The invention relates to a remote control device based on mobile phone wireless communication and a system and a lockset thereof; the device comprises a closed box body, a storage battery, a mobile phone terminal and a control circuit are arranged in the box body; the mobile phone terminal is arranged in the closed chamber of the box body, a purpose-made special SIM card is arranged on the mobile phone terminal, and a vibrator, a luminous device and a sound generator are connected on the mobile phone terminal, a vibration switch, a light-operated switch and a voice operated switch which are connected in series are arranged in the control circuit, the vibration switch, the light-operated switch and the voice operated switch are arranged in the closed chamber corresponding to the positions of the vibrator, the luminous device and the sound generator; a control element is connected on the control circuit, the control element is connected with home appliances or electronic locks by lead wires, so as to form a home appliance remote control system or a remote lockset; in the invention, light, sound and vibration are combined, so as to avoid interference and be beneficial to application and dissemination.