Blood treatment device and method with selective solute extraction

A technology of blood and treatment unit, applied in the field of devices and methods for extracorporeal treatment of blood by selectively extracting solutes

A technology of blood and treatment unit, applied in the field of devices and methods for extracorporeal treatment of blood by selectively extracting solutes

CN1761494AActive Publication Date: 2006-04-19GAMBRO LUNDIA AB
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  • Blood treatment device and method with selective solute extraction
  • Blood treatment device and method with selective solute extraction
  • Blood treatment device and method with selective solute extraction

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Embodiment Construction

[0044]Figure 4 shows in a schematic way the principle of the invention: blood flows through an input line, arrives in the exchanger and exits the exchanger through an output line, together with the treatment of the first filtrate by the treatment unit and the dilution before use leaving the treatment unit The fluid is injected into the arterial line.

[0045] We can define this concept as a "cascade" of filtration steps in which the final filtrate is reinjected by dilution before use: specifically: a first filtrate is filtered a second time, and then the second filtrate is injected at the inlet of the first filter , or rather in "pre-dilution".

[0046] Figure 5 shows an extracorporeal blood treatment device according to the invention comprising an exchanger 1 comprising a first inlet 2 for treated blood, a first liquid outlet 4 and a second liquid outlet 5 an input line or arterial line 10 for treated blood connected to the first inlet 2 of the exchanger 1 ; a blood output l...

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Abstract

The object of the present invention is the filtration of blood in order to selectively separate and extract molecules of a given size via extracorporeal systems for separating substances. The invention thus concerns an extracorporeal blood treatment device including: one or more exchangers (1) comprising a first inlet (2) for the blood to be treated, a first fluid outlet (4) and a second fluid outlet (5), an inlet line (10) for the blood to be treated, connected to the first inlet (2) of the exchanger (1), a blood outlet line (or venous line) (11) coupled to the first outlet (4) of the exchanger (1), one or more treatment units (21) comprising at least a first fluid inlet (22) and at least a first fluid outlet (24), wherein the second outlet (5) of the exchanger (1) is in fluid communication with the first inlet (22) of the treatment unit (21), the invention being characterised in that the first outlet (24) of the treatment unit (21) is in fluid communication with the inlet line (10).

Description

technical field [0001] The object of the present invention is a device and a method for the treatment of blood by selective extraction of solutes. [0002] The object of this patent application is to filter blood to selectively separate and extract dissolved substances of selected molecular sizes by means of an extracorporeal system designed for the separation of substances. [0003] Such systems are used to treat blood containing solutes of different molecular weights. Examples of such substances are urea with a molecular weight of 60 Daltons, phosphates (96-97 Daltons), creatinine (113 Daltons), vitamin B 12 (1355 Daltons), inulin (5200 Daltons), β2-microglobulin (12000 Daltons) and albumin (58000 Daltons). [0004] Hereinafter, "small molecules" are molecules with a molecular weight below about 2000 Daltons, "medium molecules" are those with a molecular weight between 2000 and 50000 Daltons, and "large molecules" are those with a molecular weight greater than 50000 Dalton...

Claims

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Application Information

Patent Timeline
19 Apr 2006
Publication
CN1761494A
IPC
A61M1/34; A61M1/16; A61L2/00; A61M1/36
CPC
A61M2001/3479; A61M1/1696; A61M1/3496; A61M2001/3482; A61M2001/3434; A61M2001/3437; A61M1/3681; A61L2/0011
Inventors
J·舍瓦莱; G·梅西耶