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A storage and encryption method for DNA hybridization information based on probe blocking and unblocking

An encryption method and information storage technology, which is applied in the field of DNA hybridization information storage encryption based on probe sealing and unblocking, can solve the problems of low information security and DNA hybridization storage technology has not yet realized the encryption function, and achieve the goal of improving security Effect

Active Publication Date: 2022-06-17
HUNAN UNIV OF SCI & TECH
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0003] In order to solve the defects and deficiencies in the current technology, the purpose of the present invention is to provide a DNA hybridization information storage encryption method based on probe blocking and unblocking, to solve the problem that the existing DNA hybridization storage technology has not yet realized the encryption function and the information security is low. technical issues

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  • A storage and encryption method for DNA hybridization information based on probe blocking and unblocking
  • A storage and encryption method for DNA hybridization information based on probe blocking and unblocking
  • A storage and encryption method for DNA hybridization information based on probe blocking and unblocking

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Embodiment 1

[0044] Specifically, the embodiment of the present invention provides a DNA hybridization information storage and encryption method based on probe sealing and unsealing. The following will take the writing target information "encryption" (two Chinese characters) as an example to describe the DNA information storage encryption method of the present invention. Further detailed instructions include the following steps:

[0045] like figure 2 As shown, the present embodiment DNA information storage parallel addressing and writing method includes:

[0046] 1) The target information, namely "encryption" two Chinese characters are converted into binary codes, 10111100110100111100001111011100 and divided into 8 fields, each field corresponds to a data unit, including 4 binary digits;

[0047] 2) Map the 1 / 0 value on the 4 binary digits of each of the above fields to the presence / absence combination of the 4 DNA coding strands B1, B2, B3, and B4; for example, the first digit (corresp...

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Abstract

The invention discloses a method for storing and encrypting DNA hybridization information based on probe sealing and unblocking, and belongs to the technical field of DNA storage. The method for storing and encrypting DNA hybridization information based on probe blocking and unblocking includes a set of DNA oligonucleotide probe combinations with fluorescent groups, quenching groups and restriction endonuclease recognition sites and a A set of restriction endonuclease combinations; wherein, a specific restriction endonuclease can excise the quenching group of a specific probe, thereby activating the probe; during the DNA hybridization process of DNA hybridization storage information reading, if Direct use of probes that have not been properly activated, due to the existence of quenching groups, cannot obtain effective fluorescent detection signals after hybridization, nor can the stored information be read. The invention realizes the hard encryption of the DNA hybridization information storage technology, can effectively improve the security of the DNA hybridization storage technology, and promotes the application of the technology in the fields of military affairs, government affairs and commercial encrypted storage.

Description

technical field [0001] The invention belongs to the technical field of DNA storage, in particular to a DNA hybridization information storage and encryption method based on probe sealing and unsealing. Background technique [0002] DNA storage technology is the crystallization of the intersection of life science and information science. DNA is the genetic material selected in the long process of biological evolution. As an information storage material, DNA has the characteristics of extremely long storage time, huge storage information capacity, and strong environmental adaptability, and has great development potential. The current mainstream technology in the field of DNA storage is based on DNA synthesis and sequencing. Although this technology has high information density, it has weaknesses such as poor parallelism, long read and write time, and low encryption performance, which limit the practical application of DNA storage technology. To this end, the applicant team dev...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16B25/00G06F21/60G16B30/00G16B50/00
CPCG16B25/00G16B30/00G16B50/00G06F21/602
Inventor 张翼飞王海华赵椰肖祖颖张东裔刘翟
Owner HUNAN UNIV OF SCI & TECH
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