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2 results about "Cartilage Diseases" patented technology
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Cartilage disorders: Introduction. Diseases or conditions that affect the cartilage. Cartilage is a tough but elastic connective tissue that has no nerves or blood vessels in it. Cartilage to damage is difficult to heal. Some disorders that can affect the cartilage are chondrocalcinosis, chondrodysplasia and chondromalacia.
Process for preparing ectonucleotide pyrophosphatase / phosphodiesterase 1 (ENPP1) inhibitors
The present disclosure relates generally to processes for providing compounds that can be used as inhibitors of ectonucleotide pyrophosphatase / phosphodiesterase 1 (ENPP1), which inhibitors can be useful in treating or preventing soft bone diseases, such as hypophosphatasia (HPP).
Owner:1CBIO INC
Pharmaceutical composition for preventing or treating cartilage disease or inflammatory joint disease
PCT designated stageWO2026134900A1Skeletal disorderSkeletal/connective tissue cellsDisease3D cell culture
The present invention relates to a pharmaceutical composition for preventing or treating cartilage disease or inflammatory joint disease and a method for preparing a chondrospheroid having chondrocyte differentiation ability. The present invention provides a pharmaceutical composition comprising a stem cell-derived spheroid as an active ingredient for preventing or treating cartilage disease or inflammatory joint disease, and a method for preparing a chondrospheroid having chondrocyte differentiation ability, the method comprising the steps of: Inoculating stem cells into a three-dimensional (3D) cell culture vessel made of a plastic material; treating the stem cells inoculated into the 3D cell culture vessel with a chondrocyte differentiation-inducing factor; culturing the stem cells treated with the chondrocyte differentiation-inducing factor to form chondrospheroids; and separating the formed chondrospheroids.
Owner:DONGGUK UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION