Rhizoma polygonati chewable tablet and preparation method thereof

A chewable tablet, Polygonatum chinensis technology, which is applied in the field of Polygonatum chinensis chewable tablet and its preparation, can solve the problems that chewable tablet has no anti-oxidation property and is unfavorable for the wide use of chewable tablet, and achieves smooth and delicate surface, smooth and delicate entrance, good anti-oxidation active effect

Pending Publication Date: 2021-11-19
WEST ANHUI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing chewable tablets generally do not have antioxidant properties, which is not conducive to the widespread use of chewable tablets

Method used

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  • Rhizoma polygonati chewable tablet and preparation method thereof
  • Rhizoma polygonati chewable tablet and preparation method thereof
  • Rhizoma polygonati chewable tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Preparation of Rhizoma Polygonatum Extract: Weigh 100g Rhizoma Rhizoma Polygonatum, add distilled water in a ratio of 1:8, carry out 3 times of water extraction, extract 90min each time, combine three filtrates and concentrate in a rotary evaporator, and finally obtain Rhizoma Rhizoma Polygonatum Extract;

[0021] Mix well weighed 0.4g citric acid, 3g lactose, 28g microcrystalline cellulose, 18g pregelatinized starch, and 3.5g hydroxypropyl cellulose in proportion, slowly add an appropriate amount of 35g sealwort extract, and manually Mix uniformly to obtain the soft material of Polygonatum; pass the soft material of Polygonatum through a 24-mesh sieve to make the soft material into particles of Polygonatum; dry the granules of Polygonatum after sieving in a 70°C electric constant temperature blast drying oven for 30 minutes, and pass through 30 minutes after drying. Mesh sieve, then add 0.5g of magnesium stearate and mix evenly, weigh 500g each time of the intact Polygo...

Embodiment 2

[0023] Preparation of Rhizoma Polygonatum Extract: Weigh 100g Rhizoma Rhizoma Polygonatum, add distilled water in a ratio of 1:8, carry out 3 times of water extraction, extract 90min each time, combine three filtrates and concentrate in a rotary evaporator, and finally obtain Rhizoma Rhizoma Polygonatum Extract;

[0024] Mix well weighed 0.45g citric acid, 4g lactose, 29g microcrystalline cellulose, 19g pregelatinized starch, and 3.5g hydroxypropyl cellulose in proportion, slowly add an appropriate amount of 37g sealwort extract, and manually Mix uniformly to obtain the soft material of Polygonatum; pass the soft material of Polygonatum through a 24-mesh sieve to make the soft material into particles of Polygonatum; dry the granules of Polygonatum after sieving in a 70°C electric constant temperature blast drying oven for 30 minutes, and pass through 30 minutes after drying. Mesh sieve, then add 0.5g of magnesium stearate and mix evenly, weigh 500g each time of the intact Polyg...

Embodiment 3

[0026] Preparation of Rhizoma Polygonatum Extract: Weigh 100g Rhizoma Rhizoma Polygonatum, add distilled water in a ratio of 1:8, carry out 3 times of water extraction, extract 90min each time, combine three filtrates and concentrate in a rotary evaporator, and finally obtain Rhizoma Rhizoma Polygonatum Extract;

[0027] Mix well weighed 0.5g citric acid, 5g lactose, 30g microcrystalline cellulose, 20g pregelatinized starch, and 3.5g hydroxypropyl cellulose in proportion, slowly add an appropriate amount of 40g sealwort extract, and manually Mix uniformly to obtain the soft material of Polygonatum; pass the soft material of Polygonatum through a 24-mesh sieve to make the soft material into particles of Polygonatum; dry the granules of Polygonatum after sieving in a 70°C electric constant temperature blast drying oven for 30 minutes, and pass through 30 minutes after drying. Mesh sieve, then add 0.5g of magnesium stearate and mix evenly, weigh 500g each time of the intact Polygo...

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Abstract

The invention is suitable for the technical field of health food, and provides a rhizoma polygonati chewable tablet and a preparation method thereof, the rhizoma polygonati chewable tablet comprises the following raw material components: microcrystalline cellulose, lactose, an acidulant, pregelatinized starch, a lubricant, rhizoma polygonati extract and hydroxy propyl cellulose; the prepared rhizoma polygonati chewable tablets are appropriate in sourness and sweetness, smooth and fine in mouth feel and high in chewiness, and a rhizoma polygonati chewable tablet solution has a scavenging effect on hydroxyl free radicals and superoxide anions, so that the rhizoma polygonati chewable tablets have relatively good antioxidant activity; magnesium stearate is used as the lubricant, so that the prepared granules have good fluidity, and the chewable tablets have smooth and fine surfaces.

Description

technical field [0001] The invention belongs to the technical field of health food, in particular to a sealwort chewable tablet and a preparation method thereof. Background technique [0002] Polygonatum, according to different shapes, is commonly called "rhubarb", "chicken head Polygonatum", and "ginger-shaped Polygonatum". It has the effects of invigorating qi and nourishing yin, strengthening the spleen, nourishing the lungs, and benefiting the kidneys; it is often used for spleen and stomach qi deficiency, body fatigue, lack of stomach yin, dry mouth and lack of food, dry cough due to lung deficiency, coughing up blood due to labor, insufficient essence and blood, waist Sore knees, premature graying of beard and hair, internal heat and thirst. [0003] Chewable tablet refers to the tablet that is chewed or sucked in the mouth to dissolve the tablet and then swallowed; it is convenient to take, and the surface area of ​​the tablet increases after being chewed, which can ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A23L29/00A23P10/28
CPCA23L33/105A23L29/04A23P10/28A23V2002/00A23V2200/30A23V2250/21
Inventor 刘莉彬王顺欢邓辉陈存武宋程
Owner WEST ANHUI UNIV
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