Traditional Chinese medicine composition for treating or improving polycystic ovarian syndrome as well as preparation method and application thereof

Abstract

The invention provides a traditional Chinese medicine composition for treating or improving polycystic ovarian syndrome as well as a preparation method and application thereof The traditional Chinese medicine composition is prepared from the following raw materials of semen cuscutae, placenta hominis, poria cocos, radix puerariae, folium photiniae, radix salviae miltiorrhizae, rhizoma atractylodis fried with bran, prepared radix morindae officinalis, radix rehmanniae praeparata, roasted herba epimedii, spina gleditsiae, cornu cervi, radix gentianae, fried semen cassiae, cleaned fructus crataegi, rhizoma alismatis, folium nelumbinis and salted semen plantaginis. According to the traditional Chinese medicine composition as well as the preparation method and the application thereof provided by the invention, the reproductive disorder and metabolic disorder of the polycystic ovarian syndrome can be improved at the same time, and the SCFA level in intestinal tracts can be obviously improved; the levels of proinflammatory factors such as serum TNF-alpha, IL-1beta and IL-6 are reduced, so that the chronic hyporeactive inflammation is improved; the level of adiponectin receptors in fat, skeletal muscle and ovarian tissue is improved, and finally the insulin resistance of the polycystic ovarian syndrome is obviously improved; and the ovarian function of the polycystic ovarian syndrome and the maturation and development of follicles can be improved.

Description

technical field [0001] The disclosure relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating or improving polycystic ovary syndrome, its preparation method and application. Background technique [0002] Polycystic ovary syndrome (PCOS), as a common reproductive endocrine disorder, affects about 6%-18% of women of reproductive age. PCOS not only affects the development of follicles, leading to menstrual disorders, amenorrhea, infertility and other reproductive disorders, but also interferes with the body's glucose and lipid metabolism pathways, and leads to type 2 diabetes, non-alcoholic fatty liver disease, metabolic syndrome and cardiovascular diseases. The occurrence of long-term complications brings huge mental and economic double pressure to patients. [0003] Since the etiology of PCOS is not yet fully understood, it brings certain difficulties in treatment. At present, the ...

AI Technical Summary

Problems solved by technology

However, there are currently no drugs or treatments that can fully cure or improve PCOS

[0004] PCOS is a major disease that affects women's reproductive health. In patients with PCOS, the intestinal SCFA levels represented by acetic acid and propionic acid are low, and the levels of serum TNF-α, IL-1β, IL-6 and other pro-inflammatory factors are high. Low levels of adiponectin receptors in muscle and ovarian tissue, resulting in poor insulin resistance; and PCOS affects ovarian function and hinders follicular maturation

For the improvement or treatment of PCOS, there is no specific method so far. Therefore, it is urgent to develop a drug that can not only improve the ovarian function of PCOS, but also relieve its metabolic disorders.

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