Chinese medicine for treating primary osteoporosis resulted from deficiency of liver and kidney and its preparation method

A technology for osteoporosis, liver and kidney insufficiency, applied in the direction of unknown raw materials, bone diseases, drug combinations, etc., can solve the problems of easy rebound after drug withdrawal, serious side effects, etc., and achieve the effect of no toxic side effects and safe medication

Inactive Publication Date: 2005-12-21
JIANMIN PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the commonly used western medicines are mainly calcium, estrogen, calcitonin and other drugs that are beneficial to calcium absorption and inhibition of osteolysis. In the treatment of osteoporosis, it mainly focuses on overall regulation and has obvious advantages

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Take 10Kg of Moutan cortex and add water to distill for 4 hours to extract paeonol, separate paeonol and dry at low temperature, grind it into fine powder for later use; mix the distilled Moutan cortex dregs with Rehmannia glutinosa 30Kg, dog ridge 10Kg, dogwood 10Kg, yam 10Kg , Angelica 10Kg, Epimedium 10Kg, and calcined oyster 10Kg are decocted twice with water, combined and concentrated into an extract with a relative density of 1.30, mixed with an appropriate amount of starch and granulated, and added an appropriate amount of prepared granules Magnesium stearate is used as lubricant, and tabletting promptly gets tablet of the present invention.

[0033] The traditional Chinese medicine tablet of the present invention has the functions of nourishing the liver and kidney, strengthening tendons and bones, and is mainly used for primary osteoporosis caused by deficiency of liver and kidney. doctor's order.

Embodiment 2

[0035]Take 30Kg of Moutan cortex and add water to distill for 4 hours to extract paeonol, separate paeonol and dry at low temperature, stir paeonol and 4 times the amount of β-cyclodextrin in water for 1 and a half hours, the temperature is controlled at 40 ° C, and then Cool to precipitate crystals, filter, dry, and crush the crystals to obtain the clathrate of paeonol for later use; take 20Kg of Cornus officinalis, 30Kg of Angelica sinensis, and 10Kg of Epimedium and extract them with ethanol. The specific method is: put the above three medicinal materials in a heat reflux device Add 50% ethanol to reflux twice, combine the medicinal liquid to recover ethanol and concentrate under reduced pressure to obtain extract; weigh 70Kg rehmannia glutinosa, 15Kg yam, 20Kg dog ridge and 40Kg calcined oyster, combine with the dregs of the ethanol reflux part, add water to decoct 2 times, combine the medicinal solution and concentrate under reduced pressure to the extract; combine the two...

Embodiment 3

[0037] In this embodiment, the preparation method, functions and indications, usage and dosage of the medicine are the same as in Example 2, except that the dosage of the medicinal materials in the prescription is different. The dosage of the medicinal materials is: Moutan bark 20Kg, dogwood 25Kg, angelica 25Kg, epimedium 25Kg, Rehmannia glutinosa 50Kg, yam 15Kg, dog ridge 25Kg and calcined oyster 38Kg.

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Abstract

The invention relates to a traditional Chinese medicine for treating primary osteoporosis with liver and kidney deficiency syndrome and a preparation method thereof. Its ingredients are composed of rehmannia glutinosa, dogwood, dog ridge, epimedium, yam, angelica, moutan bark, and calcined oyster. The preparation method comprises several steps of distilling moutan cortex, extracting medicinal materials, concentrating medicinal liquid, and forming preparations.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine, in particular, it is a traditional Chinese medicine for treating primary osteoporosis with liver and kidney deficiency syndrome, and the invention further provides a preparation method thereof. Background technique [0002] Osteoporosis is a disease of abnormal bone metabolism. Its pathogenesis is not yet clear. It is generally believed to be related to human aging and endocrine disorders. It has a high incidence rate and great harm, and is currently listed as a common disease of the elderly alongside arteriosclerosis and tumors. At present, the commonly used western medicines are mainly calcium, estrogen, calcitonin and other drugs that are beneficial to calcium absorption and inhibition of osteolysis. In the treatment of osteoporosis, it mainly focuses on overall regulation and has obvious advantages. The effect of traditional Chinese medicine is mainly the result of th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P19/10
Inventor 熊富良张惠明黄志军曹智华徐绍新许沛虎梁前荣鞠瑞芬
Owner JIANMIN PHARMA GRP CO LTD
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