Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of verbascoside

A technology of acteoside and eluent, applied in the preparation of sugar derivatives, chemical instruments and methods, sugar derivatives, etc., can solve the problems of artificially synthesized actcoside, such as long synthetic route, cumbersome chiral resolution, and many side reactions , to increase the content of verbascoside, facilitate operation, reduce cost and operation difficulty

Pending Publication Date: 2022-01-18
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] As a phenylethanol glycoside component, verbascoside has neuroprotective, anti-tumor, anti-inflammatory and other activities. At present, the main source of verbascoside is from Cistanche deserticola, a plant of the family Cistanche, but it has been listed in China's " National List of Secondary Protected Plants, but artificially synthesized verbascoside has problems such as long synthetic route, many side reactions, cumbersome chiral resolution, low yield and high cost. It is easy to find a common and easy-to-obtain medicinal plant , Simple preparation method is very important

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of verbascoside
  • Preparation method of verbascoside
  • Preparation method of verbascoside

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A method for extracting and separating verbascoside from wine-roasted Ligustrum lucidum, comprising the following steps:

[0024] (1) Weigh 7 kg of Ligustrum lucidum lucidum with wine, and use methanol for cold extraction. The volume of methanol added is 10 times the mass of the medicinal material, and the extraction is performed three times, each time for 72 hours. For extraction, the volume of methanol added is 10 times the mass of the dregs, and the heating and reflux extraction method is used to extract twice, each time for 2 hours. The medicinal residues are filtered out, and the combined extract is concentrated to obtain the extract extract;

[0025] (2) Suspend the extract in water, add ethyl acetate to extract three times with the volume of the suspension and the volume of ethyl acetate at a ratio of 1:1, and recover the ethyl acetate under reduced pressure to obtain the ethyl acetate extract;

[0026] (3) The ethyl acetate extract is separated by silica gel co...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a preparation method of verbascoside, the verbascoside is separated and prepared by taking wine-fried glossy privet fruit as an extraction raw material medicine, the glossy privet fruit is widely distributed in China, the content of verbascoside in wine-fried products is further increased, and compared with a mode of obtaining verbascoside from a national second-level protection plant cistanche, the concept of environmental protection is better met; the extraction and separation method of verbascoside in wine-fried glossy privet fruit is simple in process and convenient to operate, the obtained monomer is high in purity, and compared with an artificial synthesis mode, the cost and the operation difficulty are reduced.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a preparation method of verbascoside. Background technique [0002] Ligustrum lucidum Ait. is the dry ripe fruit of Ligustrum lucidum Ait. It has the effects of nourishing liver and kidney, improving eyesight and black hair. Widely distributed in Zhejiang, Jiangsu, Hunan, Fujian, Guangxi, Jiangxi and Sichuan. The chemical components contained in Ligustrum lucidum mainly include triterpenes, phenylethanol glycosides, iridoids, flavonoids and volatile oils. Wine-roasted Ligustrum lucidum is a wine steamed product of Ligustrum lucidum. After steaming Ligustrum lucidum wine, its effect on treating diabetes and lowering blood sugar is enhanced. Another study shows that the content of verbascoside and salidroside in Ligustrum lucidum The content is enhanced after wine steaming. [0003] As a phenylethanol glycoside component, verbascoside has neuroprotective, a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07H15/18C07H1/08
CPCC07H15/18C07H1/08
Inventor 姜苗苗雷鹏吕佳霖王跃飞张鹏柴欣崔英杨静
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE