Composition for preparing burn and wound dressing as well as preparation and preparation method thereof

The invention belongs to the technical field of medical drugs, and particularly relates to a composition for preparing a burn wound dressing and a preparation and a preparation method thereof. According to the burn and wound dressing, silk fibroin serves as an antioxidant and is loaded to a framework of chitosan-water absorption molecules, and the porous asymmetric burn and wound dressing with the antioxidant and moisturizing functions is prepared. The burn and wound dressing consists of silk fibroin, a skeleton and an auxiliary material in a mass ratio of 1: (2-10): (0.1-5), the framework is a chitosan-water absorption polymer framework; the mass ratio of the chitosan to the water-absorbing polymer is 1: (0.1-5). The burn wound dressing disclosed by the invention can promote the healing of a chronic wound surface difficult to heal in an oxidative stress microenvironment, and is a novel composite dressing integrating the advantages of high moisture retention, high strength, air permeability, barrier property, easy uncovering property and the like. The dressing is prepared through freeze-drying, the preparation process is simple, the cost is low, the treatment effect is outstanding, the safety of burns and wounds is good, and the dressing has remarkable medical value and industrialization potential.