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Compounded preparation of Radix As tragali seu Hedy ari extract and mushroom polysaccharide and preparing method

A technology of astragalus extract and lentinan, which is applied to medical preparations containing active ingredients, drug combinations, plant/algae/fungus/moss ingredients, etc., can solve the problems of high import price and the like, and achieve the effect of convenient use

Inactive Publication Date: 2006-10-25
上海慈瑞医药科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But imports are expensive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take 2 grams of lentinan for injection, put it into a container and dissolve it with 700ml of 0.6mol / L sodium hydroxide aqueous solution at room temperature, add 400ml of ordinary 20% mannitol injection after dissolving, stir well, add astragalus extract containing 50% astragalus polysaccharide 4 grams of the substance, after dissolving, adjust the pH to 7-9 with dilute acid solution, filter, concentrate under reduced pressure to 1000ml, filter aseptically, sterilize, measure the content, sub-package, 1ml / bottle, cool and dry, and seal to obtain the compound Astragali- Lentinan freeze-dried powder injection.

Embodiment 2

[0028] Take 1 gram of lentinan for injection, put it into a container and dissolve it with 700ml of 0.2mol / L sodium hydroxide aqueous solution at room temperature. Adjust the pH to 7-9, filter, add water for injection to 1200ml, filter aseptically, sterilize, divide into appropriate containers, seal, and obtain the compound lentinan water injection.

Embodiment 3

[0030] Take 0.1 g of lentinan for injection, put it into a container and dissolve it at room temperature with 923 ml of 1mol / L sodium hydroxide aqueous solution. After the dissolution is complete, add 0.2 g of astragalus extract containing 30% astragaloside IV and 70% astragalus polysaccharide. Extract 0.3 g, add 923ml of 1mol / L hydrochloric acid solution after dissolving, adjust pH to 7-9 with sodium hydroxide solution or hydrochloric acid solution of the same concentration, filter, add water for injection to 6000ml, sterile filter, sterilize, divide Fill it into a suitable container to get the compound astragalus-lentinan infusion.

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PUM

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Abstract

The present invention relates to a compound preparation formed from astragalus extract and lentinan and its preparation method. Its preparation method includes the following steps: dissolving lentinan in sodium hydroxide solution at room temperature, adding mannitol injection in dissolved solution, uniformly stirring them, adding astragalus extract, using acid to regulate pH value, aseptic filtering so as to obtain compound astragalus and lentinan freeze-dried powder injection, water injection, transfusion agent and capsule preparation. It can be used for preventing and curing the diseases of tumor, viral myocarditis, viral hepatitis, immunologic hypofunction, chronic nephritis and chronic renal failure and chronic bronchitis, etc.

Description

technical field [0001] The invention relates to a compound preparation composed of astragalus extract and lentinan and a preparation method thereof. The compound preparation has an immune-enhancing effect, and can be used in the prevention and treatment of tumors, the rectification of the infirm, and the treatment of viral myocarditis, viral hepatitis, The invention has therapeutic effects on low immune function, chronic nephritis, renal failure, chronic bronchitis, etc., and belongs to the technical field of pharmaceutical preparations. Background technique [0002] With the changes in human living environment, living standards and lifestyles and the advancement of medicine, the spectrum of human diseases has undergone significant changes, general infectious diseases have been gradually controlled, and malignant tumors have become increasingly common and seriously threaten human life and quality of life. one of the main diseases. According to the statistics of the World He...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K9/08A61K9/14A61K9/19A61K9/20A61K9/48A61P13/12A61P31/12A61P37/04
Inventor 金幸汤磊陈林祥朱益峰
Owner 上海慈瑞医药科技股份有限公司
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