Anti-wrinkle skin-care cosmetic composition containing polypeptide and preparation method of anti-wrinkle skin-care cosmetic composition

A technology of cosmetic composition and skin care cosmetics, which is applied in the direction of cosmetic preparations, cosmetics, medical preparations containing active ingredients, etc., which can solve the problems of non-permanent, insignificant anti-wrinkle effect, and not very prominent anti-wrinkle effect, so as to promote Metabolism, enhanced skin immunity, anti-wrinkle effect outstanding effect

Inactive Publication Date: 2021-08-17
HANGZHOU GOTOP BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In daily life, people usually use anti-aging cosmetics to eliminate wrinkles. The common anti-aging cosmetics are vitamins and enzymes, such as superoxide dismutase (SOD). Similar products on the market include Dabao SOD Honey, Ica Luwei CSOD honey, etc., all use superoxide dismutase (SOD). However, the anti-wrinkle effect of superoxide dismutase (SOD) is not very prominent, and the anti-wrinkle effect always has the problem of not being obvious and not lasting.

Method used

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  • Anti-wrinkle skin-care cosmetic composition containing polypeptide and preparation method of anti-wrinkle skin-care cosmetic composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] The preparation method of ajirelin is as follows:

[0053]S1. Weigh 100g of Rink Amide-AM Resin resin with a substitution degree of 0.70mmol / g into the reaction column, add an appropriate amount of DCM to swell for 15min, drain it, wash it with DMF for 3 times, then drain it, and add an appropriate amount of decapping solution to react for 5min Finally, drain the capping liquid, wash once with an appropriate amount of DMF, then add an appropriate amount of capping liquid to react for 10 minutes, drain the capping liquid, wash 6 times with DMF, and dry it. Wherein, the capping liquid is composed of DBLK and DMF according to the volume ratio of 1:4 configuration;

[0054] S2. Weigh 148.02g of Fmoc-Arg(pbf)-Arg(pbf)-OH and 44.95g of TBTU, completely dissolve in an appropriate amount of DMF, slowly add 46.28ml of DIEA under ice-bath conditions, and stir slowly, and the uniformly stirred Fmoc- The mixed solution of Arg(pbf)-Arg(pbf)-OH / TBTU / DIEA was slowly added to the reac...

Embodiment 2

[0060] The preparation method of cucumber extract is as follows:

[0061] S1. Weighing raw materials in percentage by weight: cucumber extract 8%, glycerin 6%, tocopherol 3%, myristyl alcohol 2%, pentylene glycol 4%, deionized water 77%;

[0062] S2. Add glycerin, myristyl alcohol, and pentylene glycol to water, heat to 75° C. to melt, and stir evenly while heating;

[0063] S3. Cool the dissolved glycerin, myristyl alcohol, and pentylene glycol mixture to 42°C, slowly add cucumber extract and tocopherol during stirring, stir and mix evenly and slowly cool to 28°C, then seal to obtain cucumber extract things.

Embodiment 3

[0065] The preparation method of honeysuckle extract is as follows:

[0066] S1. Weigh the raw materials in percentage by weight: 6% of honeysuckle extract, 7% of glycerin, 2% of butylated hydroxytoluene, 1% of myristyl alcohol, 2% of pentylene glycol, and 82% of deionized water;

[0067] S2. Add glycerin, myristyl alcohol, and pentylene glycol to water, heat to 75° C. to melt, and stir evenly while heating;

[0068] S3. Cool the dissolved glycerin, myristyl alcohol, and pentylene glycol mixture to 40°C, slowly add honeysuckle extract and butylated hydroxytoluene during the stirring process, stir and mix evenly, slowly cool to 28°C, and then seal to obtain honeysuckle Extract.

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Abstract

The invention discloses an anti-wrinkle skin-care cosmetic composition containing polypeptide and a preparation method of the anti-wrinkle skin-care cosmetic composition. Each gram of cosmetic composition comprises the following components: 1-8% of argireline; 15-35% of a cucumber extract; 15-35% of a honeysuckle flower extract; and 15-35% of a sophora flower extract. According to the cosmetic composition, polypeptide and various components can be combined to achieve a mutual synergistic effect, by trying on 40 volunteers, the cosmetic composition can restore the skin color to be smooth and elastic, has the effects of preserving moisture and locking water, can adjust the water-oil balance of the skin and has the effects of resisting wrinkles and protecting the skin, the anti-wrinkle effect is prominent, and the cosmetic composition has a good application prospect. The anti-wrinkle mask has an obvious and lasting anti-wrinkle effect and is suitable for people with various skin types.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a polypeptide-containing anti-wrinkle skin care cosmetic composition and a preparation method thereof. Background technique [0002] The appearance of wrinkles is a significant manifestation of human aging. In addition to natural physiological factors, human skin aging is also related to factors such as long-term sleep quality, ultraviolet radiation, working environment, living habits, nutritional status, and skin maintenance. Wrinkles are mainly caused by free skin. Produced under the action of free radicals, due to the influence of the external environment and internal physiological conditions, when the human body produces free radicals, free radicals will destroy the structure of normal cell tissues, resulting in damage to skin collagen and active substances, and gradually form wrinkles. [0003] In daily life, people usually use anti-aging cosmetics to eliminate wrinkles. T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/64A61Q19/08A61Q19/00
CPCA61K8/9789A61K8/64A61Q19/08A61Q19/00A61K2800/592
Inventor 沈永刚肖攀谢振亮付坤沈永良程益明胡桂香
Owner HANGZHOU GOTOP BIOTECH
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