CANINE IgG NUCLEIC ACID MOLECULES

a technology of canine igg and nucleic acid molecules, which is applied in the field of canine igg and canine interleuken13 receptor proteins, fusion proteins, etc., can solve the problem of difficult to separate the roles of these cytokines
US20080287665A1Inactive Publication Date: 2008-11-20MCCALL CATHERINE A +1
15 Cites 6 Cited by

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
MCCALL CATHERINE A
Publication Date
2008-11-20
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and / or canine IL-13R. In particular, the present invention discloses nucleic acid molecules encoding canine IgG, including species-specific regions of the heavy chain of canine IgG, and canine IL-13R alpha chain (IL-13Rα) proteins, particularly canine interleuken receptor alpha 1 (IL-13Rα1) and canine interleuken receptor alpha 2 (IL-13Rα2) proteins. Also included are canine IgG and IL-13Rα proteins, antibodies having selectivity for such proteins, inhibitors of such proteins and / or nucleic acid molecules, cells transformed with said nucleic acid molecules, assays employing such cells, nucleic acids molecules, proteins, antibodies and / or inhibitors, and therapeutic compositions comprising said nucleic acids molecules, proteins, antibodies and / or inhibitors. Also included are kits containing said molecules or chimera thereof, including their use to evaluate and regulate an immune response in an animal.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a divisional of co-pending U.S. patent application Ser. No. 10 / 753,159, filed Jan. 7, 2004, entitled “CANINE IL-13 RECEPTOR ALPHA-1 SUBUNIT NUCLEIC ACID MOLECULES”; which is a divisional of U.S. patent application Ser. No. 09 / 828,995, filed Apr. 9, 2001, and issued as U.S. Pat. No. 6,703,360, entitled “COMPOSITIONS AND METHODS RELATED TO CANINE IgG AND CANINE IL-13 RECEPTORS”; which claims priority to U.S. Provisional Application Ser. No. 60 / 195,874, filed Apr. 7, 2000, entitled “CANINE IMMUNOGLOBULIN G MOLECULES AND RELATED METHODS”; and U.S. Provisional Application Ser. No. 60 / 195,659, filed Apr. 7, 2000, entitled “CANINE IL-13 RECEPTORS, PROTEINS, NUCLEIC ACIDS AND USES THEREOF”; all of which are incorporated by reference herein.FIELD OF THE INVENTION

[0002] The present invention relates to novel canine proteins, and more particularly to canine IgG and canine interleuken-13 receptor proteins, fusion proteins, nucleic ...

Claims

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