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Composite panaxadiol and saponin with physiologic activity and its use and preparation

A technology of ginseng diol saponin and physiological activity, which is applied in the direction of organic active ingredients, medical preparations containing active ingredients, pharmaceutical formulas, etc., and can solve problems such as unseen compound research

Inactive Publication Date: 2005-02-23
玉溪维和香格喜玛生物技术有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are some research reports on each single effective extraction part, but there is no compound research identical with the patent application of the present invention

Method used

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  • Composite panaxadiol and saponin with physiologic activity and its use and preparation
  • Composite panaxadiol and saponin with physiologic activity and its use and preparation
  • Composite panaxadiol and saponin with physiologic activity and its use and preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1. Compound ginsengdiol type saponin granules

[0033] Recipe (1000 packs):

[0034] Ginsengdiol saponins group (Rb 1 =52.5%) 12.5g

[0035] Gastrodia extract (containing 14.0% gastrodin) 9.5g

[0036] Tea polyphenols 20.0g

[0037] Vitamin C 15g

[0038] Vitamin E 3g

[0039] Sucrose 3100g

[0040] Dextrin 380g

[0041] Ethanol

[0042] According to ordinary granulation method, the granules are divided into 1000 bags (about 3.5g per bag). Take one sachet at a time, once a day (before bed).

Embodiment 2

[0043] Example 2. Compound ginsengdiol type saponin capsules

[0044] Formula (1000 capsules):

[0045] Ginsengdiol saponins group (Rb 1 = 82.5%) 22.5g

[0046] Gastrodia extract (containing 68.4% gastrodin) 10.5g

[0047] Tea polyphenols 15.0g

[0048] Vitamin C 19g

[0049] Vitamin E 4g

[0050] Plant refined oil 400g

[0051]The solid part of the active ingredient is mixed uniformly, ultra-fine (>2000 mesh), vitamin E is added to the refined oil, and then prepared according to the preparation method of ordinary capsules. The content of each pellet weighs about 470 mg, and 1000 pellets can be obtained.

Embodiment 3

[0052] Example 3. Compound ginsengdiol saponin dripping pills

[0053] formula:

[0054] Ginsengdiol saponins group (Rb 1 = 82.5%) 30g

[0055] Gastrodia extract (containing 68.4% gastrodin) 10g

[0056] Tea polyphenols 8g

[0057] PEG-6000 300g

[0058] The solid part of the active ingredient is mixed uniformly, ultra-fine (>2000 mesh), added to the matrix PEG-6000, heated to melt into a liquid state, dripped into the liquid paraffin condensate under heat preservation conditions, and controlled a certain speed to make it solidify Into a round ball. Get dripping pills and determine the content of each pill to take Rb each time 1 The total should be 24mg to determine the dosage.

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PUM

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Abstract

A bioactive compound panoxadiol saponin contains panoxadiol saponins, gastrodin and tea polyphenol. It can be used to prepare the medicines or functional food for repairing the damaged brain cells or cerebronerve cells and treating insomnia and amnesia.

Description

Technical field [0001] The invention relates to a compound ginsengdiol saponin with physiological activity and its preparation and application. Background technique [0002] Ginseng (Korean ginseng), American ginseng and Panax notoginseng (also known as Ginseng notoginseng, Tianqi, and southern ginseng) are all plants of the genus Araliaceae, and their roots, leaves, flowers, etc. have medicinal values, mainly containing ginsenosides Other substances. According to research data, it is proved that the ginsenosides, panax ginseng saponins and panax notoginseng saponins extracted from various plants are mainly composed of Rb 1 Mainly ginsengdiol saponins and Rg 1 Mainly composed of ginseng triol-type saponins. Diol-type saponins and triol-type saponins have similarities and differences, and they are even opposite in function of the nervous system. Both have similar effects in improving the hemodynamics of blood circulation, reducing blood viscosity, and reducing blood lipids. At pre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K31/704A61P25/00
Inventor 杨兆祥艾黎
Owner 玉溪维和香格喜玛生物技术有限责任公司
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