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Liquid ventilator and method to induce tidal liquid ventilation and/or hyporthermia

A ventilator and liquid technology, applied in the field of artificial ventilators, can solve the problems of TLV technology deployment and use restrictions

Pending Publication Date: 2021-05-07
SCOPRA SCI & GENIE SEC +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Unfortunately, the deployment and use of TLV technology is limited in clinical settings

Method used

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  • Liquid ventilator and method to induce tidal liquid ventilation and/or hyporthermia
  • Liquid ventilator and method to induce tidal liquid ventilation and/or hyporthermia
  • Liquid ventilator and method to induce tidal liquid ventilation and/or hyporthermia

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Embodiment Construction

[0084] Novel ventilators, devices and methods are described below. While the invention has been described in terms of particular illustrative embodiments, it should be understood that the embodiments described herein are by way of example only and that the scope of the invention is not intended to be limited thereby.

[0085] Over the past few decades, the development of protective mechanical ventilation for critically ill patients in the intensive care unit has taken an important step forward. One of the next medical breakthroughs is total liquid ventilation (TLV) using the lungs with residual volumes of perfluorocarbons, on top of which the tidal volume of liquid is increased or decreased in each breathing cycle. As shown in animal models of respiratory diseases, TLVs are able to ensure normal gas exchange and provide lung function due to the high solubility of PFCs for gases. When delivered with a temperature-controlled PFC, it was also able to use the lungs as a heat exch...

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Abstract

Liquid ventilator and methods integrating the concept of total liquid ventilation (TLV) using liquid volumes below functional residual capacity (FRC) of mammal's lungs are disclosed. Beyond the automatization of the whole process, the technology has been up-scaled to confirm that TLV at residual volumes below FRC can provide a safe procedure while enabling the full potential of TLV in a mammal such as humans or adult-sized animals. Such tidal liquid ventilation strongly differs from the previously known TLV approach, opening promising perspectives for a safer clinical translation. Also disclosed are apparatus and method for safe and fast induction of hypothermia during liquid ventilation of a mammal.

Description

[0001] Claims of priority under 35 U.S.C S.119(e) and 37 C.F.R.S.1.78 [0002] This non-provisional patent application claims priority based on an earlier patent application: No. EP18020155.0 in English titled "Method and device for determining and preventing an expiratory collapse (method and device for determining and preventing expiratory collapse)", and EP18020156.8 entitled "Method and device for determining and preventing a low temperature (method and device for determining and preventing low temperatures)", both filed with the European Patent Office on April 17, 2018, these The content of the application is incorporated herein by reference in its entirety. technical field [0003] The invention relates to the field of artificial ventilators, in particular to airway pressure and lung temperature. Background technique [0004] The artificial mechanical ventilation concept includes mechanical ventilators, high-frequency ventilators, and can be extended to other devices ...

Claims

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Application Information

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IPC IPC(8): A61M16/00A61M16/10A61M16/14A61M16/20
CPCA61M16/0054A61M2205/3368A61M16/0009A61M2205/3344A61M16/0051A61M16/024A61M2230/202A61M2230/205A61M2230/208A61M16/0463A61M16/201A61M2205/502A61M2205/583A61M2205/52A61M2205/3561A61M2209/084A61M2202/0476A61M2016/0027A61M16/0072A61M16/0833A61M16/0891A61M16/1045A61M2210/1032A61M16/202A61M16/0003A61M16/1075A61M16/1005A61M19/00A61F7/12A61F7/0085A61M2016/0036A61M2230/46A61M2205/3606A61M2205/362A61F2007/0064A61F2007/0086A61F2007/126A61M16/208A61M2202/02A61M2205/366
Inventor 菲利普·米绍雷诺·蒂西耶马蒂亚斯·科尔豪尔朱利安·穆索马蒂厄·纳多乔纳唐·旺达姆
Owner SCOPRA SCI & GENIE SEC
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