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Semen ziziphi spinosae pressure-resistant and sleep-aiding compound and preparation method thereof

A kind of jujube seed and sleep aid technology, which is applied in food science, drug combination, medical formula, etc., can solve the problems of reducing the patient's response ability, drug withdrawal rebound, and long-term use dependence.

Inactive Publication Date: 2021-09-10
河北中科同创科技发展有限公司 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the continuous development of society, people's personal abilities need to be continuously improved, and people are facing more and more pressure. People who suffer from high pressure for a long time can easily lead to insomnia, and long-term insomnia will cause immunity decline and mental breakdown , headache, inability to concentrate, dark circles, bags under the eyes, dry skin, dark spots, acne, forgetfulness, irritability, anxiety and other symptoms; most of the existing products for the treatment of insomnia on the market are western medicines, and western medicines have no effect on insomnia. There are two types of commonly used western medicines for the treatment of the disease. The first type is benzodiazepine sedative and hypnotics. Commonly used drugs include alprazolam, estazolam, clonazepam, etc. The disadvantage is that there is dependence and withdrawal rebound phenomenon
The second category is non-benzodiazepine sedative and hypnotics, mainly including zopiclone, eszopiclone, zaleplon, etc. Long-term use will reduce the patient's responsiveness to a certain extent
Therefore, there is a need for a product that has a significant sleep-promoting effect, has the effect of relieving pressure, can make people feel relaxed, can have a calming effect, can also enhance the immunity of the human body, and has no toxic and side effects; while avoiding the use of existing western medicines Cause long-term use dependence and drug withdrawal rebound phenomenon

Method used

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  • Semen ziziphi spinosae pressure-resistant and sleep-aiding compound and preparation method thereof
  • Semen ziziphi spinosae pressure-resistant and sleep-aiding compound and preparation method thereof
  • Semen ziziphi spinosae pressure-resistant and sleep-aiding compound and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A preparation method for anti-stress and sleep-improving compound of jujube seed, comprising the following steps:

[0035] (1) Wash 30g jujube seed, 25g white lentils, 20g mulberry leaves, 20g poria cocos, 20g lily, 20g dandelion, 14g double rose, and 20g wild ginseng;

[0036] (2) Mix the cleaned jujube kernels, white lentils, mulberry leaves, poria cocos, lily, dandelion, double-petal roses, and wild ginseng into a water extraction pot and add pure water for 30 minutes at a mass ratio of 1:9. ;

[0037] (3) Put the cooked feed liquid in step (2) into a fermenter, and inoculate 6g of probiotics for fermentation. The probiotics are a mixture of Clostridium clostridium and Lactobacillus plantarum, and among the probiotics, Clostridium clostridium The mass ratio between bacteria and Lactobacillus plantarum is 0.8:1, and the viable counts of Clostridium clostridium and Lactobacillus plantarum are respectively 1*10 7 CFU / g, seal the fermenter so that the fermentation temp...

Embodiment 2

[0042] A preparation method for anti-stress and sleep-improving compound of jujube seed, comprising the following steps:

[0043] (1) Wash 20g jujube seed, 30g white hyacinth bean, 10g mulberry leaf, 30g poria cocos, 10g lily, 30g dandelion, 12g double rose, and 30g wild ginseng;

[0044] (2) Mix the cleaned wild jujube kernels, white lentils, mulberry leaves, poria cocos, lilies, dandelions, double-petal roses, and wild ginseng into a water extraction pot and add pure water at a ratio of 1:8 to extract for 40 minutes;

[0045] (3) Put the cooked feed liquid in step (2) into a fermenter, and inoculate 10g of probiotics for fermentation, the probiotics are a mixture of Clostridium clostridium and Lactobacillus plantarum, and among the probiotics, Clostridium clostridium The mass ratio between bacteria and Lactobacillus plantarum is 0.8:1, and the viable counts of Clostridium clostridium and Lactobacillus plantarum are respectively 1*10 7 CFU / g, seal the fermenter so that the f...

Embodiment 3

[0049] A preparation method for anti-stress and sleep-improving compound of jujube seed, comprising the following steps:

[0050] (1) Wash 40g jujube seed, 20g white hyacinth bean, 30g mulberry leaf, 10g poria cocos, 30g lily, 10g dandelion, 16g double rose, and 10g wild ginseng;

[0051] (2) Mix the cleaned jujube kernels, white lentils, mulberry leaves, poria cocos, lily, dandelion, double-petal roses, and wild ginseng into a water extraction pot and add pure water in a ratio of 1:9 to extract for 40 minutes;

[0052] (3) Put the cooked feed liquid in step (2) into a fermenter, and inoculate 3g of probiotics for fermentation, the probiotics are a mixture of Clostridium clostridium and Lactobacillus plantarum, and among the probiotics, Clostridium clostridium The mass ratio between bacteria and Lactobacillus plantarum is 0.9:1, and the viable counts of Clostridium clostridium and Lactobacillus plantarum are respectively 1.5*10 7 CFU / g, seal the fermenter so that the fermenta...

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Abstract

The invention is applicable to the technical field of functional foods, and provides a semen ziziphi spinosae pressure-resistant and sleep-aiding compound and a preparation method thereof. The semen ziziphi spinosae pressure-resistant and sleep-aiding compound comprises the following components of semen ziziphi spinosae, semen lablab album, folium mori, poria cocos, bulbus lilii, herba taraxaci, flos rosae rugosae and mountain ginseng. A formula in the embodiment of the invention is scientific and reasonable, and the compound prepared by the embodiment of the invention has a remarkable sleep-aiding effect, has a pressure-relieving effect, can enable people to feel relaxed, also has a tranquilizing effect, can also enhance the immunity of the human body, and is free of toxic and side effects; and the problem that the response ability of a patient may be reduced due to the dependence and the drug withdrawal rebound phenomenon caused by long-term use of existing western medicine is avoided.

Description

technical field [0001] The invention belongs to the technical field of functional foods, and in particular relates to an anti-stress and sleep-improving compound of jujube seed and a preparation method thereof. Background technique [0002] With the continuous development of society, people's personal abilities need to be continuously improved, and people are facing more and more pressure. People who suffer from high pressure for a long time can easily lead to insomnia, and long-term insomnia will cause immunity decline and mental breakdown , headache, inability to concentrate, dark circles, bags under the eyes, dry skin, dark spots, acne, forgetfulness, irritability, anxiety and other symptoms; most of the existing products for the treatment of insomnia on the market are western medicines, and western medicines have no effect on insomnia. There are two types of commonly used western medicines for the treatment of the disease. The first type is benzodiazepine sedative and hy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8967A61P25/00A61P25/20A61P37/04A23L33/10
CPCA61K36/725A61K36/48A61K36/605A61K36/076A61K36/8967A61K36/288A61K36/738A61K36/258A61P25/00A61P25/20A61P37/04A23L33/10A61K2236/19A61K2236/331A23V2002/00A61K2300/00A23V2200/322
Inventor 康跻耀王洋洋张玲云刘佳丽彭云花王军磊
Owner 河北中科同创科技发展有限公司
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