Compsns. for preparing external carbon dioxide agents

A technology of carbon dioxide and external preparations, which can be applied in the directions of non-active components of polymer compounds, drug combinations, cosmetic preparations, etc., and can solve problems such as unknown

Inactive Publication Date: 2004-08-11
谷 光正
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the dispersion and dissolution of thickeners, or formulations for promoting swelling are also known, but in the composition for preparing carbon dioxide external preparations, it is possible to easily prepare a high-viscosity carbon dioxide external preparation composition in a short time, not yet known

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Manufacture of Granules:

[0060] Using 50 parts by weight of lactose as a water-soluble dispersant, 30 parts by weight of citric acid as a water-soluble acid, 7 parts by weight of processed starch, 3 parts by weight of dextrin and 10 parts by weight of potato starch as a thickener, using water as a wet extrusion solvent The compression granulation method produces porous columnar particles with a length of about 4 mm and a diameter of about 1 mm. The yield of the pellets was about 60%.

[0061] Manufacture of viscous compositions:

[0062] Dissolve 4.0 parts by weight of sodium bicarbonate as a carbonate in 91.5 parts by weight of purified water, and slowly add 1.5 parts by weight of sodium alginate and carboxymethyl cellulose as a thickener while slowly heating to 60°C 3.0 parts by weight of sodium; and stirring to dissolve, let stand overnight after dissolving, and make a viscous composition after cooling to room temperature.

[0063] The above-mentioned granules a...

Embodiment 2

[0065] Manufacture of Granules:

[0066] Use 65 parts by weight of xylitol as a water-soluble dispersant, 15 parts by weight of sodium dihydrogen phosphate as a water-soluble acid, 10 parts by weight of dextrin and 10 parts by weight of cornstarch as a thickener, and utilize water as a wet extrusion process of a solvent. The granulation method produces porous columnar granules with a length of about 4mm and a diameter of about 1mm. The yield of the pellets was about 65%.

[0067] Manufacture of viscous compositions:

[0068] Dissolve 1.5 parts by weight of sodium bicarbonate as carbonate in 92.5 parts by weight of purified water, 0.1 part by weight of methyl p-hydroxybenzoate as a preservative; part, 0.1 part by weight of amomile essence, 0.1 part by weight of chai sandalwood essence, and 0.1 part by weight of perilla essence, and after making it uniformly dispersed, while slowly heating to 60°C, slowly add sodium alginate as a thickener 2.5 parts by weight and 2.0 parts by...

Embodiment 3

[0071] Manufacture of Granules:

[0072] Use 60 parts by weight of lactose as a water-soluble dispersant, 20 parts by weight of citric acid as a water-soluble acid, 10 parts by weight of dextrin, 10 parts by weight of potato starch as a thickener, and water as a solvent. After blending, wet extrusion The granulation method produces porous columnar particles with a length of about 4mm and a diameter of about 1mm. The yield of the pellets was about 65%.

[0073] Manufacture of viscous compositions

[0074] Dissolve 3.0 parts by weight of sodium bicarbonate as carbonate in 88.5 parts by weight of purified water, and add each 0.1 part by weight of cypress essence, ginseng essence, perilla essence, purple root essence, and rosemary essence as other additives, 3.0 parts by weight of 1,2-pentanediol as a preservative, slowly heated to 60°C, while slowly adding 3.0 parts by weight of sodium alginate and 2.0 parts by weight of sodium carboxymethylcellulose as a thickener, stirring M...

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Abstract

Compositions for preparing external carbon dioxide agents comprising a granular material containing a water-soluble acid(s), a thickener(s) and a water-soluble dispersant(s) as the essential components wherein the thickener(s) is (are) mixed with the water-soluble acid(s) and the water-soluble dispersant(s), and a viscous material, which consists of a carbonate(s), water and a thickener(s) as essential components; to be mixed with the said granular material at use, by which an external carbon dioxide agent can be prepared easily in a short period of time. The prepared external carbon dioxide agent, containing much carbon dioxide evenly all over, has sufficient viscosity and can form a coating film on the surface in contact with air, therefore the diffusion of carbon dioxide is suppressed, the applied agent does not droop and its thickness is not reduced when applied to skin or mucosa; and the agent shows potent and quick cosmetic and medical effects.

Description

technical field [0001] The invention relates to a composition for preparing a carbon dioxide external preparation with cosmetic effect and medical effect. Background technique [0002] Carbon dioxide absorbed percutaneously and through mucous membranes promotes blood flow in the skin, subcutaneous tissue, and muscles, and activates metabolism to obtain cosmetic and medical effects. Carbonated springs have been used all over the world for the purpose of obtaining these effects. and various studies conducted on it have drawn clear conclusions. For example, in terms of medical effects, in the treatment of decubitus, Hiyoshi and others have proposed that artificial carbonated springs are effective for refractory decubitus (Jiji Junji, about the treatment of artificial carbonated spring baths for decubitus, General Physiotherapy 17(8):605-609, 1989). [0003] In order to easily obtain the beauty and medical effects brought about by external use of carbon dioxide, carbon dioxide...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/04A61K8/19A61K9/06A61K9/16A61K9/46A61K31/19A61K33/00A61K47/12A61K47/36A61K47/38A61K47/42A61L26/00A61P1/02A61P17/02A61P17/12A61P19/02A61P21/00A61P25/00A61Q19/00A61Q19/02A61Q19/06
CPCA61K33/00A61K9/0007A61K31/19A61K47/38A61K8/19A61K9/1652A61K2800/88A61K47/12A61Q19/06A61K9/0014A61K2800/222A61L26/0061A61K2800/22A61L26/0004A61K9/1617A61Q19/00A61K47/42A61K9/06A61Q19/02A61K47/36A61K8/0204A61K8/0225A61P1/00A61P1/02A61P17/00A61P17/02A61P17/04A61P17/06A61P17/08A61P17/10A61P17/12A61P17/16A61P19/00A61P19/02A61P21/00A61P25/00A61P25/02A61P25/04A61P29/00A61P33/08A61P37/08A61P39/02A61P7/02A61P9/00A61P9/10
Inventor 田中雅也
Owner 谷 光正
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