Medicine for treating osteoporosis and its preparing method and use

A technology for osteoporosis and drugs, which is applied in the field of traditional Chinese medicine, can solve the problems of unavailable active ingredients, many side effects, and poor efficacy of drugs, and achieve the effect of being suitable for industrialized large-scale production, easy process steps, and enhanced curative effect

Active Publication Date: 2006-06-07
GUOYAOJITUAN TONGJITANG (GUIZHOU) PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as estrogen, calcitonin, calcium preparations, active vitamin D, etc., but the long-term use of the above drugs can cause complications; or the price is expensive; or the curative effect is not exact; many side effects are not ideal drugs for the treatment of osteoporosis
Also disclose many relevant medicines for the treatment of osteoporosis in the patent literature, for example, disclose a kind of with Epimedium 78-80%, Dipsacus chuanxiong 10-15%, Psoralen 3-5% in the Chinese patent application CN1200279A , Shengdi 3-5%, Salvia miltiorrhiza 3-5%, Mao Zhimu 3-5% are raw materials, and the medicine for preventing and treating osteoporosis made according to the conventional preparation method of boiled in water, the disadvantage of this application is that it adopts It is a preparation method of conventional water decoction, in which the active ingredients of epimedium and psoraleae which play a major role cannot be obtained, thereby directly affecting the effect of the final drug, and the drug effect of the drug is relatively poor in practical applications

Method used

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  • Medicine for treating osteoporosis and its preparing method and use
  • Medicine for treating osteoporosis and its preparing method and use
  • Medicine for treating osteoporosis and its preparing method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0363] Epimedium 1500g Dipsac 800g Salvia 100g

[0364] Anemarrhena vulgaris 100g Psoralen 100g Rehmannia glutinosa 100g

[0365] Weigh each flavour according to the prescription, smash the salvia, dipsacus and psoralen, and pass through a 200-mesh sieve to make a very fine powder; crush the remaining raw materials, add water to extract 3 times, add 30 times water each time, and extract 3 and 2 in turn , 1 hour, filter or centrifuge to obtain the water extract; concentrate the above water extract to a thick paste with a relative density of 1.35-1.38 (30 degrees); add 3 times the dextrin and lactose; then add the above Danshen, continued The psoralen powder is broken and mixed, granules are made, and dried to obtain the capsules of the present application.

Embodiment 2

[0367] Epimedium 1167g Dipsacus 167g Salvia 83g

[0368] Zhimu 83g Psoralen 83g Rehmannia glutinosa 83g

[0369] Weigh each flavor according to the prescription, crush the salvia, sieved through 80 mesh sieve, and make fine powder; crush the remaining raw materials, add water for extraction 2 times, add 20 times water each time, extract 3 hours each time, filter or centrifuge to obtain water Extraction; Concentrate the above water extract to a clear ointment with a relative density of 1.20 (50 degrees); then add the above Danshen powder, mix uniformly, make granules, and dry to obtain the tablet of the application.

Embodiment 3

[0371] Epimedium 1200g Dipsacus 200g Salvia 500g

[0372] Anemarrhena 500g Psoralen 500g Rehmannia glutinosa 500g

[0373] Weigh each flavor according to the prescription, crush the salvia, sieved through a 100-mesh sieve, and make a very fine powder; crush the remaining raw materials, add water to extract 3 times, add water 20 times each time, extract 2 hours each time, filter or centrifuge, and get water Extraction; Concentrate the above-mentioned aqueous extract; Dry and pulverize into a 100-mesh ultra-fine powder; Add 2 times the amount of dextrin and lactose;

[0374] Then add the above-mentioned Danshen powder, mix well, granulate, dry, and sizing to obtain the granule of the present application.

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Abstract

The patent application relates to a kind of osteoporosis treating medicine and its preparation process as well as its new use in treating fracture, osteoarthritis, osteonecrosis and climacteric syndrome. The medicine is prepared with epimedium, teasel root, red sage, anemarrhena rhizome, malaytea scurfpea fruit and rehmannia root. Clinical and animal experiment research shows that the medicine has higher curative effect and no side effect compared with other medicine for treating osteoporosis, and may be taken regularly.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating osteoporosis, and a preparation method and application thereof. Background technique [0002] Osteoporosis is mainly divided into two categories: primary osteoporosis and secondary osteoporosis. The causes of its pathogenesis are very complicated. However, from the perspective of traditional Chinese medicine, osteoporosis belongs to the scope of "Kidney Deficiency Osteoporosis". The theory of traditional Chinese medicine believes that: "people are born by the qi of heaven and earth", "the innate essence is hidden in the kidney, and the kidney is the innate foundation", "the kidney governs the bones to produce essence, reproduces, resuscitates the ears and the second yin", and "the kidney is in The body unites the bones and the main bone produces marrow. "The kidneys and qi feet produce the marrow and the bones are nourished." The kidney in ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P19/10
Inventor 周宁
Owner GUOYAOJITUAN TONGJITANG (GUIZHOU) PHARMA CO LTD
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