristics of rheumatoid arthritis, performing scientific compatibility and fully exerting the pharmacological characteristics of all the components, the pharmacological activity of all the components for dispelling wind and eliminating dampness, activating meridians to stop pain and clearing heat and dispelling cold is reserved, and the traditional Chinese medicine composition can be directly taken orally and is convenient to use.

The invention discloses a probiotic fermentation method for improving total saponins of astragalus membranaceus based on response surface optimization, which comprises the following steps: inoculating a fermentation seed solution into a fermentation substrate containing astragalus membranaceus, and carrying out shake culture for 48 hours under the conditions of 40-45 DEG C and 150-200r / min; the inoculation amount is 1-5%; the fermentation seed liquid is obtained by culturing lactobacillus delbrueckii subsp. Bulgaricus CICC 20247; the fermentation substrate containing astragalus membranaceus comprises astragalus membranaceus powder, skim milk powder, white granulated sugar, yeast extract and sterile water. After the lactobacillus delbrueckii subsp. Bulgaricus CICC20247 liquid is used for fermenting the astragalus membranaceus, the content of total saponins in the astragalus membranaceus can be greatly increased, and the medicine effect of the astragalus membranaceus can be improved.

The utility model discloses a seed screening device for astragalus mongholicus planting, and relates to the technical field of agricultural planting, the seed screening device for astragalus mongholicus planting comprises a screening box, the upper end of the screening box is provided with a feed port, a second filter plate is arranged in the screening box, the lower end of the screening box is provided with a discharge port, and the discharge port is provided with a first filter plate and a second filter plate. A second collecting box is arranged at the lower end of the discharging port, a protruding block is arranged at the lower end of the screening box, a vibration motor box is arranged on one side of the protruding block, four sets of connecting blocks are arranged on the outer side of the screening box, the connecting blocks are symmetrically arranged on the two sides of the screening box in pairs, and bolts are arranged on the connecting blocks. And the connecting blocks are connected with the screening box through bolts, first springs are arranged at the lower ends of the connecting blocks, first damping rods are arranged in the first springs, and the problem that the screening efficiency is low is solved through the scheme.

The present invention relates to a phytological composition as a hemostatic agent, for example for use in the treatment of wounds and / or bleeding lesions of the skin and / or mucous membranes. The phytological composition consists of a polysaccharide of Tremella fuciformis, an extract of leaves of Vitis vinifera, an extract of leaves of Astragalus membranaceus, an extract of Medicago sativa, an extract of Fucus vesiculosus, a powder of Spirulia platensis, an extract of root of Beta vulgaris and an extract of Polygonum cuspidatum. The present invention also relates to pharmaceutical formulations comprising said phytological composition together with suitable pharmaceutically acceptable excipients.

The present application relates to the technical field of food 3D printing, and discloses a method for determining 3D printing parameters of non-starch polysaccharide in starch-based food, astragalus polysaccharide composite gel and a preparation method thereof, and a method for determining optimal printing parameters, which comprises preparing gel material for 3D printing, and the preparation raw material of the gel material comprises non-starch polysaccharide and starch, the gel material is sent into a 3D printer for printing, and the influence of different printing speeds, filling rates and nozzle diameters on the quality of the formed sample is studied through single-factor test, the quality of the formed sample is evaluated based on comprehensive printing accuracy and quality index, and the optimal values of the printing speed, the filling rate and the nozzle diameter are determined, the present application provides a method for quickly determining 3D printing parameters of non-starch polysaccharide in starch-based food, and uses astragalus polysaccharide and wheat starch as raw materials, so that the strength of the gel material can be effectively improved, the printing accuracy of the formed product can be improved, and problems such as difficulty in internal refinement of the gel material are effectively solved, and the preparation method is simple, low in cost and short in time consumption.

The invention relates to the technical field of gel, in particular to wound nursing gel with double-effect repair functions of healing promotion and scar inhibition and a preparation method of the wound nursing gel. According to the preparation method disclosed by the invention, through the mutual cooperation of the modified astragalus polysaccharide, namely the precise navigation of a conjugate formed by collagen targeting peptide-astragalus polysaccharide, the deep anti-inflammatory regulation of dipotassium glycyrrhizinate and the high-quality template guidance of recombinant humanized III-type collagen, the traditional passive repair is upgraded to active guided repair; the contradiction between the healing speed and the healing quality is coordinated from the source. According to the invention, the wound closure can be obviously accelerated (the early healing rate is improved by about 3 times), and scars can be inhibited fundamentally. Experiments prove that the proportion of type III collagen of new dermis can be increased to be close to the normal skin level (about 42%), and collagen fibers are highly ordered in arrangement (the orientation degree reaches 0.91), so that physiological regeneration instead of pathological scar repair in a real sense is realized.

The application provides a preparation method of a test sample in a content determination method of Astragalus membranaceus, which comprises the following steps: a, taking Astragalus membranaceus medicinal material powder, and sieving; b, placing the powder into a stoppered conical flask, adding 20-100 ml of 1-6 % ammonia solution-methanol solution (4 ml of ammonia solution is taken, 50 % methanol is added to 100 ml, and shaking is performed), weighing, ultrasonic extraction (250 W, 40 kHz) is performed for 10-90 min, cooling, weighing again, supplementing the lost weight with 1-6 % ammonia solution-methanol solution, shaking, filtering, and taking the filtrate, so that the test sample is obtained. The application further provides a content determination method of calycosin-7-glucoside in Astragalus membranaceus. The optimized method is stable and feasible, simple in operation, high in extraction efficiency, short in analysis time, low in detection cost, and accurate in determination, and can provide a scientific basis for improving the content determination method of calycosin-7-glucoside in Astragalus membranaceus in Chinese Pharmacopoeia.

The invention discloses Yao-strengthening ointment for improving immune disorder of an HIV infected person. The Yao-strengthening ointment is mainly prepared from the following raw materials: astragalus membranaceus, poria cocos, rhizoma cimicifugae, radix achyranthis bidentatae, roasted ephedra, prepared radix aconiti carmichaeli, asarum, roasted liquorice, philippine flemingia root, giantleaf ardisia rhizome, caulis sinomenii, tripterygium wilfordii and gynostemma pentaphylla. The preparation method of the Zhuang Yao ointment comprises the steps of medicinal material treatment, medicinal material extraction and ointment preparation. The whole formula is mainly used for strengthening the body resistance (tonifying qi and warming yang) and eliminating evil (dehumidifying, activating blood and detoxifying), through the compatibility of monarch, minister, assistant and guide, the traditional Chinese medicine aims at core qi deficiency and yang deficiency of immune disorder of HIV infected people and also eliminates pathological products such as dampness, stasis and heat toxin, meanwhile, honey-fried licorice root is used for regulating the medicine property, CD4 cells of the HIV infected people can be improved, immune disorder can be improved to a certain extent, and immune reconstitution is promoted.