Fleabane and earthworm dripping pill and its preparing method

A technology of Dilong and Dengzhan, which is applied in the field of Dengzhan Dilong dripping pills and its preparation, can solve the problems of long dissolution time, unfavorable improvement of patients' ability to seek medical treatment, and low dissolution rate, so as to avoid gastrointestinal irritation symptoms and improve Bioavailability, Dissolution and Absorption Accelerated Effects

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0009] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] Now with several groups of specific examples, the preparation method of the scutellaria breviscens dripping pills of the present invention will be further described.

[0033] Group 1: Tests with a single matrix

[0034] 1. According to the preparation method given in [Appendix], the dry powder of the extract containing two active ingredients of traditional Chinese medicines, Dilong and Erigeron breviscapus, was first prepared for use;

[0035] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0036] 3. Proportion: take g or kg as the unit, by weight parts, drug dry powder: matrix = 1:1~1:9;

[0037] 4. Then prepare according to the process of [Preparation Method] 4-7, and various specifications of Dengzhan Dilong dripping pills can be prepared.

[0038] [test results]

[0039]Expe...

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PUM

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Abstract

The fleabane-earthworm dripping pill is a kind of oral medicine composition preparation with the functions of promoting blood circulation and dredging meridian passage for treating ischemic apoplexy, etc. It is developed on the basis of available fleabane-earthworm capsule and has high bioavailability, fast medicine release, fast acting, high effective component content, low cost and less toxic side effect, and the production process has no pollution. The fleabane-earthworm dripping pill is prepared with fleabane and earthworm as Chinese medicine material and matrix carrier.

Description

technical field [0001] The invention relates to a pharmaceutical composition with the function of promoting blood circulation and dredging collaterals, and is used for treating ischemic stroke and other diseases caused by blood stasis and obstructing collaterals, in particular to a traditional Chinese medicine prescription Dengzhan Dilong Capsules, which is formulated through formulation reformation. A medicine composition oral drop pill preparation. Background technique [0002] Dengzhan Dilong Capsules, prepared according to the formula and preparation process given in the national drug standard WS-10424 (ZD-0424)-2002, is a kind of capsule that has the effect of promoting blood circulation and dredging collaterals, and is used to treat deficiency caused by blood stasis and obstruction of collaterals. Oral Chinese medicine preparations for symptoms such as hemorrhagic apoplexy have been clinically verified to have stable quality and definite curative effect. The following...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K35/62A61P9/10
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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