Calculus bovis detoxifying dropping pill, and its preparing method
The technology of bezoar and rhubarb is applied in the field of oral preparations of pharmaceutical compositions, which can solve problems such as being unfavorable to improve the ability of patients to seek medical treatment, bioavailability of liver and intestine first-pass effect, physical harm to staff, etc., so as to improve bioavailability, drug safety, The effect of low labor intensity
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[0034] The preparation method of Niuhuangjiedu dripping pills of the present invention will be further described with several groups of specific examples.
[0035] [Group 1: Trials with a single substrate]
[0036] 1. Preparation of medicinal extracts: According to the [Appendix], first prepare the dry powder of extracts containing active ingredients of 8 traditional Chinese medicines, such as bezoar, realgar, gypsum, rhubarb, scutellaria, platycodon, borneol, and licorice;
[0037] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;
[0038] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0039] 4. According to the process given in [Preparation Method] 4-7, Niuhuangjiedu dripping pills of different specifications c...
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