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Medicinal composition for treating psoriasis

A composition and technology for psoriasis, applied in the directions of drug combinations, skin diseases, pharmaceutical formulations, etc., can solve problems such as no reports yet

Inactive Publication Date: 2004-03-03
CHONGQING HUAPONT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After retrieval, so far this compound preparation has no report in the existing literature

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 Compound Tazarotene Betamethasone Dipropionate Cream Ingredients: Tazarotene 0.05g Betamethasone Dipropionate 0.064g Liquid Paraffin 28g Vaseline 10g Cetyl Alcohol 4g Stearyl Alcohol 1.5g Monostearic Acid Glyceride 7g Pingping plus O 20 0.6g Span-60 6g propylene glycol 5g benzyl alcohol 1g distilled water to 100g

Embodiment 2

[0015] Example 2 Compound Tazarotene Betamethasone Dipropionate Cream Ingredients: Tazarotene 0.1g Betamethasone Dipropionate 0.064g Liquid Paraffin 33g Beeswax 8g Isopropyl Palmitate 6gSpan-60 8.4gTween-80 1.6 g propylene glycol 5g benzyl alcohol 1g potassium sorbate 0.05g distilled water to 100g

Embodiment 3

[0016] Example 3 Compound Tazarotene Fluticasone Propionate Cream Ingredients: Tazarotene 0.05g Fluticasone Propionate 0.05g Silicone Oil 30g Petrolatum 8g Cetyl Alcohol 6g Glyceryl Monostearate 6.5g Pingpingjia O 20 0.55g Span-60 3.8g propylene glycol 4.5g benzyl alcohol 1g distilled water to 100g

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PUM

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Abstract

A composite medicine in the form of ointment and gels for treating psoriasis contains Tazhuluoding, betamethasone dipropionate and pharmacologically receptable auxiliary. Its advantages are high curative effect and high safety.

Description

Technical field: [0001] The invention relates to a pharmaceutical composition for treating psoriasis, in particular to an ointment and a gel containing tazarotene and adrenocortical hormone drugs. Background technique: [0002] Tazarotene and adrenal corticosteroids are commonly used in the clinical treatment of dyskeratotic skin diseases. Tazarotene can cut off the three pathological processes of such skin diseases: ① hyperplasia of keratinocytes in the basal layer; ② parakeratosis; ③ inflammatory response of the epidermis; In the early stage of inflammation, it can reduce exudation, edema, telangiectasia, leukocyte infiltration and phagocytosis, thereby improving symptoms such as redness, swelling, heat, and pain. In the later stage, it can inhibit the proliferation of capillaries and fibroblasts, continue the formation of granulation tissue, and prevent scarring Formation, reduce inflammation, corticosteroids and tazarotene combined treatment of psoriasis can shorten the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4436A61K31/56A61K31/573A61K31/58A61P17/06
Inventor 魏向阳朱学琳王永军张颖李娟
Owner CHONGQING HUAPONT PHARMA
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