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Use of Hubei erectum in preparing anti-depression, anti-anxiety or/and brain improving medicine

An anti-anxiety and anti-depression technology, applied in the fields of drug combination, food science, pharmaceutical formula, etc., can solve the problem of improving memory without anti-depression and anti-anxiety, and achieve the effect of improving learning and memory and anti-anxiety learning and memory.

Inactive Publication Date: 2006-06-14
SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since Forsythia chinensis is a newly discovered new resource (new taxon), there are no reports about its anti-depression, anti-anxiety, and memory improvement in existing technologies and literatures, nor is it used for depression, anxiety, and dementia. Any record of disease treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take 500g of the coarse powder of Forsythia forsythiae in Hubei, leaching with 90% ethanol at room temperature for 3 times under stirring from time to time, each time for 24 hours, and the amount of solvent for each time is 3L, combine the extracts, concentrate under reduced pressure to recover the solvent, and freeze-dry to obtain Hubei The extract of Forsythia japonicus contains 0.33% hypericin and 38.60% total flavonoids.

Embodiment 2

[0019] Take 300g of Hubei forsythia coarse powder, add methanol, and ultrasonically extract 3 times below 40°C, each time for 30min, and each time the dosage is 1.5L. Filter, combine the extracts, and recover the solvent under reduced pressure to obtain the extract. Wherein the hypericin content is 0.61%, and the total flavonoid content is 26.9%.

Embodiment 3

[0021] Take 400g of Hubei forsythia coarse powder, add acetone, and ultrasonically extract 3 times below 40°C, each time for 30min, and each time the dosage is 2.4L. Filtrate, combine the extracts, recover the solvent under reduced pressure to obtain the extract, wherein the content of hypericin is 0.54%, and the content of total flavonoids is 31.5%.

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PUM

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Abstract

The present invention relates to the application of plant Hubei erectum in preparing medicine and food for resisting depression, resisting anxiety and / or promoting intelligence growth. Experiments show that Hubei erectum or its extract may be used as effective component in preparing medicine for depression, sleep disturbance, senile dementia, hypomnesia and other diseases and as additive in producing anti-senility food and health food for sub-health with depression, sleep disturbance, amnesia and other diseases and health people.

Description

technical field [0001] The present invention relates to the application of Hubei forsythia japonicus, in particular to the application of Hubei forsythia japonicus or its extract in the preparation of antidepressant, anti-anxiety or / and nootropic drugs or food. Background technique [0002] Hubei small forsythia (Hypericum hubeiense L.H.Wu et D.P.Yang) is the perennial herbaceous plant of the genus Hypericum (Hypericum L.) of Garciniaceae, and is a new taxon discovered by inventor Yang Depo, etc. [Wu Lihong, Yang Depo, etc. Silk peach (Garciniaceae) new plant, Acta Plant Taxonomy, 2003], also known as large pair of leaves. Since Forsythia chinensis is a newly discovered new resource (new taxon), there are no reports about its anti-depression, anti-anxiety, and memory improvement in existing technologies and literatures, nor is it used for depression, anxiety, and dementia. Any record of disease treatment. Contents of the invention [0003] The object of the present inven...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/634A61P25/24A61P25/22A61P43/00A61K133/00A61K127/00A23L33/105
Inventor 杨得坡王冬梅白洁甘良春
Owner SUN YAT SEN UNIV