Medicine for treating rheumatic arthritis and its preparing method

A technology for rheumatoid and arthritis, applied in the field of preparation of the medicine, can solve the problems of large toxic and side effects, harmful to the human body, lack and the like

Inactive Publication Date: 2007-09-19
香港生物科技研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the existing problems are due to the characteristics of recurrent attacks of RA, long course of disease, and difficulty in curing. Western medicine often uses non-steroidal anti-inflammatory drugs (NSAIDS), immunosuppressants, and glucocorticoids for long-term treatment. Therefore, Western medicine often appears clinically. Serious adverse reactions, such as gastrointestinal bleeding, bone marrow suppression, renal impairment, pulmonary infection and other complications
Although the treatment of traditional Chinese medicine has the advantages of good curative effect and easy long-term use, it also has poor repeatability of the curative effect of traditional Chinese medicine, lack of standardization, and standardized research on pharmacology, medicinal chemistry, and pharmacodynamics.
There are also traditional Chinese medicine prescriptions and Chinese patent medicines for the treatment of RA. Some traditional Chinese medicines with high toxicity and side effects are often used, such as aconite, Zhichuanwu, Zhicaowu, Zhinxuezi, ephedra, Asarum, Fangji, Tripterygium wilfordii, Quanjie , centipede, ground beetle, poisonous snake, etc., are harmful to the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] The present invention selects following pharmaceutical composition by weight ratio:

[0071] Mulberry branch 2, Angelica 6,

[0072] Fangfeng 1, Sichuan Achyranthes bidentata 4;

[0073] The production method that above-mentioned each component is made into medicine of the present invention is:

[0074] 1. Take mulberry branch, angelica, windproof, and Achyranthes bidentata according to the above weight ratio, and select them separately to remove impurities, rinse them with clean water, chop them up, put them in an extraction tank, and add 8 times the weight of each drug respectively boiling water for 0.8 hours, each liquid medicine was filtered through a 200-mesh sieve, and the filtrate was taken. sieve filter;

[0075] 2. After filtering each medicinal material, extract the concentrated filtrate twice according to the above steps and conditions;

[0076] 3. Merge the concentrated solutions of the three extractions of the above-mentioned medicinal materials, spray ...

Embodiment 2

[0080] The present invention selects following pharmaceutical composition by weight ratio:

[0081] Mori 6, Angelica 2,

[0082] Fangfeng 4, Sichuan Achyranthes bidentata 1;

[0083] The production method that above-mentioned each component is made into medicine of the present invention is:

[0084] 1. According to the above weight ratio, take the medicinal materials of mulberry branch, angelica, windproof and Sichuan Achyranthes bidentata, respectively, after cleaning, removing impurities, rinsing with clean water, chopping, placing them in the extraction tank, adding 16 times the weight of each medicine respectively boiling water for 1.2 hours, each liquid medicine was filtered through a 200-mesh sieve, and the filtrate was taken. sieve filter;

[0085] 2. After filtering each medicinal material, extract the concentrated filtrate twice according to the above steps and conditions;

[0086] 3. Merge the concentrated solutions of the three extractions of the above-mentioned...

Embodiment 3

[0090] The present invention selects following pharmaceutical composition by weight ratio:

[0091] Mulberry branch 3, Angelica 4,

[0092] Fangfeng 2, Sichuan Achyranthes bidentata 3;

[0093] The production method that above-mentioned each component is made into medicine of the present invention is:

[0094] 1. According to the above weight ratio, take the medicinal materials of mulberry branch, angelica, windproof and Sichuan Achyranthes bidentata, respectively, after cleaning, removing impurities, rinsing with clean water, chopping, storing in the extraction tank, and adding 10 times the weight of each drug respectively boiling water for 1 hour, each liquid medicine was filtered through a 200-mesh sieve, and the filtrate was taken. sieve filter;

[0095] 2. After filtering each medicinal material, extract the concentrated filtrate twice according to the above steps and conditions;

[0096] 3. Merge the concentrated solutions of the three extractions of the above-mentio...

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PUM

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Abstract

The medicine for treating rheumatoid arthritis is prepared with mulberry twig, angelica, ledebouriella root and Sichuan achyranthes root in certain weight proportion, and through separate washing the materials, crushing, setting in extracting pot and adding water in 8-16 times, boiling for 0.8-1.2 hr, 200-mesh sieving to obtain filtrate, decompression concentrating to density of 1.05-1.08, 120-mesh sieving; repeating the above said process for twice; merging the filtrate of three times and spray drying to obtain the extracts of the materials; 60-mesh sieving, mixing the extracts and encapsulating to obtain medicine capsule. The medicine is suitable for preventing and treating rheumatoid arthritis.

Description

technical field [0001] The invention relates to a medicine for treating rheumatoid arthritis, specifically a Chinese patent medicine prepared from Chinese herbal medicines; the invention also relates to a preparation method of the medicine. Background technique [0002] The pathogenesis of Rheumatoid Arthritis (RA) is still not very clear in modern medicine, and it is generally believed to be an extremely complex autoimmune process. In traditional Chinese medicine, this disease belongs to the category of "Arthralgia Syndrome". Traditional Chinese medicine believes that cold, damp, fatigue, trauma, mental stimulation, and malnutrition can all be the cause of this disease. Insufficient nutrient and blood, weak qi and blood, loss of liver and kidney, and repeated exposure to wind, cold and damp are the main factors of this disease. [0003] The incidence of RA is still on the rise. RA disease has the characteristics of recurrent attacks and progressive lesions, and has a hig...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/605A61K36/238A61K36/232A61K36/21A61K9/48A61P29/00A61P19/02
Inventor 何国强程新敏杨成安魏英伟陈志刚黄锦华游佩珊刘子芸林壮大
Owner 香港生物科技研究院有限公司
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