Medicinal composition of douricine, tinosporae or its extract
A composition, the technology of Beidougen, applied in the field of medicine, achieves the effect of inhibiting writhing reaction, high content, and reducing mortality
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Embodiment 1
[0126] Example 1 Preparation, Identification and Content Determination of Northern Bean Root Extract
[0127] Preparation of Bean Root Extract A
[0128] Take 10 kg of bean root, crush it into coarse powder, add 8 times the amount of sulfuric acid aqueous solution (pH1~2), warm soak (55~60°C) twice, each time for 24 hours, filter, combine the filtrates, let stand, After the precipitation is complete, take the supernatant and add carbonic acid to adjust the pH value to 9, let it stand until the precipitation is complete, discard the supernatant, take the precipitate and filter it, wash it with a small amount of water until it is neutral, dry it at 50-60°C, add an appropriate amount of chloroform to dissolve it , shake and extract three times with aqueous sodium hydroxide solution, 1 times the amount each time, discard the extract, concentrate and dry the chloroform layer to obtain that.
[0129] Six batches of bean root extracts were prepared respectively, and the yields are s...
Embodiment 2
[0141] Example 2 Preparation, Identification and Content Determination of Lavender Extract
[0142] Preparation of Lavender Extract
[0143] Take 10kg of Lavender, crush it into a coarse powder, reflux and extract with 70% ethanol twice, each time for 2 hours, filter, combine the filtrate, recover the ethanol until it has no alcohol smell, add water to adjust the total amount of the concentrated solution to 1000ml, add concentrated hydrochloric acid to adjust When the pH value reaches 1-2, stir and filter, the filtrate passes through the treated strong acid cation exchange resin, washes with water until the eluent is neutral, dries the resin, and adds an appropriate amount of concentrated ammonia test solution to make it wet. Put it in a Soxhlet extractor, add ethanol to reflux and extract for 5 hours, recover ethanol from the ethanol solution, and dry it in vacuum to obtain the product.
[0144] Prepare six batches of Lamicarina extracts, and the yields are shown in Table 2-...
Embodiment 3
[0158] Embodiment 3 Preparation of the pharmaceutical composition injection of the present invention
[0159] 1. Prescription:
[0160] Prescription 1
[0161] North bean root extract A 257g (equivalent to 24kg of raw medicinal materials)
[0162] Golden fruit olive extract 10g (equivalent to 1kg of raw medicinal materials)
[0163] Polysorbate 80 100g
[0164] Add water for injection to 5000ml
[0165] A total of 1000 sticks were prepared
[0166]Prescription 2
[0167] North bean root extract A 257g (equivalent to 24kg of raw medicinal materials)
[0168] Golden fruit olive extract 29g (equivalent to 3kg of raw medicinal materials)
[0169] Polysorbate 80 100g
[0170] Add water for injection to 5000ml
[0171] A total of 1000 sticks were prepared
[0172] Prescription 3
[0173] North bean root extract A 257g (equivalent to 24kg of raw medicinal materials)
[0174] Golden fruit olive extract 58g (equiva...
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