Full-automatic digital microfluidic analysis platform

Abstract

The invention discloses a full-automatic digital micro-fluidic analysis platform, which comprises a mounting base, and a magnetic separation control module, a chip supporting plate, a chip temperature control module, a chip driving electric needle module and a multi-path fluorescence detection system, which are arranged on the mounting base; wherein the chip supporting plate is used for supporting the digital micro-fluidic chip; the magnetic separation control module, the chip temperature control module, the multi-channel fluorescence detection system and the chip driving electroacupuncture module are respectively used for being matched with a digital micro-fluidic chip; the platform further comprises a laser emitter installed on the chip driving electric needle module, wherein an output cable of the laser transmitter is connected with the multi-path fluorescence detection module. The scheme can be adapted to digital micro-fluidic chips of various specifications and types, the functions of liquid drop driving, temperature control, magnetic bead separation, multi-path multi-fluorescence detection and the like of the chip are completed on a platform, and full-automatic test analysis is realized on the micro-fluidic chip; besides, the experiment steps can be reduced, reaction time is saved, reaction efficiency is improved, reagent cost is reduced, and the market blank can be filled up.

Description

technical field [0001] The invention relates to the technical field of digital microfluidics, in particular to a fully automatic digital microfluidic analysis platform with magnetic separation, fluorescence detection and temperature control. Background technique [0002] Digital microfluidics (DMF) is a new type of droplet manipulation technology. Common droplet driving methods include dielectric wetting, dielectrophoresis, surface acoustic wave, electrostatic force, and magnetic force. Compared with traditional microfluidic chips based on microchannels, DMF technology retains the characteristics of low sample consumption, fast heat transfer speed, high parallelism and automation, and does not rely on micropumps, microvalves or micromixers Components such as components do not even need complex three-dimensional fluid channels, and have the advantages of simple construction and dynamic configuration, so they are especially suitable for biological and chemical micro-analysis s...

AI Technical Summary

Problems solved by technology

[0003] With the continuous improvement of digital microfluidic chip and its system technology, it is urgent to develop a matching digital microfluidic platform, which can realize various complex biological analysis experiments on the digital microfluidic chip. The lack of such equipment

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