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Application of composition containing spica prunellae in preparation of medicine for treating thyroid nodules

A technology of thyroid nodules and Prunella vulgaris, applied in the field of medicine, can solve the problems of increased surgery rate of thyroid nodules, unavoidable changes in thyroid function and nodule recurrence, and poor curative effect of thyroid nodules.

Active Publication Date: 2022-02-01
陕西白鹿制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The current clinical treatment of thyroid nodules is generally based on surgery and thyroxine suppression therapy, and it is known through high-definition ultrasonography that the prevalence of thyroid nodules is as high as 20% to 70%, which also leads to unnecessary The surgical rate of thyroid nodules has increased significantly, and surgery and thyroxine suppression therapy cannot avoid the risks of thyroid function changes and nodular recurrence
At present, there is a problem of poor curative effect of traditional Chinese medicine in the treatment of thyroid nodules

Method used

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  • Application of composition containing spica prunellae in preparation of medicine for treating thyroid nodules

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preparation example Construction

[0047] The preparation method of the composition containing Prunella vulgaris of the present invention comprises the following steps:

[0048] Distilling Prunella vulgaris, Bupleurum, Radix Paeoniae Rubra and Zezhu to obtain the distillate of Prunella vulgaris-Bupleurum-Red Peony-Ezhu and the first remaining component;

[0049] Mix and decoct the first remaining components, turtle shells and oysters to obtain a decoction of Prunella vulgaris-Bupleurum-red peony root-curcuma-turtle shell-oyster;

[0050] Distilling Rhizoma Chuanxiong, Rose and Angelica to obtain Rhizoma Chuanxiong-Rose-Angelica distillate and the second remaining component;

[0051] Mix the second remaining component with Corydalis Corydalis and extract with ethanol to obtain Rhizoma Chuanxiong-Rose Flower-Angelica-Cyrydalis Corydalis extract;

[0052] The Prunella vulgaris-Bupleurum-Red Paeoniae Alba-Ezhu distillate, the Ligusticum chuanxiong-Rose flower-Angelica distillate, the Chuanxiong-Rose flower-Angelica ...

Embodiment 1

[0064] Preparation of compositions containing Prunella vulgaris

[0065] 1. Prepare the following raw materials in parts by mass:

[0066] Prunella vulgaris 297g, Chuanxiong (wine-roasted) 198g, silkworm (bran-roasted) 119g, turtle shell (vinegar-roasted) 297g, Bupleurum (vinegar-roasted) 198g, red peony (wine-roasted) 178g, rose 238g, Curcuma (vinegar 178g, angelica (wine-roasted) 198g, Corydalis (vinegar) 178g and oyster 297g.

[0067] 2. The specific preparation method consists of the following steps:

[0068] S1. Crush silkworms into fine powder; grind turtle shells and oysters into coarse powder, add water to decoct turtle shell powder and oyster powder for 1 hour, set aside;

[0069] S2. Prunella vulgaris, Radix Bupleurum, Radix Paeoniae Rubra, and Zezhu are crushed into coarse powder, and steam distillation is used to extract volatile oil; medicinal residues and water decoction are mixed with medicinal residues and water decoction of turtle shells and oysters, and dec...

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to an application of a composition containing spica prunellae in preparation of a medicine for treating thyroid nodules. According to the composition containing the spica prunellae, spica prunellae serves as a monarch drug, rhizoma chuanxiong, stiff silkworm, turtle shell, radix bupleuri, radix paeoniae rubra, rose, curcuma zedoary, angelica sinensis, corydalis tuber and oyster are matched, and curative effects of soothing liver, relieving depression and promoting blood circulation to remove blood stasis are achieved. Specific cases and animal experiments show that the composition containing the spica prunellae provided by the invention can treat thyroid nodules caused by qi stagnation, blood stasis and phlegm coagulation, and has no toxic or side effect.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to the application of a composition containing Prunella vulgaris in the preparation of medicines for treating thyroid nodules. Background technique [0002] Thyroid nodules refer to independent lesions that occur in the thyroid gland that are different from the normal tissue structure. It is mainly manifested as one or more lumps with abnormal tissue structure in the thyroid gland, which can move up and down with swallowing movements. It is a common thyroid system disease. In the category of "gall disease" in traditional Chinese medicine. [0003] Through long-term research, it has been found that qi stagnation, phlegm coagulation, and blood stasis in front of the neck are the basic pathogenesis of gall disease. The lesion site is mainly in the liver and spleen. Liver depression leads to stagnation of qi, spleen injury leads to stagnation of qi, stagnation of qi lead...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/536A61K36/9066A61P43/00A61K35/586A61K35/618A61K35/64
CPCA61K36/536A61K36/236A61K35/64A61K35/586A61K36/233A61K36/71A61K36/65A61K36/738A61K36/9066A61K36/232A61K36/66A61K35/618A61P43/00A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 常凯张辉刘玉桥
Owner 陕西白鹿制药股份有限公司
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