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Medicine for treating adiposis hepatica, and its prepn. method

A fatty liver and drug technology, applied in the field of drugs for the treatment of fatty liver, can solve the problems of uncertain curative effect and non-specificity

Inactive Publication Date: 2007-02-14
JIANGSU SHENHUA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, in the treatment of Chinese patent medicines, the curative effect is mostly uncertain, and most of them are not specific, and there is no new traditional Chinese medicine drug with certain curative effect and specially for the treatment of this disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Weigh 1000g of Gynostemma pentaphyllum, 400g of Salvia miltiorrhiza, 1000g of Polygonum cuspidatum, 300g of dried lotus leaves, and 600g of capillary wormwood, add water to decoct three times, and add 6 times the amount of water for the first time. After soaking for 30 minutes, extract for 1 hour, filter, and extract the filter residue with 3 times and 3 times of water for 1 hour respectively, combine all the filtrates, concentrate under reduced pressure to an extract with a specific gravity of 1.23-1.25 (50°C), and stir Slowly add 2 times the amount of 95% ethanol under low pressure, separate the supernatant, reclaim the ethanol and concentrate under reduced pressure to obtain an extract with a relative density of 1.20-1.22# (70-80°C), dry under reduced pressure at 70°C, dry the extract with Soybean oil containing an appropriate amount of beeswax is superfinely pulverized, made into a paste, pressed into soft capsules, and granulated to obtain the product.

Embodiment 2

[0084] Weigh 1500g of Gynostemma pentaphyllum, 500g of Salvia miltiorrhiza, 1000g of Polygonum cuspidatum, 300g of dried lotus leaf, and 600g of capillary root, add water to decoct three times, add 6 times the amount of water for the first time, soak for 30 minutes, extract for 1 hour, filter, and use 3 times the filter residue in turn , 3 times the amount of water and extract each for 1 hour, combine all the filtrates, concentrate under reduced pressure to an extract whose specific gravity is 1.23-1.25 (50°C), slowly add 2 times the amount of 95% ethanol under stirring, separate the supernatant, and recover Concentrate ethanol under reduced pressure into an extract with a relative density of 1.20-1.22# (70-80°C), dry under reduced pressure at 75°C, and superfinely pulverize the dry extract with soybean oil containing an appropriate amount of beeswax to make a paste and press Made into soft capsules, granulated, and obtained.

Embodiment 3

[0086] Weigh 1500g of Jiaogulan, 500g of Danshen, 1500g of Polygonum cuspidatum, 400g of dried lotus leaf, and 700g of capillary, add water to decoct three times, add 6 times the amount of water for the first time, soak for 30 minutes, extract for 1.5 hours, filter, and use 3 times the filter residue in turn , 3 times the amount of water and extract each for 1-5 hours, combine all the filtrates, concentrate under reduced pressure to an extract whose specific gravity is 1.23-1.25 (50°C), slowly add 2 times the amount of 95% ethanol under stirring, and take the supernatant , recovering ethanol and concentrating under reduced pressure into an extract with a relative density of 1.20-1.22 (70-80°C), drying under reduced pressure at 75°C, and superfinely pulverizing the dry extract with soybean oil containing an appropriate amount of beeswax to make a paste, Compressed into soft capsules and granulated to obtain the final product.

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PUM

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Abstract

A Chinese medicine for treating fatty liver is prepared from 5 Chinese-medicinal materials including gynostemma pentaphyllum, red sage root, dried lotus leaf, oriental wormwood, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a medicine for treating fatty liver and a preparation method thereof. Background technique [0002] Fatty liver is a fatty change in the liver caused by a variety of reasons. Its incidence is closely related to age, gender, blood lipids, high blood pressure, obesity, etc. Alcoholism, high-fat protein diet, extra meals before going to bed, and excessive sleep are the main causes of fatty liver disease. major risk factors for the liver. Due to changes in people's living conditions and lifestyles, alcoholism, overnutrition obesity, diabetes and drug-induced damage have become important causes of fatty liver. The prevalence of fatty liver and related diseases has increased significantly. [0003] Fatty liver is often treated with lipid-lowering drugs. Since the 1980s, blood lipid-lowering drugs have been constantly updated, but clinical practice has found that most chemically synthesized blood-lipid-lowering drugs have unsatisfa...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61K9/48A61P1/16
Inventor 季光安红梅郑培永
Owner JIANGSU SHENHUA PHARMA
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