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Body temperature elevating agents

A technology that raises body temperature and height, is applied in food preparation, food science, application, etc., and can solve problems such as unsustainable effects

Inactive Publication Date: 2005-07-13
THE NISSHIN OILLIO GRP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But using these methods, although it can promote blood circulation and make the body warm after a while, the effect cannot last long.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0144] Example 1 Expression of UCP-2

[0145]Fat accumulated in the body, for example, is broken down into free fatty acids by the action of hormone-sensitive lipase. This free fatty acid is converted into heat energy by burning in the mitochondria. UCP-2 has the greatest influence on the conversion of the above-mentioned free fatty acids into heat energy. UCP-2 is expressed on the membranes that form mitochondria. UCP-2 is a specialized channel that short-circuits the chemical reactions inside and outside the membranes that form mitochondria. That is, UCP-2 short-circuits free fatty acids with other chemical reactions on the mitochondrial membrane, converting them into heat. Therefore, when the expression of UCP-2 is high, free fatty acids will be burned smoothly. In this example, rats were used for experiments, and it was confirmed that the oral administration of medium-chain fatty acid triglycerides, which is the main component of the present invention, is effective for...

Embodiment 2

[0155] Embodiment 2, the expression measurement of UCP-2

[0156] With the same purpose and method as in Example 1, the expression of UCP-2 in various parts of the mouse was determined. However, in this example, the fasting time before the measurement was divided into 6 hours and 18 hours. The measurement sites were the liver, the fat around the epididymis, and the subcutaneous fat, and the above-mentioned UCP expression level was achieved by the same method as in Example 1, and the results are shown in Table 2.

[0157] Fasting time (h)

the liver

fat around epididymis

subcutaneous fat

6h

LCT

85.4±4.0

40.1±6.2

92.7±11.9

MCT

78.0±6.0

47.0±11.5

244.0±44.7

18h

LCT

41.8±0.4

107.8±22.4

199.8±36.3

MCT

70.0±7.9

249.0±60.0

252.1±44.6

[0158] LCT: Soybean oil addition group MCT: Oil and fat composition addition grou...

Embodiment 3

[0160] Example 3 Comparison of UCP-2 expression in various parts

[0161] In the body, when fat etc. are burned, fat is burned first, and then skeletal muscle is burned. This example is to compare and study the fat burning patterns of various parts of the body when taking medium-chain fatty acid triglycerides and not taking them. The study was carried out by comparing the changes of UCP expression in various parts with time.

[0162] Research methods

[0163] After 6 weeks of Wistar male mice were pre-fed for 1 week, they were divided into two groups (20 each), that is, the soybean oil group and the oil composition group containing 100% medium-chain fatty acid triglycerides were added, and the whole corn was fed freely. The experimental food and water of AIN93 standard sucrose were replaced with starch, and the body weight and intake over time were measured. After feeding for 6 weeks, mice in each group were slaughtered after 6 hours of fasting, and used to determine the exp...

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PUM

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Abstract

The invention provides an agent for raising body temperature, beverages and food for raising body temperature and the like. The present invention relates to a body temperature raising agent, a beverage and a food for raising body temperature, which take medium-chain fatty acid and / or glycerin fatty acid ester containing medium-chain fatty acid, especially medium-chain fatty acid triglyceride fatty acid ester as active ingredients.

Description

technical field [0001] The invention relates to a body temperature raising agent which takes medium-chain fatty acid and / or glycerin fatty acid ester containing medium-chain fatty acid as effective ingredients. Specifically, the present invention relates to a medium-chain fatty acid and / or an uncoupling protein (hereinafter referred to as "UCP") that has a special effect on promoting growth and preventing obesity by consuming surplus energy and generating heat. Body temperature raising agent, oil composition, beverage and food containing glycerin fatty acid ester of medium-chain fatty acid. Background technique [0002] Ways to warm up in cold storage in summer and in cold winter include methods such as massaging hands and feet, promoting blood circulation with commercially available thermal insulation materials and heat preservation agents, or taking heat into the body through hot drinks and food. And developed a massage agent for this purpose. But using these methods, al...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23D7/005A23D9/00A23D9/007A23L1/30A23L2/38A23L27/60A61K31/165A61K31/20A61K31/23A61K31/231A61K31/355A61K31/426A61K31/4415A61K31/661A61K33/06A61K33/26A61K33/30A61K45/06A61P3/04A61P3/06A61P3/10A61P9/00A61P43/00
CPCA23D9/00A23D9/007A23V2002/00A61K31/20A61K31/23A61K31/231A61K31/355A61K31/426A61K31/4415A61P3/04A61P3/06A61P3/10A61P9/00A61P43/00A61K2300/00A23V2250/1878A23V2250/042A23V2250/51086A23V2250/5118A61K31/165
Inventor 篠原久实野口修浅见文江嵨田初美乾利之
Owner THE NISSHIN OILLIO GRP LTD
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