Composition for treaitng contact lens and its application

A contact lens and composition technology, applied in the direction of chemistry, etc., can solve the problems of increasing inconvenience, residual care solution ingredients, eye irritation, etc., to increase lubricity and moisturizing, keep eyes moist, and increase eye comfort. Effect

Inactive Publication Date: 2003-01-15
上海卫康光学眼镜有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this has another problem: due to the high water affinity, the lens will retain and absorb some care solution ingredients (if the wearer does not care properly, the residual ingredients will be more), and as the lens is worn into the eye again, these ...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example

[0027] Compositions with different dosages and molecular weights of sodium hyaluronate were prepared according to the formula described in Table 2 and according to the method of Example 1, and their effects on cell growth and use comfort were tested. Because cell experiments can accurately and objectively reflect the potential toxicity of test samples, this method is often used in the industry as a biocompatibility evaluation test for contact lens care solutions, such as the ISO9363-1 test method (reaction rating is 0-4 level, the lower the level, the better the biocompatibility of the test material) or use the cell proliferation degree method of GB16886 to measure the biocompatibility of the experimental material with the relative cell proliferation degree (RGB value), the higher the proliferation degree, the corresponding The better the capacity. The present invention adopts these two test methods simultaneously to test and evaluate Examples 3-6 and Comparative Exampl...

Embodiment 7-10

[0035] The composition solutions of Examples 7-10 were prepared according to the formula in Table 4 and the method of Example 1, and the protein removal rate and bactericidal efficiency of the composition solutions were tested.

[0036] Compositions with different buffer compositions were used to test the protein-removing cleaning efficiency and bactericidal efficiency of the above-mentioned examples (the method for the bactericidal efficiency experiment adopted the method of GB15981-1995). Comparative example 2 (normal saline) does not have any bactericidal ability, and each embodiment is all more than 99.99% to the effective bactericidal rate of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and also more than 90% to the bactericidal rate of Candida albicans.

[0037] Investigating the cleaning ability of lens deposits can be compared by the following method: use the composition solution to be tested to treat the soft lens that has been pretreated with album...

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PUM

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Abstract

A composition for treating contact lens is a nursing solution containing sodium hyaluronate, and can be used for cleaning, sterilizing and storing contact lens, and wetting eye and lens, preventing eye's desiccation and irritation.

Description

technical field [0001] The invention relates to a composition for cleaning, disinfecting, storing contact lenses and as an intraocular moistening solution and its application. technical background [0002] In general, contact lenses are roughly divided into two types: hard contact lenses and soft contact lenses. The water content of hard contact lenses is less than 10%, which is quite durable. At the same time, the nature of the lens material does not carry charges. Therefore, when wearing this kind of lenses, there is no need to worry about the lenses absorbing tears such as proteins, lipids or Substances such as microorganisms can cause discomfort and damage to the eyeball, so ophthalmologists generally agree to recommend this kind of lens to the wearer. However, due to poor deformation characteristics of hard contact lenses, strong foreign body sensation in the eyes, and poor adaptability to initial wear, consumers are more inclined to choose soft contact lenses with goo...

Claims

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Application Information

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IPC IPC(8): A61L12/14
Inventor 钟海波
Owner 上海卫康光学眼镜有限公司
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