The invention provides lycium-ruthenicum, kiwi and grape composite fruit wine and a preparing method. The lycium-ruthenicum, kiwi and grape composite fruit wine has the composite function of kiwis andgrapes, fructus lycii is introduced for fermentation, and the prepared composite fruit wine is high in functionality and suitable for most crowds to drink. Compared with the prior art, the preparingmethod of the lycium-ruthenicum, kiwi and grape composite fruit wine is characterized by including the steps that kiwis are sliced up, the kiwis after slicing up, grape pulp liquid (grape pips and grape skins are smashed together) and lycium-ruthenicum grains are transferred to a fermentation barrel together in proportion, pectinase is added, and standing is carried out at the temperature of 18 DEG C to 27 DEG C; wine-making dry yeast is added, and temperature-control fermentation is carried out; fermentation is completed, clarification is carried out, and the composite fruit wine is obtained.According to the lycium-ruthenicum, kiwi and grape composite fruit wine and the preparing method, the lycium uthenicum, the kiwis and the grapes are compositely fermented, and the lycium-ruthenicum,kiwi and grape composite fruit wine is obtained; particularly, the grapes are subjected to complete wall-breaking treatment, and inhibiting sensitization factors in grape pips and resveratrol in the grape skins are released.