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Calculus bovis detoxifying dropping pill, and its preparing method

The technology of bezoar and rhubarb is applied in the field of oral preparations of pharmaceutical compositions, which can solve problems such as being unfavorable to improve the ability of patients to seek medical treatment, bioavailability of liver and intestine first-pass effect, physical harm to staff, etc., so as to improve bioavailability, drug safety, The effect of low labor intensity

Active Publication Date: 2005-12-21
JIANGXI JIMINKEXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0034] The preparation method of Niuhuangjiedu dripping pills of the present invention will be further described with several groups of specific examples.

[0035] [Group 1: Trials with a single substrate]

[0036] 1. Preparation of medicinal extracts: According to the [Appendix], first prepare the dry powder of extracts containing active ingredients of 8 traditional Chinese medicines, such as bezoar, realgar, gypsum, rhubarb, scutellaria, platycodon, borneol, and licorice;

[0037] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0038] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0039] 4. According to the process given in [Preparation Method] 4-7, Niuhuangjiedu dripping pills of different specifications c...

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PUM

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Abstract

The present invention discloses a Chinese medicine composition Neuhuang Jiedu dripping pill preparation with effects of clearing away heat and removing toxic material for curing the diseases of sore swollen throat, gingivitis, mouth and tongue sores and sore and swollen eyes due to pathogenic interior fire with obvious therapeutic effect. Said Chinese medicine dripping pill preparation is made up by using 8 Chinese medicinal materials of bovine bezoar, realgar, gypsum, rhubarb, scutellaria root and others and adopting a certain preparation process.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has heat-clearing and detoxifying effect, and is used for the treatment of illnesses such as fiery heat, sore throat, gingival swelling and pain, aphtha of the mouth and tongue, red eyes and swelling and pain. An oral preparation of a pharmaceutical composition prepared from active ingredient extracts of 8 traditional Chinese medicines such as rhubarb, scutellaria baicalensis, bellflower, borneol, licorice, etc. as raw materials. Background technique [0002] According to the preparation method given under Niuhuangjiedu pills on page 386 of the Chinese Pharmacopoeia 2005 edition, Niuhuangjiedu pills are a kind of medicine that has the effect of clearing away heat and detoxifying. , an oral preparation for the treatment of conjunctival congestion, swelling and pain, etc., has been clinically verified and has definite curative effects. It is a commonly used drug for clinical and family ...

Claims

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Application Information

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Inventor 曲韵智
Owner JIANGXI JIMINKEXIN PHARMA
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