Method for preparing medicinal lining for preventing and treating mammary glands hyperplasia and application thereof

A technology for mammary gland hyperplasia and fabrics, applied in the application, pharmaceutical formulations, drug devices and other directions, can solve problems such as affecting the appearance and not meeting the aesthetic needs of modern people, and achieve the effect of drug safety, avoiding first-pass effect and reducing pain.

Active Publication Date: 2007-04-25
ZHEJIANG LANGSHA UNDERWEAR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] c. Affects the appearance and does not meet the aesthetic needs of modern people

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A medical fabric for preventing and treating mammary gland hyperplasia is fixed with drug microcapsules using the medicine for preventing and treating mammary gland hyperplasia as the capsule core material and drug transdermal absorbent microcapsules using the medicine for preventing and treating mammary gland hyperplasia as the capsule core material.

[0032] 1. Preparation of microcapsules

[0033] (1) Preparation of drug microcapsules

[0034] The drug microcapsules are prepared by a single coacervation method, and the drug used for preventing and treating mammary gland hyperplasia is tamoxifen.

[0035] Weigh 2.0 g of tamoxifen, suspend it in 40 ml of 5% gelatin solution, add 10% acetic acid to pH 3.6, and stir in a water bath at 50°C. Add 30% sodium sulfate solution dropwise, and observe under the microscope that after coagulation into capsules, pour it into the diluent that is being stirred immediately. After the coagulation capsules settle, pour off the supernat...

Embodiment 2

[0050] A medical fabric for preventing and treating mammary gland hyperplasia is fixed with drug microcapsules using the medicine for preventing and treating mammary gland hyperplasia as the capsule core material and drug transdermal absorbent microcapsules using the medicine for preventing and treating mammary gland hyperplasia as the capsule core material.

[0051] 1. Preparation of microcapsules

[0052] (1) Preparation of drug microcapsules

[0053] The drug microcapsule is prepared by chemical emulsion polymerization, and the drug used for preventing and treating mammary gland hyperplasia is isoflavone.

[0054]Weigh 1.5g of isoflavones, 1g of methyl methacrylate, 0.5g of acrylonitrile, and 0.3g of acrylic acid, and mix them uniformly to form an oil phase. Weigh 4g of water (an appropriate excess of water to make up for the loss), 0.2g of emulsifier MS-1, and 0.08g of Pingping into the emulsifier, start the motor, and start stirring. Put the above oil phase into the pre...

Embodiment 3

[0069] A medical fabric for preventing and treating mammary gland hyperplasia is fixed with drug microcapsules using the medicine for preventing and treating mammary gland hyperplasia as the capsule core material and drug transdermal absorbent microcapsules using the medicine for preventing and treating mammary gland hyperplasia as the capsule core material.

[0070] 1. Preparation of microcapsules

[0071] (1) Preparation of drug microcapsules

[0072] The drug microcapsules are prepared by radiation emulsion polymerization, and the drug used for preventing and treating mammary gland hyperplasia is bromocriptine.

[0073] Weigh 1.5g bromocriptine, 1.5g styrene, 1.1g acrylonitrile, 0.5g butyl acrylate into a container and mix well. Accurately weigh 0.2g of emulsifier 05-1, 0.2g of Pingpingjia, and 5.5g of water (an appropriate excess of water to supplement the loss) and add them to the above container. Put the stirrer device with a homogenizer into the above container, start...

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Abstract

The invention relates to a method for preparing the drug material used to treat mammary gland hyperplasia. Wherein, it fixes the drug micro capsule whose corn is the said treatment drug and the drug transparent absorber micro capsule whose corn is the drug transparent absorber, while their weight ratio is 100-10:1-10. The preparation comprises that 1, preparing the drug micro capsule and the drug transparent absorber micro capsule; 2, mixing them at 100-10:1-10 into the micro capsule.

Description

technical field [0001] The invention relates to a preparation method and application of a medicinal fabric for preventing and treating mammary gland hyperplasia, in particular to a medicinal fabric for preventing and treating mammary gland hyperplasia, its preparation method and application. Background technique [0002] Mammary gland hyperplasia is the most common breast disease, and its incidence rate accounts for the first place in breast diseases. For the treatment of mammary gland hyperplasia, traditional Chinese medicine generally takes orally or externally applies some traditional Chinese medicines that soothe the liver, regulate qi, activate blood and remove blood stasis; Western medicine uses hormone drugs or surgical treatment. The effect of traditional Chinese medicine treatment of this disease is better, but the oral treatment of traditional Chinese medicine is loaded down with trivial details because of boiling medicine, and the medication time is long, and the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A41B17/00D06B1/02D06B3/18A61M37/00A61K9/50A61K31/352A61K31/138A61K31/4985A61K31/58A61K47/22A61K47/10A61K47/12A61P15/14
Inventor 朱利民樊在霞马宗会
Owner ZHEJIANG LANGSHA UNDERWEAR
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