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Plaster for relieving asthma and stopping cough and its preparation method

A cataplasm and anti-asthma technology, which is applied in the field of traditional Chinese medicine patches and its preparation, can solve problems such as allergies, skin rashes, and small drug loads, and achieve the effect of long-acting drug release, moderate elasticity, and strong sustained-release effect

Active Publication Date: 2006-10-11
张高红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional plasters (soft plasters, black plasters) are all based on fat-soluble materials, which have serious defects in application: small drug load, poor transdermal performance, allergies, rashes, hair sticking, clothing contamination, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: preparation of cataplasm matrix

[0031] (1) Weighing: gelatin 0.450kg, polyvinyl alcohol 0.380kg, sodium carboxymethylcellulose 0.205kg, castor oil 0.260kg, sodium polyacrylate 0.122kg, Tween-80 0.159kg, sorbic acid 0.009kg, kaolin 0.460 kg, glycerin 0.660kg, tartaric acid 0.760kg, sorbitol 0.285kg, stomach-soluble film-coating powder 2.050kg, distilled water 4.200kg.

[0032] (2) Gelatin, polyvinyl alcohol and sodium carboxymethyl cellulose were formulated into sols respectively.

[0033] (3) Then add them to the container in the order of weighing, set the initial stirring speed at 100rpm., then increase the speed of 60-80rpm. for each material added, and stir for 6-9min. After the feeding is completed, the stirring speed is raised to 1000-1200 rpm., and the stirring is continued for 8-12 minutes to obtain the cataplasm matrix of the present invention.

Embodiment 2

[0034] Embodiment 2: the preparation of medicament in the antiasthma and antitussive plaster cataplasm

[0035] 1. Preparation of antiasthma and cough patch cataplasm extract:

[0036](1) Weighing of traditional Chinese medicine: 2000g of ephedra, 2000g of white mustard seed, 500g of kansui, 1000g of auspicious grass, 1500g of perilla seed, 1000g of asarum, 500g of pedicel seed, and 1000g of Aodi tea.

[0037] (2) Extraction of extract, after weighing the above-mentioned medicinal materials, put them into a multi-energy extraction tank, add 9.5 × 8kg of 65-70% ethanol for the first time and impregnate for 6-8 hours, then adopt the reflux extraction method, and reflux extraction 6 hour, add 9.5 × 6kg 50-60% ethanol for the second time to reflux extraction for 2 hours, combine the filtrate and concentrate to a clear paste with a relative density of 1.20 (60°C), the recovered ethanol is stored for later use, and finally the extract is used in 200-400 mesh After the strainer is f...

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PUM

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Abstract

Disclosed is a cataplasma for cough-relieving and its preparing process, which is the formulation of extracts comprising Chinese ephedra 1.8-2.2, white mustard seed 1.8-2.2, kansui root 0.4-0.6, perilla fruit 1.4-1.6, asaryl 0.9-1.1, thorny elaeagnus fruit 0.4-0.5, and Japanese ardisia 0.9-1.1.

Description

technical field [0001] The patent of the present invention relates to a traditional Chinese medicine patch and a preparation method thereof, in particular to a traditional Chinese medicine patch which is effective in treating asthma and cough, and a preparation method thereof. Background technique [0002] As we all know, plaster refers to a class of sheet-shaped external preparations made of medicinal material extracts or chemical drugs and suitable substrates for skin sticking and can produce local or systemic effects. These include rubber plasters, poultices, and patches. [0003] Traditional plasters (soft plasters, black plasters) are all based on fat-soluble materials, which have serious defects in application: small drug load, poor transdermal performance, allergies, rashes, adhesion of fine hair, contamination of clothing, etc. [0004] In the late 1970s, Japan developed a water-soluble matrix plaster for opening up the western market. This type of plaster has been ...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/70A61P11/06A61P11/14
Inventor 张高红
Owner 张高红
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