Multi-parameter detection array electrochemical sensor for continuous blood gas detection

A detection array, multi-parameter technology, applied in the field of blood gas detection sensors, can solve the problems of difficult continuous monitoring, no way to meet the fast, accurate and continuous detection of targets, etc., and achieve the effect of high measurement accuracy

Pending Publication Date: 2021-09-07
TIANJIN UNIV
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Problems solved by technology

However, the current blood gas detection mainly focuses on the in vitro detection of arterial blood or venous blood samples. There are generally differences between the samples tested in vitro and the...

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  • Multi-parameter detection array electrochemical sensor for continuous blood gas detection
  • Multi-parameter detection array electrochemical sensor for continuous blood gas detection

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Embodiment 1

[0028] Such as figure 1 , figure 2 As shown, a multi-parameter detection array electrochemical sensor for continuous blood gas detection consists of an electrode layer 7, an insulating layer 8, a hydrophilic film layer 9 and a shell protection layer 10 from the glass substrate 6 up to the top, and the electrode layer 7 Including three working electrodes and a common reference electrode 4, the three working electrodes and a common reference electrode are integrated on the surface of the same glass substrate through electrode leads 1 to realize array miniaturization, wherein,

[0029] The first working electrode 2 is also referred to as the pH working electrode, and is prepared by the following method: a gold layer is prepared on the glass surface; then the surface is modified by 3,4-ethylenedioxythiophene monomer polymer ( PEDOT) and polystyrene sulfonate (PSS) mixed solution (mixed solution purchased from Sigma-Aldrich company) to obtain solid electrolyte; in the dry solid e...

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Abstract

The invention provides a multi-parameter detection array electrochemical sensor for continuous blood gas detection. The multi-parameter detection array electrochemical sensor sequentially comprises an electrode layer (7), an insulating layer (8), a hydrophilic film layer (9) and a shell protection layer (10) from a glass substrate (6) to the top, wherein the electrode layer (7) comprises three working electrodes and a common reference electrode (4), and the three working electrodes and the common reference electrode are integrated on the surface of the same glass substrate to realize array miniaturization. The sensor realizes synchronous and continuous detection of different substances in blood through cooperative work of a plurality of specific working electrodes.

Description

technical field [0001] The invention relates to a blood gas detection sensor, in particular to a multi-parameter detection array electrochemical sensor for continuous blood gas detection. Background technique [0002] Blood gas detection is to use a blood gas analyzer to analyze blood gas, by measuring the H of human blood + Concentration and gas dissolved in the blood (mainly refers to CO 2 , O 2 ), a means to understand the human respiratory function and acid-base balance, which can directly reflect the lung ventilation function and its acid-base balance. [0003] Arterial blood gas analysis and central venous blood gas analysis are two common clinical applications at present. Arterial blood gas analysis can accurately reflect the status of oxygenation, ventilation status and acid-base balance. However, arterial blood sampling will be accompanied by many complications, such as local arterial spasm, wound infection, nerve damage, arterial thrombosis, etc.; and this inva...

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Application Information

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IPC IPC(8): G01N27/327
CPCG01N27/327G01N27/3275
Inventor 蒲治华李成成于海霞
Owner TIANJIN UNIV
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