Medicine for treating prostatitis

A prostatitis and drug technology, applied in the field of plant materials, can solve problems such as failure to achieve an ideal therapeutic effect, unclear etiology, and insufficient understanding of the pathophysiological mechanism of chronic nonbacterial prostatitis

Active Publication Date: 2006-11-15
西安万隆制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, chronic nonbacterial prostatitis accounts for 64%, and its etiology is still unclear. Based on the literature review on chronic nonbacterial prostatitis, it is believed that due to the understanding of the etiology and pathophysiological mechanism of chronic nonbacterial prostatitis Not enough, therefore, the ideal treatment effect has not yet been achieved
Chronic non-bacterial prostatitis accounts for the vast majority of prostatitis. At present, some progress has been made in its etiology, epidemiology, diagnosis and treatment. However, because its etiology and pathogenesis have not been fully elucidated, Western medicine often lacks thorough and effective treatment Therapeutic drugs lead to low cure rate and high recurrence rate of the disease, which obviously affects the quality of life of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Taking the production of 1000 tablets of the pharmaceutical tablet product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0047] Scutellaria barbata 682.76g

[0048] Noodles  546.21g

[0049]Radix Paeoniae Rubra 364.14g

[0050] Patrinia 364.14g

[0051] Sichuan Ayurvedic Knuckle 227.59g

[0052] Orange core 227.59g

[0053] Wang Buliuxing 227.59g

[0054] Sodium carboxymethyl starch 100g

[0055] Talc powder 7.5g

[0056] Add starch to 500g

[0057] Scutellaria barbata and other Qiwei medicinal materials are extracted twice with 70% ethanol under reflux, the first time is 8 times the amount, the second time is 6 times the amount, refluxed for 2 hours, filtered, combined with the second filtrate, concentrated under reduced pressure to a relative density of 1.20~ 1.25 (measured at 60°C), dry under r...

Embodiment 2

[0099] Taking the production of 1000 tablets of the pharmaceutical tablet product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0100] Scutellaria barbata 621.18g

[0101] Noodles 621.18g

[0102] Paeoniae Rubra 465.88g

[0103] Patrinia 465.88g

[0104] Sichuan Ayurvedic Knuckle 155.29g

[0105] Orange core 155.29g

[0106] Wang Buliuxing 155.29g

[0107] Sodium carboxymethyl starch 100g

[0108]Talc powder 7.5g

[0109] Add starch to 500g

[0110] Its preparation process is carried out according to the preparation process of the tablet of the present invention. Each tablet weighs 0.5g, contains crude drug 5.28g per gram, takes 2 times a day, 4 tablets each time.

[0111] Taking the production of granule product 1000g of the present invention as an example, the used Chinese medicine raw materials and au...

Embodiment 3

[0152] Taking the production of 1000 tablets of the pharmaceutical tablet product of the present invention as an example, the used Chinese medicine raw materials and auxiliary materials and their proportioning ratio are:

[0153] Scutellaria barbata 720g

[0154] Noodles  480g

[0155] Radix Paeoniae Alba 360g

[0156] Patrinia 360g

[0157] Sichuan Ayurvedic Knuckle 240g

[0158] Orange core 240g

[0159] Wang Buliu Xing 240g

[0160] Sodium carboxymethyl starch 100g

[0161] Talc powder 7.5g

[0162] Add starch to 500g

[0163] Its preparation process is carried out according to the preparation process of the tablet of the present invention. Each tablet weighs 0.5g, and each gram contains 5.28g of traditional Chinese medicine raw materials. Take 2 times a day, 4 tablets each time.

[0164] Taking the production of granule product 1000g of the present invention as an example, the used Ch...

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PUM

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Abstract

A medicine for treating prostatitis, comprising (amount by weight): 4-30 parts of Scutellaria barbata, 4-20 parts of Fenzhi, 3-15 parts of Radix Paeoniae Rubra, 3-15 parts of Patrinia, and Achyranthes bidentata 1 to 10 parts, 1 to 10 parts of Tangerine Pit, 1 to 10 parts of Wang Buliuxing, prepared according to conventional preparation methods. The drug efficacy test of the present invention proves that it can reduce the prostate viscera coefficients of two kinds of model rats with chronic non-bacterial prostatitis caused by Xiaozhiling injection and cross vegetable gum, and improve the pathological and histological changes of the model rats; Reduce the weight of cotton ball granuloma in rats, reduce the swelling rate of paws after egg white-induced inflammation; inhibit xylene-induced ear swelling in mice; increase the pain threshold of mice induced by hot plate method; reduce the number of writhing in mice induced by acetic acid. It shows that it has anti-inflammatory and analgesic effects, and has a therapeutic effect on chronic non-bacterial prostatitis in rats.

Description

technical field [0001] The invention belongs to the technical field of medical preparations containing raw materials or their reaction products with unknown structures, and specifically relates to materials derived from plants. Background technique [0002] Prostatitis has always been one of the main problems in andrology and urology. The incidence rate in the population varies greatly, and the results of various studies are not the same. The health statistics of the International Health Center show that the incidence of prostatitis was about 25% from 1977 to 1978; 35% to 50% of men will be affected by prostatitis at some point in their lives. Pavone et al. reported that nearly 18.9% of Italian urology outpatients visited a doctor due to recurrent clinical symptoms of prostatitis. In my country, prostatitis accounts for about 1 / 3 of the total number of outpatients in urology and andrology. Prostatitis is a common disease in adult men, which has a serious impact on the phys...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61K36/539A61K36/71A61K36/185A61K36/21A61K36/752A61K36/36A61P13/08
Inventor 马耀茹窦建卫
Owner 西安万隆制药股份有限公司
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