Compositions and methods for minimizing and/or reducing the appearance of defects around eyes

a technology of defects and compositions, applied in the field of compositions and methods for minimizing and/or reducing can solve the problems of skin sensitive or intolerant, skin that is easy to be dehydrated and vulnerable to external aggression, and skin that is sensitive to external aggression, etc., to reduce the appearance of defects around eyes.

Inactive Publication Date: 2009-10-22
LOREAL SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0015]The present invention further relates to methods for reducing and / or minimizing the appearance of defects around eyes such as, for example, dark circles, bags and / or puffiness, comprising topically applying to the skin around eyes a composition comprising at least one xanthine compound. Preferably, the compositions further comprise at least one agent which acts on capillary circulation and / or at least one natural moisturizing agent. Also preferably, application of the composition to the skin around eyes occurs without contacting the composition with human hands and / or fingers prior to application.

Problems solved by technology

Thus, it is easily dehydrated and vulnerable to external aggressions, meaning that such skin requires particular care.
Moreover, the skin of the eye contour is very reactive due to its richness in inflammatory cells (mast cells), meaning that such skin can be sensitive or intolerant leading, perhaps, to allergic reactions.
Furthermore, the skin of the eye contour can be particularly sensitive to solar radiation.
Excessive exposure without protection can lead to redness, sensitivity, or even swelling via microcirculation disorders.
The formation of dark circles often occurs as a result of slowing blood microcirculation, especially at night, which leads to an accumulation of blood pigments in the conjunctive tissue.
Furthermore, the lymphatic system, also slowed during the night, leads to swelling of this skin.
Defects around eyes such as dark circles and swelling have always been considered to be unattractive, and it has always been a goal to mask them or even eliminate them.

Method used

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  • Compositions and methods for minimizing and/or reducing the appearance of defects around eyes

Examples

Experimental program
Comparison scheme
Effect test

example 1

Composition

[0057]

BUTYLENE GLYCOL5XANTHAN GUM0.4CAPRYLYL GLYCOL0.3GUANOSINE0.01DISODIUM EDTA0.2BIOSACCHARIDE GUM-15POLYACRYLAMIDE (and) C13-140.4ISOPARAFFIN (and) LAURETH-7HYDROXYPROLINE0.3GLYCERIN3CAFFEINE0.5ESCIN0.05WATER83.87PANTHENOL0.5SODIUM HYALURONATE0.02PRESERVATIVE AGENTS0.45Total:100 indicates data missing or illegible when filed

example 2

Application of the Composition of Example 1 to the Contour of the Eye—Moisturizing Effect

[0058]The composition of example 1 was placed into a roll-on dispenser. 24 subjects applied the composition of example 1 to the contour of their eyes using the dispenser a single time. The skin of the subjects thus-treated 4 hours after application as well as 8 hours after application was compared to the skin prior to treatment. The subjects' skin was evaluated using a corneometer which estimated the water content in stratum corneum of the skin from electric capacitance—the higher the water content, the higher the conductance or electric capacitance of skin surface. Via this method, the water content of the stratum corneum was quantitatively determined. The results are set forth below.

Improvement vs TOT4 hours+21%T8 hours+15%

[0059]The composition of example 1 when applied to skin using a roll-on dispenser had a significant moisturizing effect 4 hours after application as well as 8 hours after ap...

example 3

Application of the Composition of Example 1 to the Contour of the Eye—Effect on Bags and Dark Circles

[0060]The composition of example 1 was placed into a roll-on dispenser. 151 subjects applied the composition of example 1 to the contour of their eyes using the dispenser, twice a day, for four weeks. 50 of these subjects were subjected to clinical grading; 101 subjects were subject to self-assessment. All of the subjects had bags and / or dark circles in the contour of the eyes. All skin types were represented in the group of 151. The results are set forth below.

[0061]Clinical Grading—Efficacy on Dark Circles and Bags

[0062]Dermatologists evaluated the bags and dark circles of 50 subjects and determined:

Improvement after 4 weeksBags−11%Dark circles−12%

[0063]The composition of example 1 when applied to skin using a roll-on dispenser had a significant effect on both bags and dark circles after 4 weeks of use.

[0064]Self Assessment—Perceived Efficacy

[0065]101 subjects were provided questio...

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Abstract

The invention relates to compositions comprising at least one xanthine compound, preferably further comprising at least one agent which acts on capillary circulation and/or at least one natural moisturizing agent, which can be used to treat, or to reduce and/or minimize the appearance of, defects such as dark circles, bags and/or puffiness around eyes.

Description

FIELD OF THE INVENTION[0001]The present invention relates to compositions such as cosmetic or dermatologic compositions comprising at least one xanthine compound. Preferably, the compositions further comprise at least one agent which acts on capillary circulation and / or at least one natural moisturizing agent. Such compositions can be used, in particular, to treat or to reduce and / or minimize the appearance of defects such as dark circles, bags and / or puffiness around eyes.DISCUSSION OF THE BACKGROUND[0002]The eye contour (area around the eyes) has a very important aesthetic role since it immediately reflects fatigue, humor and age.[0003]The eye contour, owing to its structure and its high innervation, is an anatomical site that is particularly sensitive to environmental factors (UV rays, pollution, tobacco, etc.) and physiological factors (fatigue, stress, etc.).[0004]In humans, the eyes blink a thousand times per day, and the epidermis which surrounds them is very thin and not ver...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/49A61K8/02A61K8/73A61K8/44A45D40/26
CPCA61K8/42A61K8/494A61Q19/005A61K8/735A61K2800/874A61K8/63A61P17/00
Inventor POTIN, ANTHONYBOSSANT, ISABELLEAMAR, CAMILLE
Owner LOREAL SA
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