Water dispersible tablet of flumorph

A flumorpholine and dispersible tablet technology, applied in the field of pesticide processing, can solve problems such as poor control of dosage, inconvenience to the environment, pollution, etc., and achieve the effects of being beneficial to storage, less environmental pollution, and beneficial to container configuration

Active Publication Date: 2008-04-23
SHENYANG SINOCHEM AGROCHEMICALS R&D CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to overcome the disadvantages that the existing dosage forms are not easy to control, inconvenient to store and transport, and easily cause environmental pollution, the present invention proposes a new dosage form of flumorph tablets

Method used

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  • Water dispersible tablet of flumorph

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1 35% flumorph water dispersible tablet

[0015] Flumorph 35g

[0016] Microcrystalline Cellulose 14g

[0017] Polyvinylpyrrolidone 4 g

[0018] Sodium carbonate 6 grams

[0019] citric acid 6 grams

[0020] NNO 5g

[0021] Sodium Lignosulfonate 5g

[0022] Sodium dodecylbenzene sulfonate 1 g

[0023] Magnesium stearate 2 g

[0024] Talc powder 2 grams

[0025] Calcium carbonate light up to 100g

Embodiment 2

[0026] Embodiment 2 30% flumorph water dispersible tablet

[0027] Flumorph 30g

[0028] Microcrystalline Cellulose 11g

[0029] Polyvinylpyrrolidone 2 grams

[0030] Sodium carbonate 6 grams

[0031] citric acid 6 grams

[0032] NNO 5g

[0033] Sodium dodecylbenzene sulfonate 1 g

[0034] Magnesium stearate 1 g

[0035] Silicone 2 grams

[0036] Calcium carbonate light up to 100g

Embodiment 3

[0037] Embodiment 3 20% flumorph water dispersible tablet

[0038] Flumorph 20g

[0039] 16 g microcrystalline cellulose

[0040] Polyvinylpyrrolidone 4 g

[0041] Sodium carbonate 6 grams

[0042] citric acid 6 grams

[0043] NNO 5g

[0044] Sodium dodecylbenzene sulfonate 1 g

[0045] Magnesium stearate 1 g

[0046] Silicone 2 grams

[0047] Talc powder 1 g

[0048] Calcium carbonate light up to 100g

[0049] Water Dispersibility Test

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Abstract

The invention discloses a flumorph water dispersing tablet, which is prepared from flumorph reagents, crumbling agent, binding agent, effervescent agent, wetting agent, emulsifying agent, and bulking agent through mixing, disintegrating, and tabletting with total powder direct pelleting method. Compared with the traditional dosage types, the water dispersing tablet has the advantages of high effectiveness, ease and convenience in use, transportation and storage, less environmental pollution.

Description

technical field [0001] The invention belongs to the field of pesticide processing and relates to a new dosage form of the agricultural fungicide flumorph and its processing and application. Background technique [0002] Flumorph (chemical name: 4-[3-(4-fluorobase)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine) is widely used as an agricultural fungicide Prevention and control of various crop diseases, especially for downy mildew and Phytophthora. Chinese patent CN1167568A discloses the bactericidal activity and preparation method of the compound and its preparation. Along with the further expansion of popularization and application of flumorph, it is found that there are many deficiencies in the dosage forms currently used. For example, it is difficult to control the dosage of wettable powder, especially in small doses; the emulsifiable concentrate contains a large amount of organic solvents such as xylene, which seriously pollutes the environment; at the same time, the stora...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N43/84
Inventor 孔宪斌王勇张宗俭司乃国徐妍张文革
Owner SHENYANG SINOCHEM AGROCHEMICALS R&D CO LTD
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