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Large dose disposable inhaler and method of simple filling

An inhaler, inhalation channel technology, applied in the field of novel disposable lung or nasal inhalers, which can solve the problems of lost production, cost, and complexity of medicinal powder

Active Publication Date: 2021-09-28
HOVIONE SCIENTIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, the construction of the disposable inhaler described in PT103481 and PT108426 requires that the industrial scale filling of the disposable inhaler be carried out in the disassembled configuration of the inhaler, since the cartridge is required to be in the disassembled state with respect to the body of the disposable inhaler. The powder dose is filled into the cartridge and the cartridge is located in a specially designed, industrial-scale capable robotic device that provides sealing of the cartridge compartment during filling and subsequent direct removal of the filled cartridge. position and mechanically assembled to the body where the hatches are isolated and sealed, and it has been found that such filling requirements result in additional powder loss and production complexity and cost

Method used

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  • Large dose disposable inhaler and method of simple filling
  • Large dose disposable inhaler and method of simple filling
  • Large dose disposable inhaler and method of simple filling

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Embodiment Construction

[0052] Hereinafter, the present invention will be described based on the drawings. It is to be understood that the embodiments and aspects described herein are exemplary only and do not limit the scope of the claims in any way. The invention is defined by the claims and their equivalents. It is to be understood that features of one aspect or embodiment of the invention may be combined with features of one or more different aspects and / or embodiments of the invention.

[0053] Referring to the accompanying drawings (the drawings are numbered according to the word "figure"), like numerals denote similar parts, and various embodiments or aspects are represented by a series of numerals, wherein the number in the hundreds place is the number of embodiments or aspects (1xx to 7xx), and equivalent features in various embodiments or aspects have the same number xx.

[0054] refer to Figure 2a and 2b , shows an inhaler body 201 comprising a mouthpiece or nosepiece 202 which engages...

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Abstract

A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body (201) and a cartridge (203) with a plurality of powder compartments (205) each including one dose of a drug. The body (201) has an opening (204) shaped for receiving the cartridge (203) and the plastic body recess (215) and the detent (218) to allow a controlled advancement and turning movement of the cartridge (203) relative to the body (201) for sequentially delivering each of the plurality of unit doses filled into the cartridge compartments (205). The inhaler construction is suitable for filling the plurality of unit doses into the compartments (205) with the cartridge (203) assembled into the body (201). The invention affords a large dose inhaler of single-use and low cost that improves industrial filling and manufacturing cost for the delivery of high dosages of inhaled medicines.

Description

technical field [0001] The present invention relates to novel disposable pulmonary or nasal inhalers of simple construction and operation, which are convenient and low cost for industrial filling, suitable for the delivery of very large doses of pharmaceutical compounds. Background technique [0002] Inhalers for the delivery of pharmaceutical compounds have become common, especially powder-based inhalers that utilize the patient's spontaneous inhalation effort as the energy source for drug delivery, mainly for the treatment of chronic respiratory diseases such as asthma or Treatment of chronic obstructive pulmonary disease, but also for the treatment of acute symptoms, such as delivery of anti-infectious drugs, rescue drugs for emergency respiratory conditions, and local delivery of antibiotics and anti-cancer drugs to diseased lungs. Additionally, the rapid drug onset and lower total doses of pulmonary drug delivery via powder inhalers have been exploited for systemic drug...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M15/00
CPCA61M15/0048A61M15/005A61M2202/064A61M2206/16A61M2209/045A61M15/0023A61M15/0021A61M15/0086A61M15/08
Inventor J·文图拉P·维拉什A·卡瓦略D·卡拉梅洛S·若苏埃
Owner HOVIONE SCIENTIA